LEADER 01084nam0-22003731i-450- 001 990000700920403321 005 20160330095210.0 035 $a000070092 035 $aFED01000070092 035 $a(Aleph)000070092FED01 035 $a000070092 100 $a20020821d1982----km-y0itay50------ba 101 0 $aita 102 $aIT 105 $aa-------001yy 200 1 $a<>Mackley Houses di Kastner e Stonorov a Philadelphia$f1931-1935 210 $aRoma$cOfficina$d1982 215 $a171 p.$cill.$a21 cm 225 1 $aArchitettura$eOpere$v6 610 0 $aKastner, Alfred e Oscar Stonorov$aFiladelfia$aMackley Houses 610 0 $aEdilizia popolare 676 $a728.92 700 1$aSantostefano,$bPiero$035680 702 1$aKastner,$bAlfred 702 1$aStonarov,$bOscar 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000700920403321 952 $aMON B 417$b14384$fFARBC 952 $a10.558$b5128$fDARST 959 $aFARBC 959 $aDARST 996 $aMackley Houses di Kastner e Stonorov a Philadelphia$9323712 997 $aUNINA LEADER 04945nam 22004575 450 001 9910878974203321 005 20250807135521.0 010 $a3-031-62648-6 024 7 $a10.1007/978-3-031-62648-7 035 $a(MiAaPQ)EBC31582825 035 $a(Au-PeEL)EBL31582825 035 $a(CKB)33729297800041 035 $a(DE-He213)978-3-031-62648-7 035 $a(EXLCZ)9933729297800041 100 $a20240805d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCurrent and Future Advances in Male Infertility $eA Compendium for Clinicians and Researchers /$fedited by Ashok Agarwal, Ramadan Saleh, Florence Boitrelle, Rupin Shah 205 $a1st ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2024. 215 $a1 online resource (405 pages) 311 08$a3-031-62647-8 320 $aIncludes bibliographical references and index. 327 $aSection I: Declining Male reproductive Health -- Clinical implications of WHO 6th edition on semen analysis -- Endocrine disrupting chemicals (EDCs) and male Infertility -- Lifestyle modifications and male Infertility -- Impact of testicular/non-testicular cancer on male fertility -- Section II: Sperm Chromatin Integrity and Fertility -- Impact of sperm DNA fragmentation (SDF) on natural and assisted conception -- Section III: Male Oxidative Stress Infertility (MOSI) -- Pathophysiology of seminal oxidative stress -- Management of male oxidative stress infertility (MOSI) -- Section IV: Genetics and Epigenomic of Male Infertility -- Advances in genetics of male infertility -- Epigenetic alterations in male infertility -- Section V: Varicocele Revisited -- New insights into the patho-physiology of varicocele in male infertility -- Clinical dilemmas and controversies in varicocele management -- Section VI: Management of Male Accessory Gland Infection (MAGI) -- Challenges in the diagnosis and treatment of MAGI -- Section VII: Sexual Dysfunction in Male Infertility -- Epidemiologic features and management of sexual dysfunctions in infertile men -- Section VIII: Current Challenges and Future Perspectives of Male Infertility -- Hypogonadism in infertile men: a clinical minefield -- Challenges in the management of non-obstructive azoospermia (NOA) -- Alternative approaches to treatment of male infertility -- A comprehensive guide to sperm optimization prior to ART -- Role of artificial intelligence in the management of male infertility -- New frontiers of research and therapy in male infertility. 330 $aInfertility is an important health problem affecting around 15% of couples worldwide, with profound psycho-social consequences and impairment of patients? quality of life. It has been shown that the male factor is solely and partially implicated in 20-50% of the cases of infertility. Male infertility is a complex issue that can be related to a variety of congenital or acquired factors that lead to a decline in the quantity and/or the quality of semen. Over the recent years, there have been major advances in basic understanding of the factors that regulate male fertility, the diagnostic tests for assessment of male fertility potential, and the therapeutic options for the management of male subfertility/infertility. However, despite advances in technologies and diagnostic methods in the field of andrology, there remains a significant subset of these subfertile men who are classified as having unexplained or idiopathic male infertility. In addition, there are ongoing debates and controversies on the clinical management of infertile men under certain conditions like varicocele, genital tract inflammation/infection or non-obstructive azoospermia. This book discusses advances in cellular, molecular, and genetic aspects of spermatogenesis and sperm evaluation in the context of clinical scenarios. It also addresses clinical dilemmas and controversies through a discussion of the basic science underlying these conditions. The authors form an impressive international collaboration to provide a unique perspective that specializes in all key areas of andrology. Current and Future Advances in Male Infertility provides insights into strategies to reduce the burden of male gonadotoxins, to enhance men?s fecundity and to help optimize the care of infertile men. It aims to bridge the gap between researchers and clinicians by integrating basic science and clinical application. 606 $aReproductive health 606 $aReproductive Medicine 615 0$aReproductive health. 615 14$aReproductive Medicine. 676 $a616.692 702 $aAgarwal$b Ashok 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910878974203321 996 $aCurrent and Future Advances in Male Infertility$94262121 997 $aUNINA