02066cam a22003858a 4500991003522989707536080401s2008 nju b 001 0 eng d9789812707048 (hardcover)9812707042 (hardcover)b13709513-39ule_instDip.to Fisicaeng572.8028522LC QH324.2510.62Zhou, Xiaobo628188Computational systems bioinformatics :methods and biomedical applications /by Xiaobo Zhou and Stephen T.C. Wong[Hackensack, N.J.] :World Scientific Pub.,2008x, 387 p. :ill. (some col.), diagrs., graphs, tables ;23 cmIncludes bibliographical references and indexMathematical, statistical, and data mining principles -- Missing value estimation using KNN and Bayesian methods -- Normalization, scaling, and discretization -- Cross-platform comparison -- Discovering differential biomarkers -- Gene selection and classification -- Gene clustering -- Gene predictionReverse engineering : gene regulatory network construction and its behavior -- Motif detection and transcription factor binding site (TFBS) identification -- Gene interaction based on combined microarray and sequence technology -- Protein structure informatics -- Biomarker discovery from proteomics -- Bio-imaging informaticsComputational biologyDNA microarraysBioinformaticsComputational BiologyMethodsMicroarray AnalysisMethods.Oligonucleotide Array Sequence AnalysisMethodsStatisticsMethodsWong, Stephen T.C..b1370951328-01-1401-04-08991003522989707536LE006 510.62+510.65 ZHO12006000161756le006pE44.53-l- 03030.i1470650701-04-08Computational systems bioinformatics1229262UNISALENTOle00601-04-08ma -engnju00