05645nam 2200781Ia 450 991102005960332120200520144314.09786611284978978128128497612812849719780470276266047027626697804702762590470276258(CKB)1000000000400795(EBL)335762(OCoLC)214281848(SSID)ssj0000206423(PQKBManifestationID)11206821(PQKBTitleCode)TC0000206423(PQKBWorkID)10215079(PQKB)10169988(MiAaPQ)EBC335762(Perlego)2772260(EXLCZ)99100000000040079520071004d2008 uy 0engur|n|---|||||txtccrMultidimensional liquid chromatography theory and applications in industrial chemistry and the life sciences /edited by Steven A. Cohen, Mark R. SchureHoboken, N.J. Wiley-Intersciencec20081 online resource (490 p.)Description based upon print version of record.9780471738473 0471738476 Includes bibliographical references and index.MULTIDIMENSIONAL LIQUID CHROMATOGRAPHY; CONTENTS; Foreword; Preface; Contributors; 1 Introduction; 1.1 Previous Literature Which Covers MDLC; 1.2 How this Book is Organized; References; PART I THEORY; 2 Elements of the Theory of Multidimensional Liquid Chromatography; 2.1 Introduction; 2.2 Peak Capacity; 2.3 Resolution; 2.4 Orthogonality; 2.5 Two-Dimensional Theory of Peak Overlap; 2.6 Dimensionality, Peak Ordering, and Clustering; 2.7 Theory of Zone Sampling; 2.8 Dilution and Limit of Detection; 2.9 Chemometric Analysis; 2.10 Future Directions; References3 Peak Capacity in Two-Dimensional Liquid Chromatography3.1 Introduction; 3.2 Theory; 3.3 Procedures; 3.4 Results and Discussion; 3.5 Conclusions; Appendix 3A Generation of Random Correlated Coordinates; Appendix 3B Derivation of Limiting Correlation Coefficient r; References; 4 Decoding Complex 2D Separations; 4.1 Introduction; 4.2 Fundamentals: The Statistical Description of Complex Multicomponent Separations; 4.3 Decoding 1D and 2D Multicomponent Separations by Using the SMO Poisson Statistics; 4.4 Decoding Multicomponent Separations by the Autocovariance Function4.5 Application to 2D Separations4.5.1 Results from SMO Method; 4.5.2 Results from 2D Autocovariance Function Method; 4.6 Concluding Remarks; Acknowledgments; References; PART II COLUMNS, INSTRUMENTATION AND METHODS DEVELOPMENT; 5 Instrumentation for Comprehensive Multidimensional Liquid Chromatography; 5.1 Introduction; 5.2 Heart-Cutting Versus Comprehensive Mode; 5.3 Chromatographic Hardware; 5.3.1 Valves; 5.4 CE Interfaces; 5.4.1 Gated Interface for HPLC-CE; 5.4.2 Microfluidic Valves for On-Chip Multidimensional Analysis; 5.5 Columns and Combinations5.5.1 Column Systems, Dilution, and Splitting5.6 Detection; 5.7 Computer Hardware and Software; 5.7.1 Software Development; 5.7.2 Valve Sequencing; 5.7.3 Data Format and Storage; 5.8 Zone Visualization; 5.8.1 Contour Visualization; 5.8.2 2D Peak Presentation; 5.8.3 Zone Visualization in Specific Chemical (pI) Regions; 5.8.4 External Plotting Programs; 5.8.5 Difference Plots; 5.8.6 Multi-channel Data; 5.9 Data Analysis and Signal Processing; 5.10 Future Prospects; References; 6 Method Development in Comprehensive Multidimensional Liquid Chromatography; 6.1 Introduction; 6.2 Previous Work6.3 Column Variables6.4 Method Development; 6.4.1 The Cardinal Rules of 2DLC Method Development; 6.5 Planning the Experiment; 6.6 General Comments on Optimizing the 2DLC Experiment: Speed-Resolution Trade-off; Acknowledgment; References; 7 Monolithic Columns and Their 2D-HPLC Applications; 7.1 Introduction; 7.2 Monolithic Polymer Columns; 7.2.1 Structural Properties of Polymer Monoliths; 7.2.2 Chromatographic Properties of Polymer Monolithic Columns; 7.2.3 Two-Dimensional HPLC Using Polymer Monoliths; 7.3 Monolithic Silica Columns; 7.3.1 Preparation7.3.2 Structural Properties of Monolithic Silica ColumnsMultidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.BiochemistryChemical engineeringChemistry, TechnicalLiquid chromatographyBiochemistry.Chemical engineering.Chemistry, Technical.Liquid chromatography.543.84543/.8435.71bcl35.29bcl58.14bclVG 7500rvkCohen Steven A.1953-1838746Schure Mark R1838747MiAaPQMiAaPQMiAaPQBOOK9911020059603321Multidimensional liquid chromatography4417800UNINA01675nas 2200481-a 450 991089608800332120241221110108.0(DE-599)ZDB2707067-0(CKB)110985822459916(CONSER)--2015269517(MiFhGG)6RRR(EXLCZ)9911098582245991620001004a19999999 --- -spatxtrdacontentcrdamediacrrdacarrierHermēneusSoria [Spain] Facultad de Traducción e Interpretación de Soria, Universidad de Valladolid (Fatiso)1999-1 online resourceRefereed/Peer-reviewed"Revista de Traducción e Interpretación.""Revista de la Facultad de Traducción e Interpretación de Soria."Print version: Hermēneus (Soria, Spain) 1139-7489 (DLC) 2015269517 (OCoLC)45119111 Translating and interpretingLinguisticsLanguage and languagesLanguage and languagesfast(OCoLC)fst00992154Linguisticsfast(OCoLC)fst00999202Translating and interpretingfast(OCoLC)fst01154795Translating and interpreting.Linguistics.Language and languages.Language and languages.Linguistics.Translating and interpreting.17.45bclFacultad de Traducción e Interpretación de Soria.JOURNAL9910896088003321exl_impl conversionHermeneus892472UNINA