00905nam0-2200277---450-99000913184040332120100107111045.0000913184FED01000913184(Aleph)000913184FED0100091318420100107d1919----km-y0itay50------baitaIT--------001yy<<La >>protezione interalleata degli invalidi e dei mutilati di guerra e la legislazione internazionale del lavoroSalvatore GalganoRomaNuova Antologia191911 p.18 cmGalgano,Salvatore225063ITUNINARICAUNIMARCBK990009131840403321DP XII-3/1026151DECDECProtezione interalleata degli invalidi e dei mutilati di guerra e la legislazione internazionale del lavoro782736UNINA00870nam0-2200313---450 991058839350332120220909094524.0000884386FED01000884386(Aleph)000884386FED0100088438620090421d1955----km-y0itay50------bafreFRy-------001yy<<L'>>essence du prophétismepar André NeherParisPresses universitaires de France1955359 p.20 cmÉpiméthéeessais philosophiquesFilosofiaStoria della filosofiaNeher,Andre159086ITUNINARICAUNIMARCBK9910588393503321190 EPIM 010bibl.27809FLFBCFLFBCEssence du prophétisme26865UNINA01104nam2 22002771i 450 UON0042219420231205104830.30220130410d1956 |0itac50 bafreFR|||| 1||||ˆ1.: ‰1893-1906de Paul LéautaudParisMercure de France1956364 p.21 cm.001UON004221932001 Journal littérairede Paul Léautaud210 ParisMercure de France1956-1964215 16 vol.21 cm.1GIORNALISMO LETTERARIOUONC042050FIFRParisUONL002984070.92Giornalismo e giornali. Persone21LEAUTAUDPaulUONV215119197395Mercure de FranceUONV255879650ITSOL20240220RICASIBA - SISTEMA BIBLIOTECARIO DI ATENEOUONSIUON00422194SIBA - SISTEMA BIBLIOTECARIO DI ATENEOSI Francese VI A LEA 01 SI SFR1099 5 01 Buono1893-19061184641UNIOR05994nam 22007215 450 991043782880332120250530163239.01-283-69781-54-431-54038-510.1007/978-4-431-54038-0(CKB)2670000000280039(EBL)1030654(OCoLC)813296754(SSID)ssj0000766956(PQKBManifestationID)11513376(PQKBTitleCode)TC0000766956(PQKBWorkID)10739156(PQKB)11372762(DE-He213)978-4-431-54038-0(MiAaPQ)EBC1030654(PPN)168332272(EXLCZ)99267000000028003920121009d2013 u| 0engur|n|---|||||txtccrChembiomolecular Science At the Frontier of Chemistry and Biology /edited by Masakatsu Shibasaki, Masamitsu Iino, Hiroyuki Osada1st ed. 2013.Tokyo :Springer Japan :Imprint: Springer,2013.1 online resource (319 p.)Description based upon print version of record.4-431-54037-7 Includes bibliographical references and index.Part 1 Chembiomolecular Chemistry. Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer -- Practical Synthesis of Tamiflu and Beyond -- An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis -- Inhibitors of Fatty Acid Amide Hydrolase -- Small Molecule Tools for Cell Biology and Cell Therapy -- Toward the Discovery of Small Molecules Affecting RNA Function -- New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases -- The Deep Oceans as a Source for New Treatments for Cancer -- Search for New Medicinal Seeds from Marine Organisms -- Identification of Protein–Small Molecule Interactions by Chemical Array -- Part 2 Chembiomolecular Biology. Small Molecule-Induced Proximity -- High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing -- Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans -- Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis -- Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal -- Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis -- Establishment of a Novel System for Studying the Syk Function in B Cells -- Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures -- Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases -- Antiviral MicroRNA. - Synaptic Function Monitored Using Chemobiomolecular Indicators -- Part 3 Chembiomolecular Medicinal Chemistry. Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate -- Hunting the Targets of Natural Product-Inspired Compounds -- Chemical Approaches for Understanding and Controlling Infectious Diseases -- Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-gAgonists -- Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase -- Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases -- Enzymes as Chemotherapeutic Agents -- Mechanism of Action of New Antiinfectious Agents from Microorganisms -- Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease -- Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications.At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.BiochemistryCytologyMedicineResearchBiologyResearchBiochemistryCell BiologyBiomedical ResearchBiochemistry.Cytology.MedicineResearch.BiologyResearch.Biochemistry.Cell Biology.Biomedical Research.572Shibasaki Masakatsu66604Iino Masamitsu1760120Osada Hiroyuki1760121Uehara Memorial Foundation SymposiumMiAaPQMiAaPQMiAaPQBOOK9910437828803321Chembiomolecular science4198941UNINA