04770nam 2200625 450 991079781940332120230120002234.00-12-800030-90-12-800797-4(CKB)3710000000527127(EBL)4179308(MiAaPQ)EBC4179308(Au-PeEL)EBL4179308(CaPaEBR)ebr11123674(CaONFJC)MIL875733(OCoLC)930489358(EXLCZ)99371000000052712720160102d2015 uy| 0engur|n|---|||||rdacontentrdamediardacarrierPlant cyclotides /volume editor, David J. Craik, Institute for Molecular Bioscience, the University of Queensland, Brisbane, QLD, AustraliaFirst edition.Amsterdam :Elsevier,2015.1 online resource (404 p.)Advances in botanical research,0065-2296 ;volume seventy-sixDescription based upon print version of record.Includes bibliographical references and indexes.Front Cover; ADVANCES IN BOTANICAL RESEARCH; Plant Cyclotides; Copyright; Contents; CONTRIBUTORS; PREFACE; One - Overview on the Discovery and Applications of Cyclotides; 1. INTRODUCTION; ACKNOWLEDGMENTS; REFERENCES; Two - Cyclotides in the Violaceae; 1. THE DISCOVERY OF CYCLOTIDES IN VIOLACEAE; 2. UNLOCKING THE CYCLOTIDE LIBRARY; 3. THE VIOLACEAE; 4. VIOLACEAE-THE PHARMACOPOEIA; 5. GROWING NEEDS AND SOURCES OF CYCLOTIDES; 6. COMPLETING THE CIRCLE; ACKNOWLEDGMENTS; REFERENCES; Three - Cyclotides in the Rubiaceae; 1. INTRODUCTION; 2. DISCOVERY OF CYCLOTIDES2.1 Cyclotide Analytical Screening Workflow2.2 Cyclotides Sequence Analysis Using Transcriptomics and Peptidomics; 3. DISTRIBUTION OF CYCLOTIDES IN RUBIACEAE; 3.1 Rubiaceae-An Overview; 3.2 Morphology and Taxonomy of Rubiaceae; 3.3 Distribution of Cyclotides within Rubiaceae; 3.4 Cyclotide Precursors of Rubiaceae Plants; 3.5 Cyclotide Sequence Variations within Rubiaceae; 3.6 Distribution of Cyclotides in Other Gentianales; 4. EVOLUTION OF CYCLOTIDES; 5. BIOACTIVITIES OF RUBIACEAE CYCLOTIDES; 6. CONCLUSION AND OUTLOOK; ACKNOWLEDGMENTS; REFERENCES; Four - Cyclotides from Chinese Plants1. Introduction2. Chemical Detection Method for Cyclotides; 3. Distribution and Chemotaxonomy of Cyclotides in Chinese Plants; 4. Extraction, Isolation and Structural Elucidation of Cyclotides in Chinese Plants; 4.1 Extraction and Isolation of Cyclotides in Chinese Plants; 4.2 Tandem MS Sequencing of Cyclotides in Chinese Plants; 4.3 NMR Characterization of Cyclotides in Chinese Plants; 5. Biological Activity of Cyclotides in Chinese Plants; Acknowledgments; References; Five - Primary Structural Analysis of Cyclotides; 1. CYCLOTIDE DISCOVERY-UNTANGLING THE CYSTINE KNOT2. TOOLS FOR PEPTIDE SEQUENCE ASSIGNMENT2.1 Gene Sequencing; 2.2 Genome Mining; 2.3 Next-Generation Sequencing; 2.4 Peptide Extraction and Purification; 2.5 Acid Hydrolysis and Amino Acid Analysis; 2.6 Edman Degradation; 2.7 Chemical and Enzymatic Digestion; 3. MASS SPECTROMETRY; 3.1 Ionization; 3.1.1 Electrospray Ionization; 3.1.2 Nanoelectrospray Ionization; 3.1.3 Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry; 3.2 Mass Analyzers; 3.2.1 Quadrupole Mass Analyzers; 3.2.2 TOF Mass Analyzers; 3.3 Peptide Sequencing; 4. APPLICATION OF MASS SPECTROMETRY TO CYCLOTIDE SEQUENCING4.1 MS Analysis of Cyclotides4.2 Tandem Mass Spectrometric (MS/MS) Analysis of Cyclotides; 4.3 Application of "Omics" Technologies to Cyclotide Sequencing; 5. CHALLENGES AND COMPLEXITIES; 5.1 Co-eluting, Isobaric Peptides; 5.2 N/D Isoforms; 5.3 Unknown Genomes/Incomplete DBs; 6. FUTURE PROSPECTS; 6.1 Transcriptomics and Bioinformatics; 6.2 Automation and Robotics; 6.3 Advances in MS Hardware; 6.4 Advances in MS Software; 7. CONCLUDING REMARKS; REFERENCES; Six - Structural Studies of Cyclotides; 1. THE CYCLIC CYSTINE KNOT; 2. STRUCTURAL FEATURES OF CYCLOTIDES; 2.1 Structural Studies2.2 Möbius, Bracelets, and Trypsin InhibitorsAdvances in botanical research ;v. 76.BotanyResearchPlant molecular biologyPlant proteomicsPeptidesBotanical chemistryBotanyResearch.Plant molecular biology.Plant proteomics.Peptides.Botanical chemistry.Craik DavidMiAaPQMiAaPQMiAaPQBOOK9910797819403321Plant cyclotides3691044UNINA01843nam0 22003011i 450 UON0042468620231205104842.120130516d1991 |0itac50 baitaIT|||| 1||||ˆL'‰Assenza e la vocescena e intreccio della scrittura in Christina Rossetti, May Sinclair e Christine Brook-RoseMaria Del Sapio GraberoNapoliLiguori1991341 p.22 cm. 5 copie.TeatroArtistiUONC038901FIITNapoliUONL000012792.02809Teatro. Recitazione ed esecuzione. Storia, geografia, persone21GARBEROMaria Del SapioUONV216108711016LiguoriUONV246456650ITSOL20260116RICAUON00424686SIBA - SISTEMA BIBLIOTECARIO DI ATENEO E ARCHIVIO STORICOSI Angl VI C 0909 SI LO 47666 5 0909 BuonoSIBA - SISTEMA BIBLIOTECARIO DI ATENEO E ARCHIVIO STORICOSI Angl VI C 0910 SI LO 47665 5 0910 BuonoSIBA - SISTEMA BIBLIOTECARIO DI ATENEO E ARCHIVIO STORICOSI Angl VI C 0911 SI LO 47664 5 0911 BuonoSIBA - SISTEMA BIBLIOTECARIO DI ATENEO E ARCHIVIO STORICOSI Angl VI C 0912 SI LO 47663 5 0912 BuonoSIBA - SISTEMA BIBLIOTECARIO DI ATENEO E ARCHIVIO STORICOSI Angl VI C 0913 SI LO 47667/1 5 0913 BuonoAssenza e la voce1333458UNIOR