05618nam 2200661 450 99642633830331620200520144314.0(CKB)2670000000612568(EBL)2037828(SSID)ssj0001534305(PQKBManifestationID)12608986(PQKBTitleCode)TC0001534305(PQKBWorkID)11496053(PQKB)10316915(MiAaPQ)EBC2037828(Au-PeEL)EBL2037828(CaPaEBR)ebr11049158(CaONFJC)MIL776949(OCoLC)908670583(EXLCZ)99267000000061256820150509h20152015 uy 0engur|n|---|||||txtccrRegenerative engineering of musculoskeletal tissues and interfaces /edited by Syam P. Nukavarapu, Joseph W. Freeman and Cato T. Laurencin ; contributors, K. A. Athanasiou [and fifty seven others]Amsterdam, [Netherlands] :Woodhead Publishing,2015.©20151 online resource (463 p.)Woodhead Publishing Series in Biomaterials ;Number 98Description based upon print version of record.1-78242-314-1 1-78242-301-X Includes bibliographical references at the end of each chapters and index.Front Cover; Related titles; Regenerative Engineering of Musculoskeletal Tissues and Interfaces; Copyright; Dedication; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Part One - Basic elements of musculoskeletal tissue engineering; 1 - Biomaterials and scaffolds for musculoskeletal tissue engineering; 1.1 Introduction; 1.2 Biomaterials; 1.3 Physical property requirements; 1.4 Scaffolds for musculoskeletal tissue engineering; 1.5 Conclusion and future directions; Acknowledgments; References; 2 - Cells for musculoskeletal tissue engineering; 2.1 Introduction2.2 Postnatal progenitor cells for musculoskeletal tissue engineering2.3 Prenatal progenitor cells for musculoskeletal tissue engineering; 2.4 Summary; Acknowledgments; References; 3 - Growth factors for musculoskeletal tissue engineering; 3.1 Introduction; 3.2 Origin and development of musculoskeletal tissues; 3.3 Molecular regulation of musculoskeletal system development; 3.4 Growth factor-based musculoskeletal tissue regeneration; 3.5 Current approaches for spatiotemporal control of growth factors; 3.6 Future directions; Acknowledgments; References4 - Mechanical forces in musculoskeletal tissue engineering4.1 Introduction; 4.2 Mechanical forces in guiding differentiation and extracellular matrix production; 4.3 Mechanical stimuli for tissue regeneration; 4.4 Methods of introducing mechanical stimuli; References; Part Two - Individual musculoskeletaltissues; 5 - Bone tissue engineering; 5.1 Introduction; 5.2 Traditional concepts in bone tissue engineering; 5.3 Current and new strategies for engineered bone: discussion and examples; 5.4 Bone tissue engineering challenges and a vision for the future5.5 The development challenges of an engineered bone productAcknowledgments; References; 6 - Cartilage tissue engineering; 6.1 Introduction; 6.2 Cartilage anatomy, physiology, and injury; 6.3 Current treatment options; 6.4 Tissue engineering considerations; 6.5 Conclusions; References; 7 - Ligament tissue engineering; 7.1 Introduction; 7.2 Ligament composition and structure; 7.3 Ligament mechanical properties; 7.4 Ligament injuries and their current clinical outcomes; 7.5 Options for surgical ligament replacement; 7.6 Summary; References; 8 - Tendon tissue engineering; 8.1 Introduction8.2 Tendon structure and function8.3 Tendon injury and degeneration; 8.4 Tendon healing; 8.5 Current treatment: the traditional approach; 8.6 Tissue engineering approach; 8.7 Scaffolds; 8.8 Materials selection; 8.9 Nanofibers; 8.10 Mechanical stimulation; 8.11 Cells; 8.12 Growth factors; 8.13 Gene therapy; 8.14 Future trends; 8.15 Conclusions; Acknowledgments; References; 9 - Meniscus tissue engineering; 9.1 Structure, anatomy, and function of the meniscus; 9.2 Meniscus injury and repair; 9.3 Meniscus replacement; 9.4 Conclusions; References; 10 - Muscle tissue engineering; 10.1 Introduction10.2 Skeletal muscle tissue Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cWoodhead Publishing series in biomaterials ;Number 98.Tissue engineeringRegenerative medicineElectronic books.Tissue engineering.Regenerative medicine.612.028Nukavarapu Syam P.Freeman Joseph W.Laurencin Cato T.Athanasiou K. A.MiAaPQBOOK996426338303316Regenerative engineering of musculoskeletal tissues and interfaces2184532UNISA