04898nam 2200673Ia 450 991102024040332120200520144314.09786612372247978128237224512823722469783527622009352762200497835276220163527622012(CKB)1000000000687520(EBL)482242(OCoLC)609855563(SSID)ssj0000307249(PQKBManifestationID)11247313(PQKBTitleCode)TC0000307249(PQKBWorkID)10243602(PQKB)10375718(MiAaPQ)EBC482242(PPN)194582779(Perlego)2773818(EXLCZ)99100000000068752020071029d2008 uy 0engur|n|---|||||txtccrPseudomonas model organism, pathogen, cell factory /edited by Bernd H.A. RehmWeinheim ;Chichester Wiley-VCH20081 online resource (426 p.)Description based upon print version of record.9783527319145 352731914X Includes bibliographical references and index.Pseudomonas; Contents; Preface; List of Contributors; 1 Comparative Genomics of Pseudomonas; 1.1 Introduction; 1.1.1 Other Species of Pseudomonas; 1.1.2 Obtaining Sequence Data on Pseudomonas; 1.2 Pan/Core Genome of Pseudomonas; 1.3 Phylogeny of Pseudomonas; 1.4 Blast Atlas of Pseudomonas Genomes; 1.4.1 Region 5 243 000-5 361 000; 1.4.2 Region 713 000-785 000; 1.5 Functional Categories; 1.6 Codon Usage and Expression; 1.7 Future Outlook; References; 2 Clinical Relevance of Pseudomonas aeruginosa: A Master of Adaptation and Survival Strategies; 2.1 Introduction; 2.2 CF2.3 Survival of P. aeruginosa by Adaptation to the Inflammatory Defense System2.4 Conductive and the Respiratory Zones of the Lungs; 2.5 Survival of P. aeruginosa by Adaptation to the Respiratory Zone of the Lungs; 2.6 Survival of P. aeruginosa by Adaptation to the Conductive Zone of the Lungs; 2.7 Survival of P. aeruginosa by Adaptation to the Antibiotic Therapy; 2.8 Evolutionary Implications of the Adaptability of P. aeruginosa; References; 3 Adherence of Pseudomonas aeruginosa; 3.1 Introduction; 3.2 What is Adherence?; 3.3 Role of Adherence in Infection3.4 How is Bacterial Adherence Associated with Virulence?3.5 P. aeruginosa Adhesins; 3.6 Surface Receptor Requirements of the Pilus Adhesin; 3.7 How Does PilA Mediate Attachment to Human Mucosal Surfaces?; 3.8 X-ray Crystallographic Structural Studies of the Pilin Structural Protein; 3.9 Structure of the Pilus Fiber; 3.10 Structure of the Receptor-Binding Domain and Location on the Pilus; 3.11 Structural Nature of the Receptor-Binding Domain; 3.12 Twitching Motility; 3.13 How Does the Pilus Attach to a Solid Surface?; 3.14 The Monkey-Bar Swing Paradox3.15 Molecular Basis for Receptor-binding Domain Interaction with Steel Surfaces3.16 Pili as Nanowires for Redox Reactions; 3.17 What is the Most Important Role of Adherence to P. aeruginosa; References; 4 Flagella and Pili of Pseudomonas aeruginosa; 4.1 Introduction; 4.2 Flagellum of P. aeruginosa; 4.2.1 Structure of the P. aeruginosa Flagellum; 4.2.2 Chromosomal Organization of the Flagellar Genes of P. aeruginosa; 4.2.3 Transcriptional Hierarchy of the Flagellar Genes; 4.2.4 Model Proposed for Flagellar Assembly in P. aeruginosa4.2.5 Environmental/Nonflagellar Regulators of Flagellar Expression4.2.6 Posttranslational Modification of Flagellin; 4.2.6.1 Flagellar Glycosylation Islands (GIs) in P. aeruginosa; 4.2.6.2 Polymorphism of the P. aeruginosa a-type GI; 4.2.7 Role of Flagella in Inflammation; 4.2.8 Role of Flagellum in Pathogenesis; 4.3 Pili of P. aeruginosa; 4.3.1 Structure of P. aeruginosa Pilus; 4.3.2 Pilus/Fimbrial Genes of P. aeruginosa; 4.3.3 Regulation of Pilus Assembly and Twitching Motility; 4.3.4 Assembly of Type IV Pili; 4.3.5 Pilin Classification; 4.3.5.1 Type IV a and b Pilins4.3.5.2 Group I-V PilinsConcise and up-to-date, this handy guide fills a gap in the literature by providing the essential knowledge for everyone with an interest in the topic. The result is a comprehensive overview of the most important model organism in applied microbiology that covers basic biology, pathology and biotechnological applications.PseudomonasPseudomonadaceaePseudomonas.Pseudomonadaceae.579.332Rehm Bernd1842381MiAaPQMiAaPQMiAaPQBOOK9911020240403321Pseudomonas4422454UNINA