05596nam 2200709 450 99619769560331620230617040142.01-280-21311-697866102131150-470-75107-X1-4051-4777-6(CKB)1000000000415506(EBL)238396(OCoLC)61460296(SSID)ssj0000167757(PQKBManifestationID)11155419(PQKBTitleCode)TC0000167757(PQKBWorkID)10190783(PQKB)10930030(MiAaPQ)EBC238396(MiAaPQ)EBC4957949(Au-PeEL)EBL4957949(CaONFJC)MIL21311(OCoLC)1027156065(EXLCZ)99100000000041550620160820h20032003 uy 0engur|n|---|||||txtccrHandbook of laboratory animal management and welfare /Sarah Wolfensohn and Maggie Lloyd3rd ed.Oxford, England :Blackwell Publishing,2003.©20031 online resource (430 p.)Description based upon print version of record.1-4051-1159-3 Includes bibliographical references at the end of each chapters and index.""Handbook of Laboratory Animal Management and Welfare""; ""Contents""; ""Acknowledgements""; ""SECTION 1: GENERAL""; ""1 Education and training for the licence holder""; ""Introduction""; ""Attitudes""; ""Training""; ""Core competencies of personal licence holders""; ""Further information""; ""Websites""; ""2 The regulatory framework""; ""A brief history of the use of animals in research""; ""Legislation and animal use""; ""The animals (scientific procedures) act 1986""; ""Communication""; ""The ethics of using animals in experiments""; ""Statistics of animal usage""""Legislation controlling use of animals in""""Experiments in other countries""; ""Other relevant legislation in the uk""; ""Further information""; ""3 Health, safety and security""; ""Legal framework""; ""The hazards""; ""Miscellaneous health and safety hazards and risks""; ""Lone working""; ""Employee security""; ""Summary""; ""Further information""; ""4 Pain, stress and humane end points""; ""What is stress?""; ""Assessment of pain and distress""; ""Quantification of pain and distress""; ""Defining the humane end point""; ""Development of distress scoring systems""; ""Further information""""5 Humane methods of killing""""Introduction""; ""Preparation for humane killing""; ""Schedule 1 methods""; ""Other methods""; ""Confirmation of death and disposal of carcases""; ""Choice of methods""; ""Further information""; ""6 Introduction to laboratory animal husbandry""; ""Selection of animals""; ""Health monitoring""; ""Supply of laboratory animals""; ""Transport of laboratory animals""; ""Handling laboratory animals""; ""Introduction to laboratory animal husbandry""; ""Further information""; ""Websites""; ""7 Anaesthesia of laboratory animals""; ""Choosing an anaesthetic""""Pre-operative care""""Pre-anaesthetic drugs""; ""General anaesthesia: inhalation or injection?""; ""General anaesthetic drugs""; ""Anaesthetic management""; ""Muscle relaxation in anaesthesia""; ""A guide to anaesthetics/analgesics and Related drugs""; ""Further information""; ""8 Management of pain, suffering, distress and lasting harm""; ""Animal care: management of distress""; ""Management of pain""; ""Post-operative care""; ""Additional considerations in pain management""; ""Further information""; ""9 Conduct of minor procedures""; ""Administration of substances""""Legal categories and restrictions governing the use of drugs used in experimental animals""""Removal of blood""; ""Record keeping""; ""Indwelling cannulae, arterial loops and fistulae""; ""Miscellaneous methods of administration and sampling""; ""Polyclonal antibody production in Laboratory Animals""; ""Animal models""; ""Equipment for carrying out minor procedures""; ""Further information""; ""10 Introduction to surgery and suturing""; ""Introduction to surgical biology""; ""Principles of surgery""; ""Surgical techniques""; ""Surgical equipment""""Perioperative antibiosis and post-operative Wound infections""This third edition of the bestseller Handbook of Laboratory Animal Management & Welfare has been fully revised and updated making it an essential handbook for all those working with animals under the Animals (Scientific Procedures) Act, 1986. Designed to be a practical reference book, it covers every area of animal care and aims to improve animal welfare through best practice and refinement of techniques. It covers principles applicable to all species, including training of licensees, the regulatory framework, euthanasia, management of pain and stress, anaesthesia and surgery, and also includeLaboratory animalsHandbooks, manuals, etcAnimal welfareHandbooks, manuals, etcAnimal experimentationHandbooks, manuals, etcLaboratory animalsAnimal welfareAnimal experimentation636.0885Wolfensohn Sarah983707Lloyd MaggieMiAaPQMiAaPQMiAaPQBOOK996197695603316Handbook of laboratory animal management and welfare2860596UNISA