01077nam 2200361 450 99000074301020331688-204-8564-80074301USA010074301(ALEPH)000074301USA01007430120011114d1994----km-y0itay0103----baitaIT||||||||001yy<<Il>> sistema-qualità per la produzione del softwareGiorgio IrtinoMilanoF. Angelic1994108 p23 cmCollana di informatica EDP642001Collana di informatica EDP64Aziende di softwareGestione005.1068IRTINO,Giorgio411177ITsalbcISBD990000743010203316005.1068 IRT3190 EC005.1068BKECOPATTY9020011114USA01160120020403USA011722PATRY9020040406USA011651Sistema-qualità per la produzione del software963573UNISA03345nam 2200697 a 450 991080868930332120241030155820.0978661362221197812805923861280592389978111830983411183098399781118309872111830987197811183098651118309863(CKB)2670000000203832(EBL)832598(OCoLC)793995928(SSID)ssj0000632078(PQKBManifestationID)11386458(PQKBTitleCode)TC0000632078(PQKBWorkID)10599598(PQKB)11718969(MiAaPQ)EBC832598(Au-PeEL)EBL832598(CaPaEBR)ebr10643080(CaONFJC)MIL362221(PPN)178931357(Perlego)1002972(EXLCZ)99267000000020383220111116d2012 uy 0engurcn|||||||||txtccrApplications of transition metal catalysis in drug discovery and development an industrial perspective /edited by Matthew L. Crawley, Barry M. Trost1st ed.Hoboken, N.J. John Wiley & Sonsc20121 online resource (376 p.)Description based upon print version of record.9780470631324 0470631325 Includes bibliographical references and index.Transition metal catalysis in the pharmaceutical industry / Carl A. Busacca ... [et al.] -- Selected applications of transition metal-catalyzed carbon-carbon cross-coupling reactions in the pharmaceutical industry / Hong C. Shen -- Selected applications of Pd and Cu-catalyzed carbon-heteroatom cross-coupling reactions in the pharmaceutical industry / Jingjun Yin -- Asymmetric cross-coupling reactions / William A. Szabo and Vince Yeh -- Metathesis / Oliver Thiel -- Transition metal-catalyzed synthesis of five and six membered heterocycles / Cheol K. Chung and Matthew L. Crawley -- Oxidative catalysis / Lamont Terrell -- Industrial asymmetric hydrogenation / Hans-Ulrich Blaser.This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discoveryDrug developmentTransition metal catalystsDrug development.Transition metal catalysts.615.1/9Crawley Matthew L1718969Trost Barry M91554MiAaPQMiAaPQMiAaPQBOOK9910808689303321Applications of transition metal catalysis in drug discovery and development4116360UNINA