02434nam 22006254a 450 991102037200332120200520144314.09786611203863978128120386112812038669780470191750047019175997804701917430470191740(CKB)1000000000377295(EBL)331570(OCoLC)476131032(SSID)ssj0000137134(PQKBManifestationID)11150378(PQKBTitleCode)TC0000137134(PQKBWorkID)10087973(PQKB)11219748(MiAaPQ)EBC331570(Perlego)2757508(EXLCZ)99100000000037729520070425g20089999 uy 0engur|n|---|||||txtccrDesign and analysis of experiments /Klaus Hinkelmann, Oscar Kempthorne2nd ed.Hoboken, N.J. Wiley-Intersciencec2008-1 online resource (667 p.)Wiley series in probability and statisticsKempthorne's name appears first on the earlier ed.9780471727569 0471727563 Includes bibliographical references and indexes.v. 1. Introduction to experimental designThis user-friendly new edition reflects a modern and accessible approach to experimental design and analysis Design and Analysis of Experiments, Volume 1, Second Edition provides a general introduction to the philosophy, theory, and practice of designing scientific comparative experiments and also details the intricacies that are often encountered throughout the design and analysis processes. With the addition of extensive numerical examples and expanded treatment of key concepts, this book further addresses the needs of practitioners and successfully provides a solid understanding of the reWiley series in probability and statistics.Experimental designExperimental design.519.5/7Hinkelmann Klaus1932-898119Kempthorne Oscar14458MiAaPQMiAaPQMiAaPQBOOK9911020372003321Design and analysis of experiments4418515UNINA03676nam 2200973z- 450 991055710240332120210501(CKB)5400000000041023(oapen)https://directory.doabooks.org/handle/20.500.12854/69447(oapen)doab69447(EXLCZ)99540000000004102320202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Advances and Applications of OptogeneticsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (164 p.)3-03943-673-2 3-03943-674-0 This book provides an update for the rapidly developing technology known as "optogenetics", which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research.Biology, life sciencesbicsscResearch and information: generalbicsscall-optical electrophysiologyAsLOV2azobenzeneBLUFcalciumcalcium sensorchannelrhodopsinchannelrhodopsin-2channelrhodopsinsChlamydomonas reinhardtiiCTMD method, residual hydrophobic mismatchDC gateelectrophysiologyenergy of membrane deformationflash photolysishippocampal neuronshybrid QM/MM simulationintracellular traffickingion channelion channelsLEXYlight stimulationLINuSLOV domainsmembrane currentmembrane potentialmembrane-protein interactionmicrobial rhodopsinmicrobial rhodopsinsMIPmodular domainmolecular dynamics simulationsneuroscienceneurotransmittersoptogenetic toolsoptogeneticsOptogeneticsp53photocontrolphotoreceptorphotoswitchphotoswitchingPMIprotein-protein interactionresonance Ramansignalingsodiumtwo-photonvoltage sensorBiology, life sciencesResearch and information: generalGovorunova Elena Gedt1320353Sineshchekov Oleg AedtGovorunova Elena GothSineshchekov Oleg AothBOOK9910557102403321The Advances and Applications of Optogenetics3034178UNINA