01264nam--2200385---450-99000315247020331620090608173853.0978-88-217-2860-0000315247USA01000315247(ALEPH)000315247USA0100031524720080929d2008----km-y0itay50------baitaIT||||||||001yy<<Il>> danno ambientale e la bonifica dei siti inquinatila nuova disciplina dopo il D.Lgs. 152/2006 e la sua riformaLuca Prati[Milanofiori, Assago]IPSOA[Roma]Indicitaliacopyr. 2008XI, 299 p.24 cmTesto unico ambientale32001Testo unico ambientale2001001-------2001Danni [da] InquinamentoResponsabilitàBNCF346.45032PRATI,Luca292676ITsalbcISBD990003152470203316XXIV.3.P 111 (IG XVI 682)60879 G.IG XVI00167089BKGIUFIORELLA9020080929USA011350RSIAV39020090608USA011738Danno ambientale e la bonifica dei siti inquinati810253UNISA03405nam 22004813a 450 991083181700332120231108184549.00-8248-9213-5(CKB)5690000000045530(BIP)081634644(ScCtBLL)86754ca5-614f-4885-a311-6105097bb228(EXLCZ)99569000000004553020231108i20222022 uu enguru||||||||||txtrdacontentcrdamediacrrdacarrierAcross Species and Cultures (PDF) : Whales, Humans, and Pacific Worlds /Ryan Tucker Jones, Angela Wanhalla[s.l.] :University of Hawaii Press,2022.1 online resource (336 p.) illAsia Pacific Flows0-8248-8898-7 More than any other locale, the Pacific Ocean has been the meeting place between humans and whales. From Indigenous Pacific peoples who built lives and cosmologies around whales, to Euro-American whalers who descended upon the Pacific during the nineteenth century, and to the new forms of human-cetacean partnerships that have emerged from the late twentieth century, the relationship between these two species has been central to the ocean's history. Across Species and Cultures: Whales, Humans, and Pacific Worlds offers for the first time a critical, wide-ranging geographical and temporal look at the varieties of whale histories in the Pacific. The essay contributors, hailing from around the Pacific, present a wealth of fascinating stories while breaking new methodological ground in environmental history, women's history, animal studies, and Indigenous ontologies. In the process they reveal previously hidden aspects of the story of Pacific whaling, including the contributions of Indigenous people to capitalist whaling, the industry's exceptionally far-reaching spread, and its overlooked second life as a global, industrial slaughter in the twentieth century. While pointing to striking continuities in whaling histories around the Pacific, Across Species and Cultures also reveals deep tensions: between environmentalists and Indigenous peoples, between ideas and realities, and between the North and South Pacific. The book delves in unprecedented ways into the lives and histories of whales themselves. Despite the worst ravages of commercial and industrial whaling, whales survived two centuries of mass killing in the Pacific. Their perseverance continues to nourish many human communities around and in the Pacific Ocean where they are hunted as commodities, regarded as signs of wealth and power, act as providers and protectors, but are also ancestors, providing a bridge between human and nonhuman worlds.Asia Pacific FlowsHistory / OceaniabisacshSocial Science / AnthropologybisacshNature / Environmental Conservation & ProtectionbisacshNatureAquacultureTechnology & engineeringHistory / OceaniaSocial Science / AnthropologyNature / Environmental Conservation & ProtectionNature639.28091823Jones Ryan TuckerWanhalla AngelaScCtBLLScCtBLLBOOK9910831817003321UNINA04719nam 2201249z- 450 991055789890332120210501(CKB)5400000000046291(oapen)https://directory.doabooks.org/handle/20.500.12854/69010(oapen)doab69010(EXLCZ)99540000000004629120202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierFibroblast Growth Factor Receptor (FGFR) Signaling Pathway in TumorBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (276 p.)3-03936-784-6 3-03936-785-4 Fibroblast growth factor (FGF) signal transmission has an essential function in embryonic development and tissue repair, and is dysregulated in the vast majority of malignancies studied. The FGF signaling in the tumor cells is usually increased by autocrine and paracrine mechanisms and gives them a high growth potential, resistance to apoptosis, neoangiogenesis and metastasis, all essential parameters relevant for tumor progression. This makes FGFs, and their tyrosine kinase receptors FGFRs, valuable targets for therapeutic interventions. This book is a collection of 15 recent articles-both original work and reviews-that summarize the current research state effectively. The content covers FGF signaling aspects in gastric, skin, liver, esophageal cancer, melanoma, mesothelioma and glioblastoma, including one article that addresses the role of FGF in the tumor-microenvironment cross-talk. Several reports describe the development of compounds targeting FGFRs, their structure and interaction with the receptor molecules, and their effectivity in preclinical and clinical testing. In summary, the papers demonstrate the complexity of the topic, with various FGF ligands and receptors involved and the need for further research. They also present results that fuel hope that targeting cancer with dysfunctional FGF signaling can become a realistic treatment option.Fibroblast Growth Factor Receptor Medicinebicsscadenocarcinoma of the esophagogastric junctionAKTanticancerastrocytomaautocrine signalingautophagybrain cancerbreast cancercancercancer signalingcancer-associated fibroblastscoreceptorERKERK1/2estrogenFGFFGF-mediated signalingFGF18FGF19FGF2FGF8FGFRFGFR1FGFR2FGFR2cFGFR4fibroblast growth factorfibroblast growth factor receptorsFRS2gastric cancergene regulationGPERHCCHEK293immunohistochemistryinfigratinib sensitivityinhibitorsJNK1keratinocytekinase inhibitorLY2874455malignant gliomamalignant pleural mesotheliomamelanomamembrane proteinsmonoclonal antibodyMTORn/anegative feedback loopneoadjuvant therapyneurite outgrowthNVP-BGJ398optogeneticsoverall survivalPC12phosphorylationprognosisreceptor cross-talkreceptor kinaseresistancereviewsarcomaseborrheic keratosisserinesignalingskinsmall moleculeSprouty proteinssquamous and basal cell carcinomastructuretargeted therapytumor promotertumor suppressorMedicineHolzmann Klausedt1295512Marian BrigitteedtHolzmann KlausothMarian BrigitteothBOOK9910557898903321Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor3023558UNINA