01493nam 22004093 450 991102866510332120250927060322.03-031-89669-6(CKB)41002186600041(MiAaPQ)EBC32317251(Au-PeEL)EBL32317251(EXLCZ)994100218660004120250927d2025 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierGroup Sequential and Confirmatory Adaptive Designs in Clinical Trials2nd ed.Cham :Springer,2025.©2025.1 online resource (646 pages)Springer Series in Pharmaceutical Statistics Series3-031-89668-8 This book provides an up-to-date review of the general principles and techniques of confirmatory adaptive designs, a generalization of group sequential designs.With these designs, interim analyses are performed in order to stop a trial prematurely under control of the Type I error rate.Springer Series in Pharmaceutical Statistics Series615.50724Wassmer Gernot755933Brannath Werner755934MiAaPQMiAaPQMiAaPQBOOK9911028665103321Group sequential and confirmatory adaptive designs in clinical trials1523374UNINA