01596nam0 22003251i 450 UON0006830820231205102339.93839-275-1001-720020107d1989 |0itac50 baengDE|||| |||||African and Western legal systems in contact[T. Akinola Aguda, Abdur Rahman I Doi, B. A. Rwezaura]BayreuthBreitingerc198989 p.21 cmIl meccanismo della giustizia, l'addestramento e la nomina dei giudici in Nigeria - L'impatto dei concetti della Legge inglese sull'amministrazione della Legge islamica in Nigeria - Il mutamento di ruolo della famiglia allargata nel provvedimento del sostegno economico ad un individuo in Africa001UON000655842001 Bayreuth African Studies SeriesEditor Eckhard Breitinger11DirittoAfricaRelazioni con l'OccidenteUONC018376FIBayreuthUONL001840344.6LEGISLAZIONE SOCIALE - Africa21AKINOLA AGUDAT.UONV042258657237DOIAbdur Rahman IUONV042259657238RWEZAURAB. A.UONV042260657188BreitingerUONV256695650ITSOL20250207RICASIBA - SISTEMA BIBLIOTECARIO DI ATENEOUONSIUON00068308SIBA - SISTEMA BIBLIOTECARIO DI ATENEOSI ST 261 SI AA 11846 5 261 African and Western legal systems in contact1169996UNIOR03819nam 22006735 450 991029858460332120200705172916.03-030-00853-310.1007/978-3-030-00853-6(CKB)4100000006999362(MiAaPQ)EBC5534440(DE-He213)978-3-030-00853-6(PPN)231462220(EXLCZ)99410000000699936220181001d2018 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierGold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins /by Raphael Enoque Ferraz de Paiva1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (184 pages)Springer Theses, Recognizing Outstanding Ph.D. Research,2190-50533-030-00852-5 Au(I)-phosphine series design -- Probing the Protein: Ion Mobility Spectrometry -- Probing Gold: X-ray Absorption Spectroscopy -- Probing Cells: Cytotoxicity Evaluation -- Au(III) series with k2C,N and k2N,N' ligands -- "Dual Probe" X-ray Absorption Spectroscopy.This book examines Au (I, III) complexes that selectively attack and inhibit zinc finger proteins (ZnFs) for potential therapeutic use. The author explores gold(I)-phosphine, gold(III) complexes with N^N and C^N donors as inhibitors of the HIV-1 nucleocapsid protein (NCp7), in comparison to the human transcription factor Sp1. To determine the coordination sphere of the gold adducts formed by interaction with ZnFs, two innovative approaches are used, based on Travelling-Wave Ion Mobility coupled with Mass Spectrometry (TWIM-MS), and X-ray Absorption Spectroscopy. Both approaches are proven to yield valuable structural information regarding the coordination sphere of gold in the adducts. In addition, the organometallic compound [Au (bnpy)Cl2] is evaluated. The system is shown to be capable of inhibiting ZnFs by means of C–S coupling.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053Chemistry, InorganicOrganometallic chemistryProteinsMass spectrometryBioorganic chemistryImmunologyInorganic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C16008Organometallic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19020Protein-Ligand Interactionshttps://scigraph.springernature.com/ontologies/product-market-codes/L14060Mass Spectrometryhttps://scigraph.springernature.com/ontologies/product-market-codes/C11010Bioorganic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19010Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Chemistry, Inorganic.Organometallic chemistry.Proteins.Mass spectrometry.Bioorganic chemistry.Immunology.Inorganic Chemistry.Organometallic Chemistry.Protein-Ligand Interactions.Mass Spectrometry.Bioorganic Chemistry.Immunology.571.845Ferraz de Paiva Raphael Enoqueauthttp://id.loc.gov/vocabulary/relators/aut1059031BOOK9910298584603321Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins2503745UNINA