03576nam 2200637 a 450 99620695680331620230213211711.01-280-78407-597866136944610-470-72073-50-470-71842-0(CKB)1000000000688145(EBL)703912(OCoLC)797918492(SSID)ssj0000715489(PQKBManifestationID)11435131(PQKBTitleCode)TC0000715489(PQKBWorkID)10701713(PQKB)11341815(MiAaPQ)EBC703912(Au-PeEL)EBL703912(CaPaEBR)ebr10575664(CaONFJC)MIL369446(EXLCZ)99100000000068814519831122d1982 uy 0engur|n|---|||||txtccrSubstance P in the nervous system[electronic resource]London Pitman ;Summit, N.J., USA Distributed in North America by Ciba Pharmaceutical Co., Medical Education Administration19821 online resource (362 p.)Ciba Foundation symposium ;91"Editors: Ruth Porter (organizer) and Maeve O'Connor"--P. v.0-470-66408-8 0-272-79655-7 Includes bibliographical references and indexes.Substance P in the nervous system; Contents; Introduction; Chemical neurotransmission-yesterday and today; Role of substance P as a sensory transmitter in spinal cord and sympathetic ganglia; Discussion; Substance P in peripheral sensory processes; Discussion; Localization of substance P in neuronal pathways; Discussion; Distribution of substance P in brain and periphery and its possible role as a co-transmitter; Discussion; Regulation of substance P expression and metabolism in vivo and in vitro; Discussion; GENERAL DISCUSSION; Coexistence of transmittersSubstance P in nerve tissue in the gut Discussion; Biosynthesis, axonal transport and turnover of neuronal substance P; Discussion; Enzymic inactivation of substance P in the central nervous system; Discussion; Substance P receptors in the nervous system and possible receptor subtypes; Discussion; Relation of substance P to pain transmission: neurophysiological evidence; Discussion; Substance P in nociceptive sensory neurons; Discussion; If substance P fails to fulfil the criteria as a neurotransmitter in somatosensory afferents, what might be its function?; DiscussionModulation of cholinergic transmission by substance PDiscussion; The striatonigral substance P pathway and dopaminergic mechanisms; Discussion; Relation of substance P to stress and catecholamine metabolism; Discussion; Behavioural effects of substance P through dopaminergic pathways in the brain; Discussion; FINAL GENERAL DISCUSSION; Substance P antagonists; tumour cell lines and substance P; substance P and other tachykinins; substance P and clinical pain syndromes; substance P and neuronal systems; Index of contributors; Subject indexCiba Foundation symposium ;91.Substance PCongressesNeurologyCongressesSubstance PNeurology599/.0188Porter Ruth64811O'Connor Maeve284912MiAaPQMiAaPQMiAaPQBOOK996206956803316Substance P in the nervous system1963079UNISA