01226cam2 22003011 450 SOBE0007980120240409130245.0376530412320240409d1988 |||||ita|0103 bagerDE<<2: Die >>Welt als Wille und Vorstellung. 1Arthur Schopenhauer4. Auflagedurchgesehen von Angelika HübscherMannheimBrockhaus1988XXXII, 655 p.22 cm001SOBE000797772001 Sämtliche Werke / Arthur Schopenhauer ; nach der ersten von Julius Frauenstädt besorgten Gesamtausgabe neu bearbeitet und herausgegeben von Arthur Hübscher2<<Die >>Welt als Wille und VorstellungSOBA0003078714796Schopenhauer, ArthurAF00010907070134228Hübscher, AngelikaA600200058154070ITUNISOB20240409RICAUNISOBUNISOB100181347SOBE00079801M 102 Monografia moderna SBNM100011600-2SI18134720240405acquistoNmenleUNISOBUNISOB20240409093958.020240409094042.0menleWelt als Wille und Vorstellung14796UNISOB02919nam 2200469z- 450 991022003580332120210211(CKB)3800000000216419(oapen)https://directory.doabooks.org/handle/20.500.12854/49956(oapen)doab49956(EXLCZ)99380000000021641920202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierImaging Synapse Structure and FunctionFrontiers Media SA20171 online resource (125 p.)Frontiers Research Topics2-88945-175-5 Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.Neurosciencesbicsscbrain circuitscalcium imagingconnectomicsElectron microscopyfunctional imagingmetabotropic glutamate receptorsoptogeneticsSchizophreniasuper-resolutionSynaptic Transmissionsynaptic vesicle traffickingNeurosciencesGeorge J. Augustineauth1331622Marc FivazauthBOOK9910220035803321Imaging Synapse Structure and Function3040507UNINA