01748nas 2200505-a 450 99621660840331620230217213020.0(DE-599)ZDB2511988-6(OCoLC)52907060(CKB)111088197764404(CONSER)--2004213710(EXLCZ)9911108819776440420030825a20029999 s-- aengurcnu||||||||txtrdacontentcrdamediacrrdacarrierGlobal media journal[American edition].Hammond, Ind. Dept. of Communication and Creative Arts, Purdue University Calumet[2002]-Wilmington, Delaware, USA Global Media Journal1 online resourceRefereed/Peer-reviewedTitle from title screen (publisher's Web site, viewed June 7, 2004).1550-7521 GMJGMJ-American editionMass mediaSocial aspectsPeriodicalsMass mediaPolitical aspectsPeriodicalsMass mediaPolitical aspectsfast(OCoLC)fst01011278Mass mediaSocial aspectsfast(OCoLC)fst01011303Periodicals.fastPeriodicals.lcgftMass mediaSocial aspectsMass mediaPolitical aspectsMass mediaPolitical aspects.Mass mediaSocial aspects.302Purdue University Calumet.Department of Communication and Creative Arts,Global Communication Association (Ind.),JOURNAL996216608403316Global media journal1982369UNISA04164nam 2200637 450 991081842680332120200520144314.01-118-64584-71-118-64567-7(CKB)3710000000088816(EBL)1632617(SSID)ssj0001111445(PQKBManifestationID)11701289(PQKBTitleCode)TC0001111445(PQKBWorkID)11129575(PQKB)10737756(OCoLC)870950338(MiAaPQ)EBC1632617(Au-PeEL)EBL1632617(CaPaEBR)ebr10838607(CaONFJC)MIL577404(PPN)179863908(EXLCZ)99371000000008881620130927h20142014 uy| 0engurcnu||||||||txtccrThe biostatistics of aging from Gompertzian mortality and to an index of aging-relatedness /Gilberto Levy, Bruce LevinHoboken, NJ :John Wiley & Sons Inc.,[2014]©20141 online resource (270 p.)Description based upon print version of record.1-118-64585-5 Includes bibliographical references and index.THE BIOSTATISTICS OF AGING: From Gompertzian Mortality to an Index of Aging-Relatedness; Copyright; CONTENTS; PREFACE AND ACKNOWLEDGMENT; 1 Introduction; 2 An Account of Gompertzian Mortality through Statistical and Evolutionary Arguments; 2.1 The Statistical Theory of Extreme Values; 2.1.1 Background to Results; 2.1.2 Original Results; 2.2 The Evolutionary Theory of Aging; 2.2.1 The Argument for Gompertzian Mortality; 2.2.2 Boundaries of the Argument; 3 The Argument against Gompertzian Mortality; 3.1 Departures from the Gompertz Model; 3.2 An Evolution-Based Model of Causation4 The Index of Aging-Relatedness 4.1 A Survival Mixture Model of the Gompertz and Weibull Distributions; 4.2 Definition and Interpretation of the Index of Aging-Relatedness; 4.3 The Survival Mixture Model and Competing Risks; 4.4 Estimation of the Model Parameters; 4.5 Illustrative Application: The Israeli Ischemic Heart Disease Study; 4.6 Precision of Estimation; 5 Discussion: Implications; 5.1 The Meaning of the Gompertz Parameter; 5.2 Age as a Risk Factor for Disease; 5.3 Are Aging-Related Diseases an Integral Part of Aging?; 5.4 Biological versus Chronological Aging5.5 The Public Health Notion of Compression of Morbidity 5.6 A Picture of Aging for the Twenty-First Century; APPENDIX A: PROOFS OF RESULTS IN SECTION 2.1.2 WITH SOME EXTENSIONS; APPENDIX B: DERIVATION OF HAMILTON'S EQUATION FOR THE FORCE OF NATURAL SELECTION ON MORTALITY; APPENDIX C: SOME PROPERTIES OF THE GOMPERTZ AND WEIBULL DISTRIBUTIONS; APPENDIX D: FIRST AND SECOND PARTIAL DERIVATIVES OF THE MIXTURE LOG-LIKELIHOOD FUNCTION; APPENDIX E: EXPECTATION-CONDITIONAL MAXIMIZATION(ECM) ALGORITHM; APPENDIX F: R PROGRAM; REFERENCES; AUTHOR INDEX; SUBJECT INDEXA practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtle notion-with consequential biomedical and public health relevance-of what it means for a condition to be related to aging. In this pursuit, the book presents a new quantitative method to examine the relative contributions of genetic and environmental factors to mortality and disease incidence in a population. With input frAgingStatistical methodsMortalityStatistical methodsLife spans (Biology)AgingStatistical methods.MortalityStatistical methods.Life spans (Biology)571.8/78Levy Gilberto1693338Levin Bruce A877330MiAaPQMiAaPQMiAaPQBOOK9910818426803321The biostatistics of aging4071045UNINA