00878nam0-22003131i-450-99000102578040332120040517143833.0000102578FED01000102578(Aleph)000102578FED0100010257820020001d--------km-y0itay50------bafraAlgèbre et analyse linéairespar A. Lichnerowiczpréface de G. Darmois2ème ed. rév.ParisMasson1970AlgebraTeoria delle equazioniCalcolo vettoriale512Lichnerowicz,André335054Darmois,Georges<1888-1960>ITUNINARICAUNIMARCBK99000102578040332110-038F2089FI1FI1Algèbre et analyse linéaires103793UNINA05512nam 2200721Ia 450 991046230560332120200520144314.00-19-932281-31-280-67997-297866136569020-19-984259-0(CKB)2670000000203386(EBL)931256(OCoLC)794664537(SSID)ssj0000621025(PQKBManifestationID)11926329(PQKBTitleCode)TC0000621025(PQKBWorkID)10616113(PQKB)10478850(StDuBDS)EDZ0000126993(MiAaPQ)EBC931256(WaSeSS)Ind00029637(Au-PeEL)EBL931256(CaPaEBR)ebr10569236(CaONFJC)MIL365690(EXLCZ)99267000000020338620110615d2012 uy 0engur|n|---|||||txtccrJasper's basic mechanisms of the epilepsies[electronic resource] /edited by Jeffrey L. Noebels ... [et al.]4th ed.Oxford ;New York Oxford University Pressc20121 online resource (1258 p.)Contemporary neurology series ;80Description based upon print version of record.0-19-974654-0 Includes bibliographical references and index.Cover; Contents; Contributors; SECTION 1 INTRODUCTION; 1. THE NEXT DECADE OF RESEARCH IN THE BASIC MECHANISMS OF THE EPILEPSIES; SECTION 1: INTRODUCTION; SECTION 2: FUNDAMENTALS OF NEURONAL EXCITABILITY RELEVANT TO SEIZURES AND EPILEPSY; SECTION 3: MECHANISMS OF SEIZURE SUSCEPTIBILITY AND EPILEPTOGENESIS; SECTION 4: EPILEPSY GENES AND DEVELOPMENT; SECTION 5: EPILEPSY THERAPEUTICS; CLOSING SUMMARY; 2. HERBERT H. JASPER AND THE BASIC MECHANISMS OF THE EPILEPSIES; THE EARLY YEARS; WORK AT THE MONTREAL NEUROLOGICAL INSTITUTE; THE FOUNDING OF IBRO AND THE BME PROJECTMOVING TO THE OTHER SIDE OF THE MOUNTAIN (MONT ROYAL, OF COURSE!)HERBERT JASPER'S LATE YEARS; APPENDIX: ORIGINAL CURRICULUM VITAE OF DR. H. JASPER, DATED APPROXIMATELY 1954; 3. WHY-AND HOW-DO WE APPROACH BASIC EPILEPSY RESEARCH?; WHAT DO WE MEAN BY "BASIC" RESEARCH?; WHAT CAN WE ACCOMPLISH BY ENGAGING IN BASIC RESEARCH?; WHY DO BASIC EPILEPSY RESEARCH?; HOW DO WE CHOOSE AND PRIORITIZE RESEARCH GOALS?; WHAT APPROACHES-CONCEPTUAL OR TECHNICAL-ARE LIKELY TO YIELD SIGNIFICANT RESULTS?; CONCLUDING THOUWGHTS; SECTION 2 FUNDAMENTALS OF NEURONAL EXCITABILITY RELEVANT TO SEIZURES AND EPILEPSY4. VOLTAGE-GATED NA[sup(+)] CHANNELS: STRUCTURE, FUNCTION, AND PATHOPHYSIOLOGYNA[sup(+)] CHANNEL SUBUNIT STRUCTURE; Na[sup(+)] CHANNEL GENES; MOLECULAR BASIS OF Na[sup(+)] CHANNEL FUNCTION; THREE-DIMENSIONAL STRUCTURE OF Na[sup(+)] CHANNELS; EXPRESSION, LOCALIZATION, AND FUNCTION OF Na[sup(+)] CHANNEL SUBTYPES IN THE NERVOUS SYSTEM; Na[sup(+)] CHANNEL PHARMACOLOGY; Na[sup(+)] CHANNEL AND EPILEPSY; GENETIC Na[sup(+)] CHANNELOPATHIES; FUTURE DEVELOPMENTS AND CHALLENGES; 5. POTASSIUM CHANNELS (INCLUDING KCNQ) AND EPILEPSYK[sup(+)] CHANNELS: A DIVERSE SUPERFAMILY DERIVED FROM AN EXTRAORDINARILY USEFUL TEMPLATEKCNQ CHANNELS: FROM CHANNELOPATHY TO NOVEL THERAPY; KCNQ CHANNELS AND BEYOND: PROSPECTS FOR FUTURE POTASSIUM CHANNEL STUDIES IN EPILEPSY RESEARCH; 6. VOLTAGE-GATED CALCIUM CHANNELS IN EPILEPSY; CALCIUM CHANNEL NOMENCLATURE; CALCIUM CHANNEL BIOPHYSICAL PROPERTIES; CALCIUM CHANNELS AND EXCITABILITY; CALCIUM CHANNELS IN ABSENCE EPILEPSY; CALCIUM CHANNELS IN TEMPORAL LOBE/COMPLEX PARTIAL EPILEPSY; CALCIUM CHANNELS IN GENERALIZED CONVULSIVE SEIZURES; CONCLUSIONS7. HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED (HCN) ION CHANNELOPATHY IN EPILEPSYHCN CHANNEL BIOPHYSICAL PROPERTIES; HCN CHANNEL EFFECTS ON NEURONAL EXCITABILITY; CONTRIBUTION OF HCN CHANNELS TO EPILEPSY; CONCLUSIONS; 8. PHASIC GABA[sub(A)]-MEDIATED INHIBITION; GABA[sub(A)]-MEDIATED IPSCS: PRESYNAPTIC REGULATION; DYNAMICS OF GABA TRANSIENTS IN THE SYNAPTIC CLEFT; GABA[sub(A)]-MEDIATED IPSCS: POSTSYNAPTIC REGULATION; FUTURE PERSPECTIVES; 9. TONIC GABA[sub(A)] RECEPTOR-MEDIATED SIGNALING IN EPILEPSY; GABA[sub(A)] RECEPTOR SUBTYPES UNDERLYING TONIC CONDUCTANCESFUNCTIONS OF TONIC GABA[sub(A)] RECEPTOR CURRENTSH.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a ""better understanding of the epilepsies and seek more rational methods of their prevention and treatment."" Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it shouContemporary neurology series ;80.EpilepsyConvulsionsElectronic books.Epilepsy.Convulsions.616.8/53Jasper Herbert H(Herbert Henri),1906-1999.860422Noebels Jeffrey L860423MiAaPQMiAaPQMiAaPQBOOK9910462305603321Jasper's basic mechanisms of the epilepsies1919752UNINA02841nam 2200409 450 99654031510331620230811124402.03-7489-3985-X(CKB)5710000000162172(NjHacI)995710000000162172(EXLCZ)99571000000016217220230811d2023 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierFuture Regulation of Cross-Border Audiovisual Content Dissemination A Critical Analysis of the Current Regulatory Framework for Law Enforcement under the EU Audiovisual Media Services Directive and the Proposal for a European Media Freedom Act /Mark D. Cole, Christina EtteldorfBaden-Baden :Nomos,2023.1 online resource (268 pages)Schriftenreihe Medienforschung der Landesanstalt für Medien NRW ;843-7560-0651-4 Includes bibliograhical references.Titelei/Inhaltsverzeichnis -- Executive Summary -- Zusammenfassung -- List of Abbreviations -- A. Introduction -- B. Challenges of a Cross-Border Media Environment in the EU -- C. The Audiovisual Media Services Directive (AVMSD): The Status Quo -- D. The Institutional Dimension: AVMSD and Beyond -- E. Applying the Findings to the Illustrative Scenarios and Gaps Identified -- F. Approaches and National Solutions Concerning Current Challenges -- G. Conclusion: On the Way to Enhanced Efficiency and a Modernised Regulatory Framework -- Bibliography.Die Realität der grenzüberschreitenden Verbreitung audiovisueller Inhalte In Europa birgt steigende Gefahren für Grundrechte und Werte der EU. Es stellt sich die Frage, wie diesen in einem komplexer werdenden Netzwerk sektoraler Rechtsakte der EU mit unterschiedlichen institutionellen Systemen effektiv begegnet werden kann. Die Studie analysiert den geltenden Rechtsrahmen für die grenzüberschreitende Verbreitung audiovisueller Inhalte mit Fokus auf dem Herkunftslandmechanismen der AVMD-Richtlinie und leitet daraus Herausforderungen für die Rechtsdurchsetzung ab. Diese werden mit Ansätzen aus anderen Rechtsakten wie dem vorgeschlagenen European Media Freedom Act (EMFA) verglichen, bevor mögliche Lösungsansätze vorgeschlagen werden.Schriftenreihe Medienforschung der Landesanstalt für Medien Nordrhein-Westfalen :84.Audio-visual materialsAudio-visual materials.371.33Cole Mark D.1972-1371928Etteldorf ChristinaNjHacINjHaclBOOK996540315103316Future Regulation of Cross-Border Audiovisual Content Dissemination3420399UNISA