05154nam 2200613 450 99642633770331620201221190235.00-12-417115-X(CKB)3710000000085686(EBL)1632055(OCoLC)870949356(SSID)ssj0001161614(PQKBManifestationID)11651155(PQKBTitleCode)TC0001161614(PQKBWorkID)11128693(PQKB)11286612(MiAaPQ)EBC1632055(PPN)199262276(EXLCZ)99371000000008568620140306h20142014 uy 0engur|n|---|||||txtccrKey chiral auxiliary applications /Gregory Roos2nd ed.Waltham, [Massachusetts] ;Amsterdam, The Netherlands :Academic Press,2014.©20141 online resource (1271 p.)Description based upon print version of record.0-12-417034-X Includes bibliographical references.Front Cover; Key Chiral Auxiliary Applications; Copyright; CONTENTS; ACKNOWLEDGEMENTS; FOREWORD; PREFACE TO THE 2ND EDITION; ABBREVIATIONS; 1.INTRODUCTION; 1.1. BACKGROUND; 1.2. THE CHIRAL AUXILIARY APPROACH; 1.3. THIS COLLECTION; REFERENCES; 2.ALKYLATION AND RELATED REACTIONS I; 2.1 ALLYL AND BENZYL RELATED CARBANIONS; 2.2 ALLENIC ETHER TANDEM ACYLATION-CYCLIZATION; 2.3 ALDEHYDE DERIVED NUCLEOPHILES; 2.4 KETONE DERIVED NUCLEOPHILES; 2.5 ALDEHYDE AND KETONE ENOLATES WITH AUXILIARY-CONTAINING ELECTROPHILES; REFERENCES; 3.ALKYLATION AND RELATED REACTIONS II3.1 α-ALKYLATION OF CARBOXYLIC ACID DERIVED NUCLEOPHILESREFERENCES; 4.ALKYLATION AND RELATED REACTIONS III; 4.1 α-ALKYLATION OF -HETEROATOM SUBSTITUTED ACID DERIVATIVES; 4.2 α-ALKYLATION OF CYCLIC CARBOXYLIC ACID DERIVATIVES; REFERENCES; 5.ALKYLATION AND RELATED REACTIONS IV; 5.3 α-HYDROXYLATION OF ACID DERIVATIVES; 5.1 α-ACYLATION OF ACID DERIVATIVES; 5.2 α-AMINATION OF ACYL DERIVATIVES; 5.4 α-SILYLATION, α-THIOLATION, AND α-SELENATION OF ACID DERIVATIVES; 5.5 α-HALOGENATION OF ACID DERIVATIVES; 5.6 REACTION OF PHOSPHORIC ACID DERIVATIVES WITH ELECTROPHILES5.7 α-ALKYLATION OF SULFONIC ACID DERIVATIVES5.8 AROMATIC SUBSTITUTION; 5.9 NUCLEOPHILIC ALLYLIC SUBSTITUTION; 5.10 MISCELLANEOUS REACTIONS; REFERENCES; 6.ELECTROPHILIC RELATED ADDITION TO C=C; 6.1 REDUCTION AND RELATED REACTIONS; 6.2 ADDITION OF HALO-CONTAINING ADDENDS; 6.3 BISAMINATION; 6.4 ADDITION OF OXY-ADDENDS; 6.5 CYCLOPROPANATION; 6.6 CYCLOPROPENATION; 6.7 AZIRIDINATION; 6.8 ALKOXYSELENATION; 6.9 RADICAL ADDITION; REFERENCES; 7.CONJUGATE ADDITION I; 7.1 AUXILIARY ON DONOR NUCLEOPHILE - SIMPLE ADDITION; 7.2 AUXILIARY ON DONOR NUCLEOPHILE - TANDEM ADDITION; REFERENCES8.CONJUGATE ADDITION II8.1 AUXILIARY ON ACCEPTOR α,β-UNSATURATED SYSTEM - SIMPLE ADDITION; REFERENCES; 9.CONJUGATE ADDITION III; 9.1 α,β-UNSATURATED ACYL DERIVATIVES - ADDITION OF HETERONUCLEOPHILES; 9.2 OTHER ACTIVATED SYSTEMS; 9.3 INTRAMOLECULAR REACTIONS; 9.4 AUXILIARY ON α,β-UNSATURATED SYSTEM - TANDEM ADDITION OFCARBON NUCLEOPHILES; 9.5 AUXILIARY ON ACCEPTOR α,β-UNSATURATED SYSTEM - TANDEM ADDITION OFHETERONUCLEOPHILES; 9.6 AUXILIARY ON ACCEPTOR α,β-UNSATURATED SYSTEM - RADICAL ADDITION; 9.7 NUCLEOPHILIC ADDITION TO TRANSITION-METAL ALKENE/ARENE COMPLEXES; REFERENCES10.ADDITION TO C=N BONDS10.1 REDUCTION OF IMINES, IMINIUM IONS, HYDRAZONES AND OXIMES; 10.2 NUCLEOPHILIC ADDITION; 10.3 RADICAL ADDITION; 10.4 UGI COUPLING; REFERENCES; 11.ADDITION TO C=O BONDS I; 11.1 REDUCTION; 11.2 WITTIG & RELATED OLEFINATION; 11.3 ADDITION OF ORGANOMETALLIC AND RELATED REAGENTS; REFERENCES; 12.ADDITION TO C=O BONDS II; 12.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); REFERENCES; 13.ADDITION TO C=O BONDS III; 13.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); 13.2 TANDEM REACTIONS; 13.3 RADICAL REACTIONS; REFERENCES; 14. CYCLOADDITIONS I14.1 [2+2]-CYCLOADDITIONSKey Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of resulAsymmetric synthesisEnantioselective catalysisEnantiomersElectronic books.Asymmetric synthesis.Enantioselective catalysis.Enantiomers.547Roos Gregory872485MiAaPQBOOK996426337703316Key chiral auxiliary applications2371770UNISA