04304nam 2201237z- 450 991105322100332120230911(CKB)5690000000228572(oapen)doab113994(EXLCZ)99569000000022857220230920c2023uuuu -u- -engurmn|---annantxtrdacontentcrdamediacrrdacarrierMolecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons FunctionsMDPI - Multidisciplinary Digital Publishing Institute20231 online resource (290 p.)3-0365-8714-4 The human brain has hundreds of billions of neurons, and at least 7 million dendrites have been hypothesized to exist for each neuron, with over 100 trillion neuron-neuron, neuron-muscle, and neuron-endocrine cell synapses [1,2]. Our body continually receives stimuli from the outer environment, and our brain's ability to respond to these stimuli is ensured through synaptic processes, motivating the foundations of this Special Issue.This reprint aims to underline the role of synaptic plasticity phenomena in our body and clarify the mechanism operated by neurons to guarantee these phenomena. The collection in the Issue comprises 14 papers, including 8 reviews and 6 original works, one of which is a protocol for differentiating neurons from human stem cells, and 5 are preclinical works.Molecular Mechanisms of Synaptic PlasticityBiology, life sciencesbicsscResearch & information: generalbicsscAlzheimer's disease (AD)AM251amygdalaautophagybrain connectivitybrain developmentbrain disordersbrain networkscaspase-3Circular Hole Boardcognitioncomputational neuroscienceconnectivityD2 receptorsdendritic spinesdopaminedopamine transporterdopamine volume transmissiondorsal striatumdystoniaendocannabinoid systemErbB receptorsGABAgliaglucocorticoidsglutamateGlutamategut-brain axishigh contrasthippocampushuman neuronsimmunoproteasomeinduced neural stem cellsinflammationinhibitionlearning and memorylong-term depressionlong-term potentiationlong-term potentiation (LTP)LTDLTPmicemidbrain dopamine neuronsmTORmultiple sclerosisn/aneuregulinsneuro-inflammationneurodevelopmental diseasesneuronal cytoarchitectureneuroplasticityneurovascular unitNMDA receptorsnoradrenalineParkinson's diseasePINK1proteasomeregulatory T cellsresting state functional MRI (rs-fMRI)reticular formationSchaffer collateral-CA1 synapsesschizophreniaserotonin (5-HT)SNARE proteinsspatial learningstriatumsynapsesynapsessynaptic plasticitysynaptic scalingsynaptic vesiclessystems biologyT-cellstransmission electron microscopytripartite synapsetyrosine hydroxylaseBiology, life sciencesResearch & information: generalBOOK9911053221003321Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions4525358UNINA