01215cam0 2200289 450 E60020007379120220303085856.0881822013620110412d1989 |||||ita|0103 baitaIT<<Il >>filosofo e la fedeSoliloqui - La vera religione - L'utilità del credere - La fede nelle cose che non si vedonoAurelio Agostinointroduzione traduzione prefazioni note e indici di Onorato GrassiMilanoRusconi1989336 p.22 cm<I >classici del pensieroSezione 1Filosofia classica e tardo antica001LAEC000295122001 I *classici del pensiero. Sezione 1, Filosofia classica e tardo anticaAugustinus, Aurelius <santo>AF00004539070152280Grassi, OnoratoA600200064902070ITUNISOB20220303RICAUNISOBUNISOB100|Coll|30|K72304E600200073791M 102 Monografia moderna SBNM100|Coll|30|K000037Si72304acquistopregresso2UNISOBUNISOB20110412081254.020220303085835.0AlfanoFilosofo e la fede475729UNISOB05321nam 2200661Ia 450 991101946120332120200520144314.09786612472329978128247232712824723219783527629251352762925497835276292683527629262(CKB)2550000000000263(EBL)481261(OCoLC)521036186(SSID)ssj0000354498(PQKBManifestationID)11275365(PQKBTitleCode)TC0000354498(PQKBWorkID)10314478(PQKB)10326037(MiAaPQ)EBC481261(Perlego)2764272(EXLCZ)99255000000000026320000327d2010 uy 0engur|n|---|||||txtccrModeling solvent environments applications to simulations of biomolecules /edited by Michael FeigWeinheim Wiley-VCH Verlag GmbHc20101 online resource (336 p.)Description based upon print version of record.9783527324217 3527324216 Includes bibliographical references and index.Modeling Solvent Environments: Applications to Simulations of Biomolecules; Contents; Preface; List of Contributors; 1: Biomolecular Solvation in Theory and Experiment; 1.1 Introduction; 1.2 Theoretical Views of Solvation; 1.2.1 Equilibrium Thermodynamics of Solvation; 1.2.2 Radial Distribution Functions; 1.2.3 Integral Equation Formalisms; 1.2.4 Kirkwood-Buff Theory; 1.2.5 Kinetic Effects of Solvation; 1.3 Computer Simulation Methods in the Study of Solvation; 1.3.1 Molecular Dynamics and Monte Carlo Simulations; 1.3.2 Water Models; 1.3.3 Solvent Structure and Dynamics from Simulations1.3.4 Free Energy Simulations1.4 Experimental Methods in the Study of Solvation; 1.4.1 X-Ray/Neutron Diffraction and Scattering; 1.4.2 Nuclear Magnetic Relaxation; 1.4.3 Optical Spectroscopy; 1.4.4 Dielectric Dispersion; 1.5 Hydration of Proteins; 1.5.1 Protein Folding and Peptide Conformations in Aqueous Solvent; 1.5.2 Molecular Properties of Water Near Protein Surfaces; 1.5.3 Water Molecules at Protein-Ligand and Protein-Protein Interfaces; 1.6 Hydration of Nucleic acids; 1.7 Non-Aqueous Solvation; 1.7.1 Alcohols; 1.7.2 Urea; 1.7.3 Glycerol; 1.8 Summary; References2: Model-Free "Solvent Modeling" in Chemistry and Biochemistry Based on the Statistical Mechanics of Liquids2.1 Introduction; 2.2 Outline of the RISM and 3D-RISM theories; 2.3 Partial Molar Volume of Proteins; 2.4 Detecting Water Molecules Trapped Inside Protein; 2.5 Selective Ion Binding by Protein; 2.6 Water Molecules Identified as a Substrate for Enzymatic Hydrolysis of Cellulose; 2.7 CO Escape Pathway in Myoglobin; 2.7.1 Effect of Protein Structure on the Distribution of Xe; 2.7.2 Partial Molar Volume Change Through the CO Escape Pathway of Myoglobin; 2.8 Perspective; References3: Developing Force Fields From the Microscopic Structure of Solutions: The Kirkwood-Buff Approach3.1 Introduction; 3.2 Biomolecular Force Fields; 3.3 Examples of Problems with Current Force Fields; 3.4 Kirkwood-Buff Theory; 3.5 Applications of Kirkwood-Buff Theory; 3.6 The General KBFF Approach; 3.7 Technical Aspects of the KBFF Approach; 3.8 Results for Urea and Water Binary Solutions; 3.9 Preferential Interactions of Urea; 3.10 Conclusions and Future Directions; Acknowledgments; References; 4: Osmolyte Influence on Protein Stability: Perspectives of Theory and Experiment; 4.1 Introduction4.2 Denaturing Osmolytes4.2.1 Does Urea Weaken Water Structure?; 4.2.2 Effect of Urea on Hydrophobic Interactions; 4.2.3 Direct Interaction of Urea with Proteins; 4.3 Protecting Osmolytes; 4.3.1 Do Protecting Osmolytes Increase Water Structure?; 4.3.2 Effect of Protecting Osmolytes on Hydrophobic Interactions; 4.4 Mixed Osmolytes; 4.5 Conclusions; Acknowledgments; References; 5: Modeling Aqueous Solvent Effects through Local Properties of Water; 5.1 The Role of Water and Cosolutes on Macromolecular Thermodynamics; 5.2 Forces Induced by Water in Aqueous Solutions5.2.1 Interactions in Water-Accessible Regions of ProteinsA comprehensive view of the current methods for modeling solvent environments with contributions from the leading researchers in the field. Throughout, the emphasis is placed on the application of such models in simulation studies of biological processes, although the coverage is sufficiently broad to extend to other systems as well. As such, this monograph treats a full range of topics, from statistical mechanics-based approaches to popular mean field formalisms, coarse-grained solvent models, more established explicit, fully atomic solvent models, and recent advances in applying ab initio meSolventsBiomoleculesSolvents.Biomolecules.541.3482011Feig Michael1838284MiAaPQMiAaPQMiAaPQBOOK9911019461203321Modeling solvent environments4417251UNINA00923nam 2200265zu 450 991094689290332120250116155133.0979-1-0915-9244-4(CKB)37202140800041(EXLCZ)993720214080004120250116|2023uuuu || |engur|||||||||||De la Bonne presse à Bayard 150 ans d'histoire d'un groupe de presse et d'édition catholique (1873-2023) /sous la direction de Delia Guijarro Arribas, Charles Mercier, Yann Raison du CleuziouLARHRA2023979-1-0915-9237-6 Catholic pressFranceHistoryCatholic pressHistory.Guijarro Arribas Delia1988-Mercier Charles1977-Raison du Cleuziou YannBOOK9910946892903321De la Bonne presse à Bayard4382001UNINA