01030nam0-22003131i-450-990001223810403321000122381FED01000122381(Aleph)000122381FED0100012238120000920d1965----km-y0itay50------baengMathematical Analysis Differentiation and Integration.by Garamanovich I.G. Guter R. S. Lyusternik L.A. Raukhvarger I.L. Skanavi M.I. Yanpol'skii A.R.Oxford [etc.]Pergamon Press1965.International series of monographs on pure and applied mathematicsVolumi 81.̜Garamanovich,I.G.349422Guter,R.S.Lyusternik,L.A.Raukhvarger,L.I.Skanavi,M.I.ITUNINARICAUNIMARCBK990001223810403321C-37-(818400MA1MA1Mathematical Analysis Differentiation and Integration343403UNINAING0103891nam 2200673 a 450 991101981580332120200520144314.09786610855988978128085598612808559839780470511848047051184297804705118310470511834(CKB)1000000000356730(EBL)292589(SSID)ssj0000096623(PQKBManifestationID)11119996(PQKBTitleCode)TC0000096623(PQKBWorkID)10103902(PQKB)10678242(MiAaPQ)EBC292589(OCoLC)264621042(Perlego)2750284(EXLCZ)99100000000035673020071018d2007 uy 0engur|n|---|||||txtccrAcetaldehyde-related pathology bridging the trans-disciplinary divide /[chair, Peter Emery]8th ed.Chichester ;Hoboken, N.J. John Wiley20071 online resource (287 p.)Novartis Foundation symposium ;285Editors: Derek J. Chadwick and Jamie Goode.9780470057667 0470057661 Includes bibliographical references and indexes.Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide; Contents; Chair's introduction; Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes; Removal of acetaldehyde from the body; Acetaldehyde, polymorphisms and the cardiovascular system; Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models; Interrelationship between alcohol, smoking, acetaldehyde and cancer; Effects of acetaldehyde on human airway constriction and inflammationThe role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tractThe determination of acetaldehyde in exhaled breath; Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain; Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde; Alcoholic myopathy and acetaldehyde; Acetaldehyde adducts in circulation; General discussion; Pancreatic MAP kinase pathways and acetaldehyde; Acetaldehyde alters MAP kinase signalling and epigenetic histone modifications in hepatocytesEndogenous a-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damageMeasurement of acetaldehyde: what levels occur naturally and in response to alcohol?; Final discussion; Contributors Index; Subject indexPart of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer's. Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of Novartis Foundation symposium ;285.AcetaldehydeToxicologyAcetaldehydeToxicology.615.952Emery Peter1953-1842419Chadwick Derek91632Goode Jamie283336Novartis Foundation.MiAaPQMiAaPQMiAaPQBOOK9911019815803321Acetaldehyde-related pathology4422527UNINA