06983nam 22008415 450 99621370020331620200629220339.03-319-08587-510.1007/978-3-319-08587-6(CKB)3710000000219386(SSID)ssj0001295963(PQKBManifestationID)11777923(PQKBTitleCode)TC0001295963(PQKBWorkID)11347777(PQKB)10299164(DE-He213)978-3-319-08587-6(MiAaPQ)EBC6303138(MiAaPQ)EBC5588044(Au-PeEL)EBL5588044(OCoLC)1066185085(PPN)179925555(EXLCZ)99371000000021938620140701d2014 u| 0engurnn#008mamaatxtccrAutomated Reasoning[electronic resource] 7th International Joint Conference, IJCAR 2014, Held as Part of the Vienna Summer of Logic, Vienna, Austria, July 19-22, 2014, Proceedings /edited by Stéphane Demri, Deepak Kapur, Christoph Weidenbach1st ed. 2014.Cham :Springer International Publishing :Imprint: Springer,2014.1 online resource (XXVIII, 528 p. 101 illus.)Lecture Notes in Artificial Intelligence ;8562Bibliographic Level Mode of Issuance: Monograph3-319-08586-7 From Reachability to Temporal Specifications in Cost-Sharing Games -- Electronic Voting: How Logic Can Help -- And-Or Tableaux for Fix point Logics with Converse: LTL, CTL, PDL and CPDL -- Unified Classical Logic Completeness: A Coinductive Pearl -- A Focused Sequent Calculus for Higher-Order Logic -- SAT-Based Decision Procedure for Analytic Pure Sequent Calculi -- A Unified Proof System for QBF Pre processing -- The Fractal Dimension of SAT Formulas -- A Gentle Non-disjoint Combination of Satisfiability Procedures -- A Rewriting Strategy to Generate Prime Implicates in Equational Logic -- Finite Quantification in Hierarchic Theorem Proving -- Computing All Implied Equalities via SMT-Based Partition Refinement -- Proving Termination of Programs Automatically with A Pro VE -- Locality Transfer: From Constrained Axiomatizations to Reachability Predicates -- Proving Termination and Memory Safety for Programs with Pointer Arithmetic -- QBF Encoding of Temporal Properties and QBF-Based Verification -- Introducing Quantified Cuts in Logic with Equality -- Quati: An Automated Tool for Proving Permutation Lemmas -- A History-Based Theorem Prover for Intuitionistic Propositional Logic Using Global Caching: IntHistGC System Description -- M lean CoP: A Connection Prover for First-Order Modal Logic -- Optimal Tableaux-Based Decision Procedure for Testing Satisfiability in the Alternating-Time Temporal Logic ATL+ -- dTL2: Differential Temporal Dynamic Logic with Nested Temporalities for Hybrid Systems -- Axioms vs Hypersequent Rules with Context Restrictions: Theory and Applications -- Clausal Resolution for Modal Logics of Confluence -- Implementing Tableau Calculi Using BDDs: BDDTab System Description -- Approximations for Model Construction -- A Tool That Incrementally Approximates Finite Satisfiability in Full Interval Temporal Logic -- StarExec: A Cross-Community Infrastructure for Logic -- Skeptik: A Proof Compression System -- Terminating Minimal Model Generation Procedures for Propositional Modal Logics -- Cool – A Generic Reasoner for Coalgebraic Hybrid Logics (System Description) -- The Complexity of Theorem Proving in Circumscription and Minimal Entailment -- Visibly Linear Temporal Logic -- Count and Forget: Uniform Interpolation of SHQ- Ontologies -- Coupling Tableau Algorithms for Expressive Description Logics with Completion-Based Saturation Procedures -- EL-ifying Ontologies -- The Bayesian Description Logic BEL -- OTTER Proofs in Tarskian Geometry -- NESCOND: An Implementation of Nested Sequent Calculi for Conditional Logics -- Knowledge Engineering for Large Ontologies with Sigma KEE 3.0.This book constitutes the refereed proceedings of the 7th International Joint Conference on Automated Reasoning, IJCAR 2014, held as part of the Vienna Summer of Logic, VSL 2014, in Vienna, Austria, in July 2014. IJCAR 2014 was a merger of three leading events in automated reasoning, namely CADE (International Conference on Automated Deduction), FroCoS (International Symposium on Frontiers of Combining Systems) and TABLEAUX (International Conference on Automated Reasoning with Analytic Tableaux and Related Methods). The 26 revised full research papers and 11 system descriptions presented together with 3 invited talks were carefully reviewed and selected from 83 submissions. The papers have been organized in topical sections on HOL, SAT and QBF, SMT, equational reasoning, verification, proof theory, modal and temporal reasoning, SMT and SAT, modal logic, complexity, description logics and knowledge representation and reasoning.Lecture Notes in Artificial Intelligence ;8562Mathematical logicComputer logicArtificial intelligenceSoftware engineeringComputer science—MathematicsNumerical analysisMathematical Logic and Formal Languageshttps://scigraph.springernature.com/ontologies/product-market-codes/I16048Logics and Meanings of Programshttps://scigraph.springernature.com/ontologies/product-market-codes/I1603XArtificial Intelligencehttps://scigraph.springernature.com/ontologies/product-market-codes/I21000Software Engineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/I14029Mathematics of Computinghttps://scigraph.springernature.com/ontologies/product-market-codes/I17001Numeric Computinghttps://scigraph.springernature.com/ontologies/product-market-codes/I1701XMathematical logic.Computer logic.Artificial intelligence.Software engineering.Computer science—Mathematics.Numerical analysis.Mathematical Logic and Formal Languages.Logics and Meanings of Programs.Artificial Intelligence.Software Engineering.Mathematics of Computing.Numeric Computing.004.015113Demri Stéphaneedthttp://id.loc.gov/vocabulary/relators/edtKapur Deepakedthttp://id.loc.gov/vocabulary/relators/edtWeidenbach Christophedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK996213700203316Automated Reasoning771895UNISA05037nam 2200649 a 450 991062611420332120200520144314.01-283-67084-41-78064-031-5(CKB)2670000000240871(EBL)1044650(OCoLC)813536564(SSID)ssj0000757551(PQKBManifestationID)12323569(PQKBTitleCode)TC0000757551(PQKBWorkID)10758942(PQKB)11600417(MiAaPQ)EBC1044650(EXLCZ)99267000000024087120120110d2012 uy 0engur|n|---|||||txtccrAntimicrobial drug discovery emerging strategies /edited by George Tegos and Eleftherios MylonakisWallingford, Oxfordshire, U.K. CABI20121 online resource (369 p.)Advances in molecular and cellular microbiology ;22Description based upon print version of record.1-84593-943-3 Includes bibliographical references and index.Emerging discovery strategies : an evolving necessity / Anthony R. Ball and George P. Tegos -- The antibiotic crisis / Arnold L. Demain and Jaroslav Spizek -- Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of escerichia coli and salmonella / Leonard Amaral ... [et al.] -- Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents / Sanjay M. Jachak ... [et al.] -- Fungal efflux-mediated resistance : from targets to inhibitors / Brian C. Monk ... [et al.] -- Vacuolar ATPase (V-ATPase) : a model proton pump for antifungal drug discovery -- Karlett J Parra -- Drug tolerance, persister cells and drug discovery / Kim Lewis -- Inhibition of quorum sensing as a novel antimicrobial strategy -- Gilles Brackman, Hans J. Nelis and Tom Coenye -- Filamentous temperature-sensitive mutant Z (FtsZ) protein as an antibacterial target / Jaroslaw M. Boberek ... [et al.] -- Lysostaphin : a silver bullet for staph / John F. Kokai-Kun -- Strategies to identify modified ribosomally synthesized antimicrobials -- Alan J. Marsh ... [et al.] -- QSAR based discovery of antimicrobial peptides active against multidrug resistant bacteria / Christopher D. Fjell ... [et al.] -- Acetyl-CoA carboxylase as a target for antibacterial development / Grover L. Waldrop -- Underexploited targets in LPS biogenenesis for the design of antibacterials / Laura Cipolla ... [et al.] -- Predicting and dissecting biomolecular interactions by information-driven docking / Panagiotis Kastritsis & Alexandre M.J.J Bonvin -- Anti-fungals and anti-fungal drug discovery / Richard Calderone ... [et al.] -- Pathosystematic studies and the rational design of antifungal interventions / Elaine M Bignell and Darius Armstrong-James -- In vivo high-throughput antimicrobial discovery screens utilizing caenorhabditis elegans as an alternative host / Jeffrey J. Coleman and Eleftherios Mylonakis -- Drosophila melanogaster as a versatile model for discovery of drugs effective against human microbe-induced infection and pathology / Yiorgos Apidianakis and Dimitrios P. Kontoyiannis -- Antimicrobial photosensitizers - harnessing the power of light to treat infections / Sulbha K Sharma, Tianhong Dai and Michael R Hamblin -- Nanoparticle platforms for antimicrobial therapy / David Trofa, Joshua D. Nosanchuk -- Antimicrobial activity of carbon nanotubes / Shaobin Liu, Yuan Chen.Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertAdvances in Molecular and Cellular MicrobiologyAnti-infective agentsDrugsDesignDiseasesAnimal modelsHigh throughput screeningMethodologyPhotosensitizing compoundsPharmacologyAnti-infective agents.DrugsDesign.DiseasesAnimal models.High throughput screeningMethodology.Photosensitizing compounds.Pharmacology.615.7/92Tegos George1267333Mylonakis Eleftherios1267334MiAaPQMiAaPQMiAaPQBOOK9910626114203321Antimicrobial drug discovery2980071UNINA