LEADER 00818nam2-22003131i-450- 001 990000867100403321 005 20001010 010 $a9971-950-14-6 035 $a000086710 035 $aFED01000086710 035 $a(Aleph)000086710FED01 035 $a000086710 100 $a20001010d--------km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $a1 : XV, 464 p. 210 $aSingapore$cWorld Scientific$d1982 215 $a2 v. (p. 1076 compless.) 22 cm 461 0$1001000082591$12001$aUnity of forces in the universe 676 $a530 700 1$aZee,$bA.$040332 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000867100403321 952 $a000086710000001$fFINBN 959 $aFINBN 996 $a1 : XV, 464 p$9349307 997 $aUNINA DB $aING01 LEADER 01065nam0 22002893i 450 001 SUN0090360 005 20120709101131.144 010 $a88-15-07398-1 100 $a20120709d2000 |0itac50 ba 101 $aita 102 $aIT 105 $a|||| ||||| 200 1 $aGiustizia amministrativa$fMario Nigro 205 $a5. ed.$fa cura di Enzo Cardi e Alessandro Nigro 210 $aBologna$c Il mulino$d2000 215 $a410 p.$d24 cm. 620 $dBologna$3SUNL000003 676 $a342$cDiritto costituzionale, diritto amministrativo, diritto pubblico in generale$v21 700 1$aNigro$b, Mario$3SUNV000913$0342773 702 1$aNigro$b, Alessandro$f1942-$3SUNV000914 702 1$aCardi$b, Enzo$3SUNV000915 712 $aIl mulino$3SUNV000011$4650 801 $aIT$bSOL$c20210419$gRICA 912 $aSUN0090360 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA$d00CONS IV.Ce.42 $e00BFG5690 20120711 996 $aGiustizia amministrativa$9196300 997 $aUNICAMPANIA LEADER 02665nam 2200529z- 450 001 9910637793003321 005 20231214133632.0 010 $a3-0365-5224-3 035 $a(CKB)5470000001631606 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/94543 035 $a(EXLCZ)995470000001631606 100 $a20202212d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenetics of Hearing Impairment 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (314 p.) 311 $a3-0365-5223-5 330 $aThe inner ear is a complex machinery at the cellular and molecular levels. Many different genes and proteins play roles in the development and maintenance of its structure and function, through participating in diverse molecular networks. A defect in any of these components can result in the loss of hearing. Consequently, hearing impairment encompasses a wide variety of disorders that are clinically and genetically heterogeneous. Understanding their genetic causes and their pathophysiological mechanisms, and characterizing the resulting phenotypes, are essential for developing novel therapies that target the specific defects. The articles and reviews in this book are representative of the many research lines that are currently active in the field, including recent advances in the genes and mutations involved in hearing impairment, the mechanisms through which mutations result in different syndromic or non-syndromic disorders, and the description of the associated phenotypes in humans and in animal models. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 606 $aGenetics (non-medical)$2bicssc 610 $ainner ear 610 $ahearing impairment 610 $agene identification 610 $adisease-causing mutations 610 $agenetic epidemiology 610 $agenotype&ndash 610 $aphenotype correlations 610 $apathophysiological mechanisms 610 $aomics 610 $agenome editing 610 $agene therapy 615 7$aResearch & information: general 615 7$aBiology, life sciences 615 7$aGenetics (non-medical) 700 $adel Castillo$b Ignacio$4edt$01331652 702 $aKremer$b Hannie$4edt 702 $adel Castillo$b Ignacio$4oth 702 $aKremer$b Hannie$4oth 906 $aBOOK 912 $a9910637793003321 996 $aGenetics of Hearing Impairment$93040534 997 $aUNINA