01141nam2-22002891i-450 99000699901040332120210721112526.000069990120011120g19511972km-y0itay50------bafreFRTables generalespar Bernard Loth et Albert Michel avec le concours de plusieurs collaborateursParisLetouzey et Ane1951-197211 v.28 cm(1): Aaron-Hefele(2): Hefner-Innocent XII(3): Innocent XII-Jésuites(4): Jésuites-Juvernay(5): Kabale-Magie(6): Magie-Nicon(7): Nicon-Pénitence(8): Pénitence-Raison(9): Raison-Stolz(10): Stolz-Vaganay(11): Vaghachapat-Zwinglianisme0010006998942001Dictionnaire de theologie catholiqueLoth,Bernard206668Michel,Albert119675ITUNINARICAUNIMARCBK990006999010403321III AA 3 (1-11)8-100-DCEC230.03 DIZ.TEOL. TABLE (AARON-ESSENCE)Bibl. 29845FLFBCDCECFLFBCTables generales698828UNINA05451nam 2200697Ia 450 991101942360332120200520144314.09786610520602978128052060012805206049783527605590352760559297835276055453527605541(CKB)1000000000375902(EBL)481617(OCoLC)68965702(SSID)ssj0000141995(PQKBManifestationID)11147216(PQKBTitleCode)TC0000141995(PQKBWorkID)10091591(PQKB)10032194(MiAaPQ)EBC481617(Perlego)2758067(EXLCZ)99100000000037590220041129d2005 uy 0engur|n|---|||||txtccrDynamic studies in biology phototriggers, photoswitches and caged biomolecules /edited by Maurice Goeldner, Richard GivensWeinheim Wiley-VCHc20051 online resource (587 p.)Description based upon print version of record.9783527307838 3527307834 Includes bibliographical references and index.Dynamic Studies in Biology Phototriggers, Photoswitches and Caged Biomolecules; Contents; Foreword; Preface; List of Authors; 1 Photoremovable Protecting Groups Used for the Caging of Biomolecules; 1.1 2-Nitrobenzyl and 7-Nitroindoline Derivatives; 1.1.1 Introduction; 1.1.1.1 Preamble and Scope of the Review; 1.1.1.2 Historical Perspective; 1.1.2 Synthetic Considerations; 1.1.3 Survey of Individual Caged Compounds and Caging Groups; 1.1.3.1 2-Nitrobenzyl Cages; 1.1.3.1.1 Mechanistic Aspects of Photocleavage and By-Product Reactions of 2-Nitrobenzyl Cages1.1.3.1.2 Representative Survey of Nitrobenzyl-Caged Compounds1.1.3.2 7-Nitroindoline Cages; 1.1.3.2.1 Mechanistic and Structural Aspects of Photochemical Cleavage of 1-Acyl-7-nitroindolines; 1.1.3.2.2 Survey of 7-Nitroindoline Caged Compounds; 1.1.4 Conclusion; References; 1.2 Coumarin-4-ylmethyl Phototriggers; 1.2.1 Introduction; 1.2.2 Spectroscopic and Photochemical Properties; 1.2.2.1 Overview; 1.2.2.2 Phototriggers; 1.2.2.2.1 MCM Groups: 7-Alkoxy-Substituted Coumarins; 1.2.2.2.2 DMCM Groups: 6,7-Dialkoxy-Substituted Coumarins; 1.2.2.2.3 Bhc Groups: 6-Bromo-7-alkoxy-Substituted Coumarins1.2.2.2.4 DEACM Groups: 7-Dialkylamino-Substituted Coumarins1.2.2.3 Target Molecules; 1.2.2.3.1 Phosphates; 1.2.2.3.2 Carboxylates and Sulfates; 1.2.2.3.3 Amines; 1.2.2.3.4 Alcohols and Phenols; 1.2.2.3.5 Carbonyl Compounds; 1.2.3 Synthesis; 1.2.3.1 Synthesis of Precursor Molecules (Caging Agents); 1.2.3.1.1 Phosphates; 1.2.3.1.2 Carboxylates; 1.2.3.1.3 Amines; 1.2.3.1.4 Alcohols and Phenols; 1.2.4 Applications; 1.2.5 Conclusion and Perspective; References; 1.3 p-Hydroxyphenacyl: a Photoremovable Protecting Group for Caging Bioactive Substrates; 1.3.1 Introduction and History1.3.2 p-Hydroxyphenacyl1.3.2.1 General Physical and Spectroscopic Properties; 1.3.2.2 Synthesis of pHP-Caged Substrates; 1.3.3 Mechanistic Studies; 1.3.3.1 A Triplet "Photo-Favorskii" Rearrangement; 1.3.3.2 Role of the Triplet Phenol; 1.3.3.3 Correlation of the (3)pK(a) with the Quantum Efficiency; 1.3.4 Applications; 1.3.4.1 Neurotransmitter Release; 1.3.4.2 Peptide Release; 1.3.4.3 Nucleotide Release; 1.3.4.4 Enzyme Photoswitches; 1.3.5 Advantages and Limitations; References; 1.4 Caging of ATP and Glutamate: a Comparative Analysis; 1.4.1 Introduction1.4.2 General Properties for Caging Groups1.4.3 Caged-ATP; 1.4.3.1 Introduction; 1.4.3.2 Syntheses of the P(3)-caged ATP Derivatives; 1.4.3.3 General Properties of the Caged-ATP Molecules; 1.4.3.4 Conclusion; 1.4.4 Caged Glutamate; 1.4.4.1 Introduction; 1.4.4.2 Syntheses of the Caged Glutamate Derivatives; 1.4.4.3 General Properties of the Caged-Glutamate Molecules; 1.4.4.4 Conclusion; Abbreviations; References; 2 Mechanistic Overview of Phototriggers and Cage Release; 2.1 Introduction; 2.2 Major Photoremovable Protecting Groups; 2.2.1 2-Nitrobenzyl (2-NB); 2.2.1.1 The Reactive Excited State2.2.1.2 The aci-Nitro IntermediateWith contributions by more than 30 expert researchers, this handbook covers the whole spectrum from chemistry to cell biology and from theory to application. In so doing, it deals with a broad range of topics from the chemistry and biophysics of caged compounds to their application in time-resolved studies, comparing the properties of different caging groups. The authors describe in detail light-activation of proteins as well as nucleic acids, while a special section is devoted to multiphoton phototriggers.A must-have for every biochemist, biophysicist and molecular biologist developing anPhotobiochemistryBiomoleculesSeparationProtective groups (Chemistry)Photobiochemistry.BiomoleculesSeparation.Protective groups (Chemistry)547.2Goeldner Maurice1839544Givens Richard1839545MiAaPQMiAaPQMiAaPQBOOK9911019423603321Dynamic studies in biology4418809UNINA