05209nam 2200625Ia 450 991083047610332120230721030217.01-280-92168-497866109216833-527-61094-43-527-61095-2(CKB)1000000000376507(EBL)481955(OCoLC)173136985(SSID)ssj0000146429(PQKBManifestationID)11137435(PQKBTitleCode)TC0000146429(PQKBWorkID)10183086(PQKB)10041352(MiAaPQ)EBC481955(EXLCZ)99100000000037650720061204d2007 uy 0engur|n|---|||||txtccrEnantioselective organocatalysis[electronic resource] reactions and experimental procedures /edited by Peter I. DalkoWeinheim Wiley-VCH ;Chichester John Wiley [distributor]20071 online resource (563 p.)Description based upon print version of record.3-527-31522-5 Includes bibliographical references and index.Enantioselective Organocatalysis; Contents; Preface; List of Contributors; List of Abbreviations; 1 Asymmetric Organocatalysis: A New Stream in Organic Synthesis; 1.1 Introduction; 1.2 Historical Background; 1.3 Catalysts; 1.3.1 Privileged Catalysts; 1.3.1.1 Proline [7k, 56]; 1.3.1.2 Cinchona Alkaloids [61]; 1.3.1.3 TADDOLs and Derivatives [63]; 1.3.1.4 Binaphthol Derivatives; 1.4 Reaction Types; 1.4.1 Covalent Catalysis; 1.4.2 Non-Covalent Organocatalysis; 1.5 How This Book is Organized; References and Notes; 2 Enamine Catalysis; 2.1 Aldol and Mannich-Type Reactions; 2.1.1 Introduction2.1.2 Aldol Reactions2.1.2.1 Aldol Reactions of Alkyl Ketone Donors; 2.1.2.2 Aldol Reactions of α-Oxyketone Donors; 2.1.2.3 Aldol Reactions of Aldehyde Donors; 2.1.2.4 Aldol Reactions with Ketone Acceptors; 2.1.2.5 Intramolecular Aldol Reactions; 2.1.2.6 Mechanism and Transition States of Aldol Reactions and Effects of Water on Aldol Reactions; 2.1.2.7 Catalyst Recycling; 2.1.2.8 Catalyst Development Strategies; 2.1.3 Mannich Reactions; 2.1.3.1 Mannich-Type Reactions of Aldehyde Donors with Glyoxylate Imines; 2.1.3.2 Mannich-Type Reactions of Aldehyde Donors with Other Preformed Imines2.1.3.3 Three-Component Mannich Reactions using Aldehyde Donors2.1.3.4 Mannich-Type Reactions of Ketone Donors; References; 2.2 α-Heteroatom Functionalization; 2.2.1 Introduction; 2.2.2 Direct α-Amination of Aldehydes and Ketones; 2.2.3 Direct α-Amination of α-Cyanoacetates and β-Dicarbonyl Compounds; 2.2.4 Direct α-Oxygenation Reactions of Aldehydes and Ketones; 2.2.5 Direct α-Oxygenation Reactions of β-Ketoesters; 2.2.6 Direct α-Halogenation Reactions of Aldehydes and Ketones; 2.2.6.1 Direct α-Fluorination of Aldehydes; 2.2.6.2 Direct α-Fluorination of β-Ketoesters2.2.6.3 Direct α-Chlorination of Aldehydes and Ketones2.2.6.4 Direct α-Chlorination of β-Ketoesters; 2.2.6.5 Direct α-Bromination of Aldehydes and Ketones; 2.2.7 Direct α-Sulfenylation of Aldehydes; 2.2.8 Direct α-Sulfenylation of Lactones, Lactams, and β-Diketones; 2.2.9 Direct α-Selenation of Aldehydes and Ketones; References; 2.3 Direct Conjugate Additions via Enamine Activation; 2.3.1 Introduction; 2.3.2 Factors Determining the Stereoselectivity of the Organocatalytic Conjugate Additions; 2.3.3 Addition of Ketones to Nitroolefins and Alkylidene Malonates; 2.3.3.1 Proline2.3.3.2 Pyrrolidine Amines and Pyrrolidine Amine Salts as Catalysts for Michael-Type Addition of Ketones to Activated Olefins2.3.3.3 Chiral Primary Amines; 2.3.3.4 Amine/Thiourea Catalysts; 2.3.4 Addition of Aldehydes to Nitroolefins and Alkylidene Malonates; 2.3.4.1 Aminopyrrolidine Catalysts; 2.3.4.2 Addition of Aldehydes and Ketones to Enones; 2.4 Conclusions; References; 3 Iminium Catalysis; 3.1 Introduction; 3.2 The Catalysis Concept of Iminium Activation; 3.3 Development of the ''First-Generation'' Imidazolidinone Catalysts3.4 Development of the ''Second-Generation'' Imidazolidinone CatalystsIn this reference leaders at the forefront of research provide an insight into one of the hottest topics in organic synthesis, focusing on the most important enantioselective reactions.Clearly structured, each entry begins with a concise introduction, including a mechanistic discussion of the reaction, followed by preparative guidelines for newcomers, such as carefully selected working procedures with critical notes for bench chemists, rules of thumb and tips and tricks.Enantioselective catalysisOrganic compoundsSynthesisEnantioselective catalysis.Organic compoundsSynthesis.541.395547.1395547.2Dalko Peter I1622280MiAaPQMiAaPQMiAaPQBOOK9910830476103321Enantioselective organocatalysis3965955UNINA01772nam 2200433Ia 450 99639745400331620240530122033.0(CKB)4940000000063041(EEBO)2240910726(OCoLC)9922973200971(EXLCZ)99494000000006304120040304d1633 uy 0engurbn#|||a|bb|txtrdacontentcrdamediacrrdacarrier[The balme of Gilead prepared for the sicke] [The whole is diuided into three partes: 1. The sicke mans sore. 2. The sicke mans salue. 3. The sicke mans song. /Published by Mr. Zacharie Boyd, preacher of Gods Word, at Glasogw [sic]. August.][Edinburgh Printed by Iohn Wreittoun1633][2+], 265 [i.e. 248] pTitle page lacking. Title and imprint conjectured by catalogers.Numerous errors in paging.The dedication is addressed to King Charles.Signatures: A-P⁸, Q⁴; conjectured t.p. and dedication to K. Charles may be cancels.Imperfect: t.p. lacking, faded and tightly bound, with loss of text.Reproduction of original in: National Library of Scotland.eebo-0097SickPrayer-books and devotionsEarly works to 1800Devotional literature, EnglishEarly works to 1800SickPrayer-books and devotionsDevotional literature, EnglishBoyd Zacharie1585?-1653.1001000Wreittoun John-1640,EBKEBKBOOK996397454003316The balme of Gilead prepared for the sicke2315727UNISA