02923nam 2200685 450 991045503250332120210507223140.00-231-50157-910.7312/maru12658(CKB)111056485391322(EBL)909148(OCoLC)818856834(SSID)ssj0000165129(PQKBManifestationID)11924510(PQKBTitleCode)TC0000165129(PQKBWorkID)10141353(PQKB)11184387(MiAaPQ)EBC909148(DE-B1597)459103(OCoLC)51574588(OCoLC)979682858(DE-B1597)9780231501576(Au-PeEL)EBL909148(CaPaEBR)ebr10956755(CaONFJC)MIL690474(EXLCZ)9911105648539132220020123h20021966 uy| 1engur|n|---|||||txtccrGrass for my pillow /Saiichi Maruya ; translated by Dennis KeeneNew York, New York :Columbia University Press,[2002]©19661 online resource (521 p.)A Pacific Basin Institute bookColumbia Asian studies seriesDescription based upon print version of record.1-322-59192-X 0-231-12658-1 Frontmatter --CONTENTS --Translator's Introduction --One --Two --Three --Four --Five --Six --Seven --Postscript: Sugiura's TravelsFirst published in Japanese in 1966, the debut novel of the critically acclaimed author of Singular Rebellion is an unusual portrait of a deeply taboo subject in twentieth-century Japanese society: resistance to the draft in World War II. In 1940 Shokichi Hamada is a conscientious objector who dodges military service by simply disappearing from society, taking to the country as an itinerant peddler by the name of Sugiura until the end of the war in 1945. In 1965, Hamada works as a clerk at a conservative university, his war resistance a dark secret of the past that present-day events force into the light, confronting him with unexpected consequences of his refusal to conform twenty years earlier.Pacific Basin Institute book.Columbia Asian studies series.Conscientious objectorsJapanFictionWorld War, 1939-1945Conscientious objectorsJapanFictionElectronic books.Conscientious objectorsWorld War, 1939-1945Conscientious objectors895.6/35Maruya Saiichi1925-2012,756411Keene Dennis1934-2007,MiAaPQMiAaPQMiAaPQBOOK9910455032503321Grass for my pillow2471850UNINA00979oam 2200265z- 450 991015482680332120180629082658.01-68103-324-0(CKB)3710000000972231(EXLCZ)99371000000097223120190224c2017uuuu -u- -engEaster /by Rachel GrackBellwether Media1-62617-594-2 We see Easter! -- What is Easter? -- Who celebrates Easter? -- How did Easter start? -- When is Easter celebrated today? -- Easter traditions around the world!"Relevant images match informative text in this introduction to Easter. Intended for students in kindergarten through third grade"--Provided by publisher.EasterJuvenile literatureEaster263/.93Koestler-Grack Rachel A.1973-1246456BOOK9910154826803321Easter2893906UNINA01076nam a2200241 i 4500991001090709707536050610s2005 it 000 0 ita d8832453878b13318962-39ule_instSet. Economiaita344.4506Mangani, Roberto293328Guida pratica agli appalti pubblici di lavori :dalla legge Merloni alla legge obiettivo : istituti, principi e norme tra Stato e regioni : aggiornato con la legge 18 aprile 2005, n. 62 (Legge comunitaria 2004) /Roberto ManganiMilano :Il Sole 24 ore,2005xiii, 280 p. ; 22 cmEdilizia e territorioLavori pubbliciAppaltiLegislazione comunitaria.b1331896221-11-1410-06-05991001090709707536LE025 ECO 344 MAN01.0112025000135390le025pE29.00-l- 0115110.i1409160415-06-05Guida pratica agli appalti pubblici di lavori1106084UNISALENTOle02510-06-05ma -itait 0001013nam0 22002651i 450 UON0012496720231205102732.55820020107d1961 |0itac50 baengCN|||| 1||||Japanese studies on Japan & the Far EastDeng SiyuHong KongHong Kong University Press1961X, 485 p.24 cmCNHong KongUONL000075GIA GEN B IGIAPPONE - BIBLIOGRAFIEATENGSsu-YuUONV010372412044Hong Kong University PressUONV249277650DENG SiyuTENG, Ssu-YuUONV039483ITSOL20240220RICASIBA - SISTEMA BIBLIOTECARIO DI ATENEOUONSIUON00124967SIBA - SISTEMA BIBLIOTECARIO DI ATENEOSI GIA GEN B I 019 SI YAM110 5 019 Japanese studies on Japan & the Far East1317707UNIOR04472nam 2200889z- 450 991055748740332120220111(CKB)5400000000042958(oapen)https://directory.doabooks.org/handle/20.500.12854/77002(oapen)doab77002(EXLCZ)99540000000004295820202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNanoscale Self-Assembly: Nanopatterning and MetrologyBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (124 p.)3-0365-1961-0 3-0365-1960-2 The self-assembly process underlies a plethora of natural phenomena from the macro to the nano scale. Often, technological development has found great inspiration in the natural world, as evidenced by numerous fabrication techniques based on self-assembly (SA). One striking example is given by epitaxial growths, in which atoms represent the building blocks. In lithography, the use of self-assembling materials is considered an extremely promising patterning option to overcome the size scale limitations imposed by the conventional photolithographic methods. To this purpose, in the last two decades several supramolecular self-assembling materials have been investigated and successfully applied to create patterns at a nanometric scale. Although considerable progress has been made so far in the control of self-assembly processes applied to nanolithography, a number of unresolved problems related to the reproducibility and metrology of the self-assembled features are still open. Addressing these issues is mandatory in order to allow the widespread diffusion of SA materials for applications such as microelectronics, photonics, or biology. In this context, the aim of the present Special Issue is to gather original research papers and comprehensive reviews covering various aspects of the self-assembly processes applied to nanopatterning. Topics include the development of novel SA methods, the realization of nanometric structures and devices, and the improvement of their long-range order. Moreover, metrology issues related to the nanoscale characterization of self-assembled structures are addressed.Nanoscale Self-AssemblyTechnology: general issuesbicssc(S)TEM3D printinganalytical centrifugationanalytical ultracentrifugationarbitrary distributionblock copolymerblock copolymer self-assemblyblock copolymersblock copolymers (BCPs)chemo-epitaxyclassification of nanoparticlescolloidal clusterscolloidal moleculescolloidal nanospheresconjugated polymersdensity gradient centrifugationdeposition surfacedifferential centrifugal sedimentationdirect laser-writingdirected self-assemblydirected self-assembly (DSA)disk centrifugelarge scaleline edge roughness (LER)line edge roughness LERline width roughness (LWR)line/space patterningmultimaterialsnano-resolutionnanoparticlesnanospheres lithographynanostructure metrologyphotoluminescence quenchingpolyfullerenespolymer interfacepolystyrene-block-polymethylmethacrylate (PS-b-PMMA)processing by convective self-assemblyrapiditysedimentationself-assemblyseparationsequential infiltration synthesisSTEM-EELS of PS and PMMAtannic acidthin films and microstructureTechnology: general issuesFerrarese Lupi Federicoedt1289232Ferrarese Lupi FedericoothBOOK9910557487403321Nanoscale Self-Assembly: Nanopatterning and Metrology3021118UNINA04955nam 2200469z- 450 991034673720332120210212(CKB)4920000000094342(oapen)https://directory.doabooks.org/handle/20.500.12854/60472(oapen)doab60472(EXLCZ)99492000000009434220202102d2018 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierTailoring NK Cell Receptor-Ligand Interactions: an Art in Evolution. 2nd EditionFrontiers Media SA20181 online resource (407 p.)Frontiers Research Topics2-88945-663-3 Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is mediated by positive signals transduced by activating receptors upon engagement of ligands on target surface. These stimulatory pathways are counterbalanced by inhibitory receptors that raise NK cell activation threshold through negative antagonist signals. While regulatory effects are necessary for physiologic control of autoimmune aggression, they may restrain the ability of NK cells to activate against disease. Overcoming this barrier to immune surveillance, multiple approaches to enhance NK-mediated responses are being investigated since two decades. Propelled by considerable advances in the understanding of NK cell biology, these studies are critical for effective translation of NK-based immunotherapy principles into the clinic. In humans, dominant inhibitory signals are transduced by Killer Immunoglobulin Like Receptors (KIR) recognizing cognate HLA class I on target cells. Conversely, KIR recognition of "missing self-HLA" - due to HLA loss or HLA/ KIR mismatch - triggers NK-mediated tumor rejection. Initially observed in murine transplant models, these antitumor effects were later found to have important implications for the clinical outcome of haplotype-mismatched stemcell transplantation. Here, donor NK subsets protect against acute myeloid leukemia (AML) relapse through missing self recognition of donor HLA-C allele groups (C1 or C2) and/or Bw4 epitope. These studies were subsequently extended by trials investigating the antileukemia effects of adoptively transferred haplotype-mismatched NK cells in non-transplant settings. Other mechanisms have been found to induce clinically relevant NK cell alloreactivity in transplantation, e.g., post-reconstitution functional reversal of anergic NK cells. More recently, activating KIR came into the spotlight for their potential ability to directly activate donor NK cells through in vivo recognition of HLA or other ligands. Novel therapeutic monoclonal antibodies (mAb) may optimize NK-mediated effects. Examples include obinutuzumab (GA101), a glyco-engineered anti-CD20 mAb with increased affinity for the FcγRIIIA receptor, enhancing antibody-dependent cellular cytotoxicity; lirilumab (IPH2102), a first-in-class NK-specific checkpoint inhibitor, blocking the interaction between the major KIR and cognate HLA-C antigens; and elotuzumab (HuLuc63), a humanized monoclonal antibody specific for SLAMF7, whose anti-myeloma therapeutic effects are partly due to direct activation of SLAMF7-expressing NK cells. In addition to conventional antibodies, NK cell-targeted bispecific (BiKEs) and trispecific (TriKEs) killer engagers have also been developed. These proteins elicit potent effector functions by binding target ligands (e.g., CD19, CD22, CD30, CD133, HLA class II, EGFR) on one arm and NK receptors on the other. An additional innovative approach to direct NK cell activity is genetic reprogramming with chimeric antigen receptors (CAR). To date, primary NK cells and the NK92 cell line have been engineered with CAR specific for antigens expressed on multiple tumors. Encouraging preclinical results warrant further development of this approach. This Research Topic welcomes contributions addressing mechanisms of NK-mediated activation in response to disease as well as past and contemporary strategies to enhance NK mediated reactivity through control of the interactions between NK receptors and their ligands.Tailoring NK Cell Receptor-Ligand InteractionsMedicinebicsscBispecific antibodiesCancerCheckpoint inhibitorsChimeric antigen receptorsImmune evasionImmunotherapyNatural killer cellsNK receptorsTransplantationMedicineGianfranco Pittariauth1292349Antoine ToubertauthUlrike KoehlauthBOOK9910346737203321Tailoring NK Cell Receptor-Ligand Interactions: an Art in Evolution. 2nd Edition3022201UNINA04764nam 2201513z- 450 9910367738403321202102113-03921-835-2(CKB)4100000010106333(oapen)https://directory.doabooks.org/handle/20.500.12854/50000(oapen)doab50000(EXLCZ)99410000001010633320202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Impact of Caffeine and Coffee on Human HealthMDPI - Multidisciplinary Digital Publishing Institute20191 online resource (322 p.)3-03921-834-4 The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.). Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.Biology, life sciencesbicssc24-h dietary recallaccidental deathadenosineadenosine receptorADORA2Aadultageagingalcohol consumptionanxietyassisted reproduction techniquesbehaviorbiasbiomarkerscaffeineCaffeinecaffeine intakecaffeine intoxicationcaffeine metabolismcardiovascular diseasecausalitycausationchlorogenic acidschocolateclinical pregnancycoffeecoffee consumptioncognitioncognitionscognitivecohort studyconsumptioncoronary artery diseasecountryCYP1A2cytochrome P450depressiondid not responddipyridamoleenergy drinksepidemiological methodsepidemiologyergogenicergogenic aidEuropean Prospective Investigation into Cancer and Nutritionexerciseexpectancygene expressiongene-diet interactiongenetic epidemiologyguidelineshealthhearingHIV-HCV co-infectionimplantationindividual responsesintoxicationlipidomicslipidslive birthliver fibrosislongevitylysophosphatidylcholinemateMendelian RandomizationmoodmRNAmyocardial perfusionn/aNADH dehydrogenasepharmacogenomicspharmacological ergogenic aidphenolicplacebopolymorphismpopulationpregnancyprotectionpublic policyregadenosonrespondersrisk factorssafetyserum chloride levelssexsodasportSuicidesupplementsystematic reviewteathe Norwegian Women and Cancer Cohort (NOWAC)time trial performancetinnitustranscriptomicstrialwhole-bloodwineBiology, life sciencesCornelis Marilynauth1292557Bamia ChristinaauthBOOK9910367738403321The Impact of Caffeine and Coffee on Human Health3022390UNINA04103nam 2201177z- 450 991055752230332120220111(CKB)5400000000044356(oapen)https://directory.doabooks.org/handle/20.500.12854/76637(oapen)doab76637(EXLCZ)99540000000004435620202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRemote Sensing Monitoring of Land Surface Temperature (LST)Basel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (337 p.)3-0365-1428-7 3-0365-1427-9 This book is a collection of recent developments, methodologies, calibration and validation techniques, and applications of thermal remote sensing data and derived products from UAV-based, aerial, and satellite remote sensing. A set of 15 papers written by a total of 70 authors was selected for this book. The published papers cover a wide range of topics, which can be classified in five groups: algorithms, calibration and validation techniques, improvements in long-term consistency in satellite LST, downscaling of LST, and LST applications and land surface emissivity research.Remote Sensing Monitoring of Land Surface Temperature Environmental science, engineering & technologybicsscair temperatureAMSR2annual cycle parametersBayesian Maximum EntropyBSRNcloudy sky LSTCopernicusdata fusiondaytime LSTDEMdisaggregationdownscalingDownscalingdronesemissivity box methodevapotranspirationfield-scaleFourier transform infrared spectrometerGK2AHimalayahyperspectral thermal infraredinterpolationland surface emissivityland surface emissivity (LSE)land surface temperatureland surface temperature (LST)Land Surface Temperature (LST)LandsatLandsat 8LSA-SAFLSTLST from GOES satellitesmachine-learningmeasurement uncertaintiesMODISmono window algorithmn/anighttime LSTnoisephysical modelportable spectrometerradiative transfer equationrandom forestsatellite retrievals of LSTsensitivity analysisSentinel 2Sentinel-2Sentinel-3single channel algorithmsingle-channel algorithmspatial averaging biasesspectral smoothnesssplit window algorithmsplit-window algorithmsplit-window methodstray light correctionSURFRAD datatemperature-emissivity separationthermalthermal infraredthermal remote sensingTIRStopographyunmanned aerial vehiclesvalidationEnvironmental science, engineering & technologySánchez Juan Manueledt1303779Coll CésaredtNiclòs RaqueledtSánchez Juan ManuelothColl CésarothNiclòs RaquelothBOOK9910557522303321Remote Sensing Monitoring of Land Surface Temperature (LST)3027209UNINA