03456nam 22005894a 450 99620209840331620230721031252.01-281-06924-897866110692470-470-69197-20-470-76594-1(CKB)1000000000413182(EBL)320053(OCoLC)476116407(SSID)ssj0000117855(PQKBManifestationID)11145431(PQKBTitleCode)TC0000117855(PQKBWorkID)10051304(PQKB)11132353(MiAaPQ)EBC320053(EXLCZ)99100000000041318220070207d2007 uy 0engur|n|---|||||txtccrCardiovascular genetics and genomics for the cardiologist[electronic resource] /edited by Victor J. Dzau, Choong-Chin LiewMalden, Mass. Blackwell Futura20071 online resource (330 p.)Description based upon print version of record.1-4051-3394-5 Includes bibliographical references and index.The gene in the twenty-first century / Choong-Chin Liew, Victor J. Dzau -- Monogenic hypercholesterolemia / Ruth McPherson -- Hypertrophic cardiomyopathy / Ali J. Marian -- Dilated cardiomyopathy and other cardiomyopathies / Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus -- The long QT syndrome / Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima -- Atherosclerosis / Päivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew -- Heart failure / Markus Meyer, Peter VanBuren -- The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension / Kiat Tsong Tan, Choong-Chin Liew -- Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects / Ion S. Jovin, Frank J. Giordano -- Stem cell therapy for cardiovascular disease / Emerson C. Perin, Guilherme V. Silva -- Pharmacogenetics and personalized medicine / Julie A. Johnson, Issam Zineh -- The potential of blood-based gene profiling for disease assessment / Steve Mohr, Choon-Chin Liew.Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew - both pioneers in the area - help cardiologists understand: how cardiovascular genetics may remodel the way cardiovascular medicineCardiovascular systemDiseasesGenetic aspectsCardiovascular systemMolecular aspectsGenomicsCardiovascular systemDiseasesGenetic aspects.Cardiovascular systemMolecular aspects.Genomics.616.1/042616.1042Dzau Victor J873810Liew Choong-Chin873811MiAaPQMiAaPQMiAaPQBOOK996202098403316Cardiovascular genetics and genomics for the cardiologist1950675UNISA