LEADER 00760nam0-22002771i-450- 001 990000509290403321 005 20090323105348.0 035 $a000050929 035 $aFED01000050929 035 $a(Aleph)000050929FED01 035 $a000050929 100 $a20020821d1977----km-y0itay50------ba 101 0 $aita 105 $aa-------001yy 200 1 $aFortran base$edispensa didattica$fSperry-UNIVAC 210 $a[S.l.]$cSperry Rand Italia$d1977 215 $a1 v. (paginaz. varia)$cill.$d28 cm 610 0 $aLinguaggi di programmazione 610 0 $aFortran 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000509290403321 952 $a10 P.T. 502$b10201$fDINEL 959 $aDINEL 996 $aFortran base$9327158 997 $aUNINA LEADER 03131oam 22005413 450 001 9910964928103321 005 20251017110112.0 010 $a0-309-45029-2 010 $a0-309-45027-6 035 $a(CKB)3710000001064498 035 $a(MiAaPQ)EBC4806755 035 $a(DNLM)1701576 035 $a(EXLCZ)993710000001064498 100 $a20240208d2017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDeveloping Multimodal Therapies for Brain Disorders $eProceedings of a Workshop 205 $a1st ed. 210 1$aWashington, D.C. :$cNational Academies Press,$d2017. 210 4$dİ2017. 215 $a1 online resource (97 pages) 311 08$a0-309-45026-8 327 $aIntroduction -- Multimodal therapy: overview of principles, barriers, and opportunities -- Exploring the state of the science -- Exploring the state of the science -- Regulatory and reimbursement considerations -- Trial designs to establish efficacy and safety in multimodal therapies -- Developing multimodal therapies: practical considerations relating to industry -- Role of research funders in multimodal therapy development -- Appendix A: References -- Appendix B: Workshop agenda -- Appendix C: Registered participants. 330 $a"Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potential--and perhaps essential--ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. 606 $aBrain$xDiseases$xAdjuvant treatment$vCongresses 606 $aCombined modality therapy$vCongresses 606 $aCombined Modality Therapy 606 $aBrain Diseases$xtherapy 615 0$aBrain$xDiseases$xAdjuvant treatment 615 0$aCombined modality therapy 615 12$aCombined Modality Therapy. 615 12$aBrain Diseases$xtherapy. 676 $a616.8/046 700 $aStroud$b Clare$01601279 701 $aKeren$b Noam I$01852304 701 $aBain$b Lisa$01852305 712 02$aNational Academies of Sciences, Engineering, and Medicine (U.S.).$bForum on Neuroscience and Nervous System Disorders, 712 12$aMultimodal Therapies for Brain Disorders (Workshop)$f(2016 :$eWashington, D.C.),$bauthor. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910964928103321 996 $aDeveloping Multimodal Therapies for Brain Disorders$94447274 997 $aUNINA LEADER 03558nam 22005895 450 001 9910300184003321 005 20200702081228.0 010 $a3-662-45444-0 024 7 $a10.1007/978-3-662-45444-2 035 $a(CKB)3710000000342582 035 $a(EBL)1966131 035 $a(SSID)ssj0001424473 035 $a(PQKBManifestationID)11801993 035 $a(PQKBTitleCode)TC0001424473 035 $a(PQKBWorkID)11383625 035 $a(PQKB)10981128 035 $a(DE-He213)978-3-662-45444-2 035 $a(MiAaPQ)EBC1966131 035 $a(PPN)183517490 035 $a(EXLCZ)993710000000342582 100 $a20150121d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFace Transplantation $ePrinciples, Techniques and Artistry /$fby Juan P. Barret, Veronica Tomasello 205 $a1st ed. 2015. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2015. 215 $a1 online resource (156 p.) 300 $aDescription based upon print version of record. 311 $a3-662-45443-2 320 $aIncludes bibliographical references. 327 $aIntroduction and Background -- History of the Face Transplantation -- Composite Tissue Allotransplantation (CTA) -- Indications of Facial Transplantation -- Evaluation of the Candidate for Facial Transplantation -- Evaluation of Donors -- Legal, Ethical and Psychological Issues in Facial Transplantation -- Face as an Organ: Functional Anatomy -- Types of Face Transplants -- Requirements for a Multidisciplinary Team -- Surgical Technique of Facial Transplantation -- Immunological Issues and Immunomodulation -- An Overview of the World`s Global Experience. 330 $aThis book brings together all the relevant available science behind face transplants. It is comprehensive in its coverage, encompassing patient and donor evaluation, ethics, legal issues, psychological issues, types of transplant, surgical technique, issues relating to immunosuppression, follow-up protocols, and current outcomes. Facial transplantation, which allows the replacement of missing anatomy with a perfect match based on transplant medicine principles, has become the most striking innovation in plastic surgery of the twenty-first century as surgeons and scientists progress from reconstructive surgery to restorative surgery. A robust team approach is, however, necessary to produce safe and efficient outcomes, and numerous questions are arising, from technical issues to ethical dilemmas. The reader will discover in this volume all the information required in order to understand this new discipline and to be able to set up a program of facial transplantation. 606 $aSurgery, Plastic 606 $aTransplantation of organs, tissues, etc 606 $aPlastic Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59087 606 $aTransplant Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59117 615 0$aSurgery, Plastic. 615 0$aTransplantation of organs, tissues, etc. 615 14$aPlastic Surgery. 615 24$aTransplant Surgery. 676 $a610 676 $a617952 676 $a617954 700 $aBarret$b Juan P$4aut$4http://id.loc.gov/vocabulary/relators/aut$01061666 702 $aTomasello$b Veronica$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910300184003321 996 $aFace Transplantation$92519591 997 $aUNINA