03583nam 22007092 450 991045802570332120151005020621.01-107-22753-41-139-12489-71-283-29862-71-139-12342-497866132986211-139-00523-51-139-12833-71-139-11331-31-139-11767-X1-139-11550-2(CKB)2550000000055842(EBL)805536(OCoLC)768770477(SSID)ssj0000539799(PQKBManifestationID)11327622(PQKBTitleCode)TC0000539799(PQKBWorkID)10579907(PQKB)10188915(UkCbUP)CR9781139005234(MiAaPQ)EBC805536(Au-PeEL)EBL805536(CaPaEBR)ebr10502715(CaONFJC)MIL329862(EXLCZ)99255000000005584220141103d2011|||| uy| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierThe origins of AIDS /Jacques Pepin[electronic resource]Cambridge :Cambridge University Press,2011.1 online resource (xiv, 293 pages) digital, PDF file(s)Title from publisher's bibliographic system (viewed on 05 Oct 2015).0-521-18637-4 1-107-00663-5 Includes bibliographical references (p. 238-281) and index.Machine generated contents note: Introduction; 1. Out of Africa; 2. The source; 3. The timing; 4. The cut hunter; 5. Societies in transition; 6. The oldest trade; 7. Injections and the transmission of viruses; 8. The legacies of colonial medicine I: French Equatorial Africa and Cameroun; 9. The legacies of colonial medicine II: the Belgian Congo; 10. The other human immunodeficiency viruses; 11. From the Congo to the Caribbean; 12. The blood trade; 13. The globalisation; 14. Assembling the puzzle; 15. Epilogue: lessons learned.It is now thirty years since the discovery of AIDS but its origins continue to puzzle doctors and scientists. Inspired by his own experiences working as an infectious diseases physician in Africa, Jacques Pepin looks back to the early twentieth-century events in Africa that triggered the emergence of HIV/AIDS and traces its subsequent development into the most dramatic and destructive epidemic of modern times. He shows how the disease was first transmitted from chimpanzees to man and then how urbanization, prostitution, and large-scale colonial medical campaigns intended to eradicate tropical diseases combined to disastrous effect to fuel the spread of the virus from its origins in Léopoldville to the rest of Africa, the Caribbean and ultimately worldwide. This is an essential new perspective on HIV/AIDS and on the lessons that must be learnt if we are to avoid provoking another pandemic in the future.HIV infectionsAfricaHIV infectionsEtiologyAIDS (Disease)AfricaEmerging infectious diseasesAfricaHIV infectionsHIV infectionsEtiology.AIDS (Disease)Emerging infectious diseases362.196/97920096Pepin Jacques1958-1047546UkCbUPUkCbUPBOOK9910458025703321The origins of AIDS2475159UNINA05702nam 2200733Ia 450 991014134330332120230801221928.01-280-58737-797866136172001-118-29974-41-118-29975-21-118-29976-0(CKB)2670000000159879(EBL)866453(OCoLC)785731198(SSID)ssj0000640411(PQKBManifestationID)11439469(PQKBTitleCode)TC0000640411(PQKBWorkID)10611541(PQKB)10231144(MiAaPQ)EBC866453(Au-PeEL)EBL866453(CaPaEBR)ebr10538684(CaONFJC)MIL361720(EXLCZ)99267000000015987920120325d2012 uy 0engur|n|---|||||txtccrRecent advances in polyphenol researchVolume 3[electronic resource] /edited by Véronique Cheynier, Pascale Sarni-Manchado, Stéphane QuideauChichester, West Sussex Wiley-Blackwell20121 online resource (394 p.)Recent Advances in Polyphenol Research ;Volume 3Contains chapters by guest speakers at the 25th- International Conference on Polyphenols.1-4443-3746-7 Includes bibliographical references and index.Recent Advances in PolyphenolResearch; Contents; Contributors; Preface; 1 Plant Phenolics: A Biochemical and Physiological Perspective; 1.1 The general phenolic metabolism in plants; 1.2 Effect of non-freezing low temperature stress on phenolic metabolism in crop plants; 1.3 Plant phenolics as defence compounds; 1.3.1 Phenolic-mediated induced resistance of apples against fungal pathogens; 1.3.2 Contribution of vigna phenolics to plant protection against insects; 1.4 Diversion of carbon skeletons from primary to phenolic-related secondary metabolism1.4.1 Metabolic costs of adaptive responses to adverse environmental conditions1.4.2 Transduction pathway between nutrient depletion and enhanced polyphenol content; References; 2 Polyphenols: From Plant Adaptation to Useful Chemical Resources; 2.1 The emergence of phenolic metabolism and the adaptation of plants to a terrestrial environment; 2.2 The shikimate pathway: a complex and subtle interface between primary metabolism and phenolic metabolism; 2.2.1 Quinic acid, a specific component of higher plants2.2.2 The postchorismate branch of the shikimate pathway leading to phenylalanine: one or two metabolic routes in plants?2.2.2.1 Intracellular location of enzymes; 2.2.2.2 Complex and new regulatory mechanisms in the shikimate pathway; 2.3 Plant (poly)phenols: a diversified reservoir of useful chemicals; 2.3.1 The health-promoting properties of polyphenols; 2.3.2 A new time for lignocellulosics utilization through biotechnology; 2.3.2.1 Biomass pretreatment and enzymatic conversion of polysaccharides; 2.3.2.2 Lignins: degradation, bioconversion2.3.2.3 The fermentation step towards the production of bioalcohols2.3.2.4 Biorefinery pilot plants; 2.3.2.5 Quality and availability of the upstream resource; 2.3.2.6 Future prospects; 2.3.3 Chemical and catalytic valorization of polyphenols; 2.4 Concluding remarks; Acknowledgments; References; 3 Fifty Years of Polyphenol-Protein Complexes; 3.1 Introduction; 3.2 Precipitable complexes; 3.3 Soluble complexes; 3.4 Proline-rich proteins; 3.5 Mechanisms of binding; 3.6 Stoichiometry of binding; 3.7 Protein conformation; 3.8 Covalent tannin-protein complexes; 3.9 Conclusions; AcknowledgmentsReferences4 Chemistry of Flavonoids in Color Development; 4.1 Introduction; 4.2 Synthetic studies on anthocyanins toward polyacylated pigments; 4.2.1 Previously reported syntheses of anthocyanins; 4.2.2 Synthesis of anthocyanin using biomimetic oxidation; 4.2.3 Transformation of flavonol derivatives to anthocyanins via a flavenol glycoside; 4.3 Synthesis of copigments for studying blue color development; 4.3.1 Copigmentation in metalloanthocyanins; 4.3.2 Synthesis of glycosylated flavones; 4.3.3 Chiral recognition in metalloanthocyanin formation4.3.4 Synthesis of acylquinic acid derivatives for studies on hydrangea colorationPlant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins) are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents. Sponsored by Groupe Polyphénols, this publication, which is the third volume in this highly regarded RRecent advances in polyphenol research ;Volume 3.PolyphenolsCongressesBotanical chemistryCongressesPolyphenolsBotanical chemistry547.632572.2572/.2Cheynier Véronique994170Sarni-Manchado Pascale994171Quideau Stéphane994172International Conference on Polyphenols(25th :2010 :Montpellier, France)MiAaPQMiAaPQMiAaPQBOOK9910141343303321Recent advances in polyphenol research2276884UNINA01208nas 2200457-a 450 99619936620331620230522213016.01874-933X(DE-599)ZDB2395107-2(OCoLC)60623869(CKB)110978977973476(CONSER)--2007265280(EXLCZ)9911097897797347620050614a19469999 --- aengur|||||||||||txtrdacontentcrdamediacrrdacarrierKew bulletinLondon :H.M.S.O.<2019-> ;Switzerland :Springer Nature Switzerland AG1 online resourceRefereed/Peer-reviewed0075-5974 KBKEW BULLKew bull.BotanyPeriodicalsBotanyfast(OCoLC)fst00836869Periodicals.fastPeriodicals.lcgftBotany - GeneralBotanyBotany.580.7Royal Botanic Gardens, Kew.JOURNAL996199366203316Kew bulletin1998384UNISA