01916nam 2200409z- 450 991111552900332120210211(CKB)4100000002484695(oapen)https://directory.doabooks.org/handle/20.500.12854/42712(oapen)doab42712(EXLCZ)99410000000248469520202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierCardiac Remodeling: New Insights in Physiological and Pathological AdaptationsFrontiers Media SA20171 online resource (117 p.)Frontiers Research Topics2-88945-331-6 The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.Cardiac RemodelingPhysiologybicsscCardiac RemodelingFibrosisHeart FailureInflammationPhysiologyPhysiologyLeonardo Roeverauth2006531Antonio C. Palandri ChagasauthBOOK9911115529003321Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations4792929UNINA