04045nam 22007575 450 99654795650331620230810180808.09783031213915(electronic bk.)978303121390810.1007/978-3-031-21391-5(MiAaPQ)EBC30545029(Au-PeEL)EBL30545029(OCoLC)1379437660(DE-He213)978-3-031-21391-5(BIP)085993125(PPN)270617914(EXLCZ)992670704880004120230515d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierBioinformatic and Statistical Analysis of Microbiome Data[electronic resource] From Raw Sequences to Advanced Modeling with QIIME 2 and R /by Yinglin Xia, Jun Sun1st ed. 2023.Cham :Springer International Publishing :Imprint: Springer,2023.1 online resource (716 pages)Print version: Xia, Yinglin Bioinformatic and Statistical Analysis of Microbiome Data Cham : Springer International Publishing AG,c2023 9783031213908 Includes bibliographical references and index.Chapter 1. Introduction to Linux and Unix -- Chapter 2. Introduction to R, Rstudio -- Chapter 3. Bioinformatic Analysis of Next-Generation Sequencing -- Chapter 4. Bioinformatic Analysis of Metagenomics -- Chapter 5. Alpha Diversity -- Chapter 6. Beta Diversity -- Chapter 7. Differential Abundance Analysis -- Chapter 8. Analyzing Zero-Inflated Microbiome Data -- Chapter 9. Compositional Analysis of Microbiome Data -- Chapter 10. Longitudinal Data Analysis of Microbiome -- Chapter 11. Meta-analysis of Microbiome Data (optional).This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research. Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.BioinformaticsBiometryBig dataMathematical statisticsData processingBiotechnologyBiomedical engineeringBioinformaticsBiostatisticsBig DataStatistics and ComputingBiotechnologyBiomedical Engineering and BioengineeringMicrobiologyScienceBioinformatics.Biometry.Big data.Mathematical statisticsData processing.Biotechnology.Biomedical engineering.Bioinformatics.Biostatistics.Big Data.Statistics and Computing.Biotechnology.Biomedical Engineering and Bioengineering.576Xia Yinglin767992Sun JunMiAaPQMiAaPQMiAaPQ996547956503316Bioinformatic and Statistical Analysis of Microbiome Data3430601UNISA