01280nam0 22003253i 450 RMB081574720251003044335.0978889385241820231002d2022 ||||0itac50 baitaitaitz01i xxxe z01nz01ncRDAcarrierMatematica finanziariaDaniele RitelliBolognaSocietà Editrice Esculapio2022VIII, 187 p.24 cmAccesso TextinCloudMatematica finanziariaRMB0815749CFIV1376793562416Matematica finanziariaFIRCFIC006216E332.0151ECONOMIA FINANZIARIA. PRINCIPÎ SCIENTIFICI. MATEMATICA23Ritelli, DanieleCFIV137679070614365ITIT-00000020231002IT-BN0095 NAP 01BCA Comprende monografie e periodici di diritto, testi di ingegneria, di scienze e tecnologia di nuova acquisizione. RMB0815747Biblioteca Centralizzata di Ateneo1 v. 01BCA SC. TECNOL 329 01 0000128205 VMA A4 1 v.Y 2023092220231002 01Matematica finanziaria3562416UNISANNIO04681nam 2200673 a 450 991095676690332120251017110056.09786612554353978030915235803091523569781282554351128255435297803091509580309150957(CKB)2560000000014510(EBL)3378601(SSID)ssj0000427213(PQKBManifestationID)11315811(PQKBTitleCode)TC0000427213(PQKBWorkID)10391169(PQKB)10500302(MiAaPQ)EBC3378601(Au-PeEL)EBL3378601(CaPaEBR)ebr10379894(CaONFJC)MIL255435(OCoLC)923281617(Perlego)4739920(DNLM)1540445(EXLCZ)99256000000001451020100514d2010 uy 0engurcn|||||||||txtccrReview of the Environmental Protection Agency's draft IRIS assessment of tetrachloroethylene /Committee to Review EPA's Toxicological Assessment of Tetrachloroethylene, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies1st ed.Washington, D.C. National Academies Press20101 online resource (185 p.)Description based upon print version of record.9780309150941 0309150949 Includes bibliographical references.""Front Matter""; ""Preface""; ""Abbreviations""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Overview of the Toxicokinetics of Tetrachloroethylene""; ""3 Neurotoxicity""; ""4 Reproductive and Developmental Effects""; ""5 Genotoxicity""; ""6 Hepatic Toxicity and Cancer""; ""7 Renal Toxicity and Cancer""; ""8 Hematopoietic Effects""; ""9 General Review of Epidemiologic Evidence Pertaining to Cancer""; ""10 Reference Values for Tetrachloroethylene""; ""11 Cancer Risk Estimates for Tetrachloroethylene""; ""12 Moving Beyond the Current State of Practice""; ""References""""Appendix A: Biographic Information on the Committee on Tetrachloroethylene""""Appendix B: Dissenting Statement and Rebuttal"""Tetrachloroethylene is a volatile, chlorinated organic hydrocarbon that is widely used as a solvent in the dry-cleaning and textile-processing industries and as an agent for degreasing metal parts. It is an environmental contaminant that has been detected in the air, groundwater, surface waters, and soil. In June 2008, the U.S. Environmental Protection Agency released its draft Toxicological Review of Tetrachloroethylene (Perchloroethylene) (CAS No. 127-18-4) in Support of Summary Information on the Integrated Risk Information System (IRIS). The draft IRIS assessment provides quantitative estimates of cancer and noncancer effects of exposure to tetrachloreothylene, which will be used to establish airquality and water-quality standards to protect public health and to set cleanup standards for hazardous waste sites. At the request of EPA, the National Research Council conducted an independent scientific review of the draft IRIS assessment of tetrachloroethylene from toxicologic, epidemiologic, and human clinical perspectives. The resulting book evaluates the adequacy of the EPA assessment, the data and methods used for deriving the noncancer values for inhalation and oral exposures and the oral and inhalation cancer unit risks posed by tetrachloroethylene; evaluates whether the key studies underlying the draft IRIS assessment are of requisite quality, reliability, and relevance to support the derivation of the reference values and cancer risks; evaluates whether the uncertainties in EPA's risk assessment were adequately described and, where possible, quantified; and identifies research that could reduce the uncertainty in the current understanding of human health effects associated with tetrachloroethylene exposure"--Publisher's description.TetrachloroethyleneToxicologyTetrachloroethyleneRisk assessmentTetrachloroethyleneToxicology.TetrachloroethyleneRisk assessment.615.9512National Academies Press (U.S.)MiAaPQMiAaPQMiAaPQBOOK9910956766903321Review of the Environmental Protection Agency's draft IRIS assessment of tetrachloroethylene4363785UNINA