LEADER 00990cam0-22003611i-450- 001 990001139930403321 005 20130614092301.0 035 $a000113993 035 $aFED01000113993 035 $a(Aleph)000113993FED01 035 $a000113993 100 $a20001205d1981----km-y0itay50------ba 101 0 $aita 102 $aIT 200 1 $a<>calcolo sublime$estoria dell'analisi matematica da Euler a Weierstrass$fUmberto Bottazzini 210 $aTorino$cBoringhieri$d1981 225 1 $aLezioni e seminari 610 0 $aAnalisi matematica$aStoria 676 $a515$v20$zita 700 1$aBottazzini,$bUmberto$026182 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a990001139930403321 952 $a10-L-7$b21377$fMA1 952 $aCPDM-01-001$b102 CPDM$fMA1 952 $a02 50 F 5$b3701$fFINBN 959 $aMA1 959 $aFINBN 962 $a01A05 962 $a26-03 962 $a30-03 996 $aCalcolo sublime$9344245 997 $aUNINA LEADER 02797nam 22005894a 450 001 9911020228903321 005 20200520144314.0 010 $a9786610275663 010 $a9781280275661 010 $a1280275669 010 $a9780470012994 010 $a0470012994 010 $a9780470012987 010 $a0470012986 035 $a(CKB)1000000000239297 035 $a(EBL)232675 035 $a(OCoLC)224426090 035 $a(SSID)ssj0000137284 035 $a(PQKBManifestationID)11954164 035 $a(PQKBTitleCode)TC0000137284 035 $a(PQKBWorkID)10088011 035 $a(PQKB)11232486 035 $a(MiAaPQ)EBC232675 035 $a(Perlego)2777827 035 $a(EXLCZ)991000000000239297 100 $a20041130d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aDesign of studies for medical research /$fDavid Machlin, Michael J. Campbell 210 $aHoboken, NJ $cWiley$dc2005 215 $a1 online resource (286 p.) 300 $aDescription based upon print version of record. 311 08$a9780470844953 311 08$a0470844957 320 $aIncludes bibliographical references (p. [246]-254) and index. 327 $aDesign of Studies for Medical Research; Contents; Preface; Chapter 1 What is Evidence?; Chapter 2 Measurement, Forms and Questionnaires; Chapter 3 Principles of Study Size Calculation; Chapter 4 Randomisation; Chapter 5 Cross-sectional and Longitudinal Studies; Chapter 6 Surveys, Cohort and Case-Control Studies; Chapter 7 Clinical Trials - General Issues; Chapter 8 Early Clinical Trials; Chapter 9 Phase III Trials; Chapter 10 Diagnosis; Chapter 11 Prognostic Factor Studies; References; Tables; Index 330 $aThe same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development. With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design. This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples f 606 $aMedicine$xResearch$xMethodology 615 0$aMedicine$xResearch$xMethodology. 676 $a610/.72 700 $aMachin$b David$f1939-$0520765 701 $aCampbell$b Michael J$0125733 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911020228903321 996 $aDesign of studies for medical research$94418019 997 $aUNINA