04021nam 2200733Ia 450 991101938350332120200520144314.0978661040881897812804088161280408812978047024215504702421599780471758044047175804397804717580370471758035(CKB)1000000000327273(EBL)254066(OCoLC)475966527(SSID)ssj0000161351(PQKBManifestationID)11151982(PQKBTitleCode)TC0000161351(PQKBWorkID)10198509(PQKB)10201995(MiAaPQ)EBC254066(Perlego)2760797(EXLCZ)99100000000032727320060912d2006 uy 0engur|n|---|||||txtccrGene-environment interactions fundamentals of ecogenetics /edited by Lucio G. Costa, David L. EatonHoboken, N.J. Wiley-Lissc20061 online resource (577 p.)Description based upon print version of record.9780471467816 0471467812 Includes bibliographical references (p. 451-529) and index.Gene-Environment Interactions; Contents; Foreword; Acknowledgments; Contributors; PART I; Chapter 1. Introduction; Chapter 2. Ecogenetics: Historical Perspectives; Chapter 3. Tools of Ecogenetics; Chapter 4. Epidemiologic Approaches; Chapter 5. Statistical Issues in Ecogenetic Studies; PART II; Chapter 6. Overview of Section II; Chapter 7. Polymorphisms in Cytochrome P450 and Flavin-Containing Monooxygenase Genes; Chapter 8. Polymorphisms in Xenobiotic Conjugation; Chapter 9. Paraoxonase, Butyrylcholinesterase, and Epoxide Hydrolase; Chapter 10. DNA Repair EnzymesChapter 11. Receptors and Ion ChannelsPART III; Chapter 12. Overview of Section III; Chapter 13. Lung Cancer; Chapter 14. Gastrointestinal Cancers; Chapter 15. Neurodegenerative Diseases; Chapter 16. Cardiovascular Disease; Chapter 17. Type 2 Diabetes; Chapter 18. Infectious Disease Ecogenetics; Chapter 19. Genetic Variation, Diet, and Disease Susceptibility; Chapter 20. Genetic Determinants of Addiction to Alcohol, Tobacco, and Drugs of Abuse; PART IV; Chapter 21. Overview of Section IV; Chapter 22. Ethical Issues in Ecogenetics; Chapter 23. Social and Psychological Aspects of EcogeneticsChapter 24. Legal IssuesChapter 25. Risk Assessment and the Impact of Ecogenetics; Bibliography; IndexUnderstanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline, reflecting its relationship with toxicology, epidemiology, pharmacology, public health, and other medical and biological fields.Divided into four sections, the text elucidates key basic and advanced topics:* Section 1 covers fundamentals, including the history of the discipline, a discussion of the molecular laboratory tools currently availableGenetic toxicologyEcological geneticsEnvironmentally induced diseasesGenetic aspectsDisease susceptibilityGenetic aspectsHuman geneticsVariationGenetic toxicology.Ecological genetics.Environmentally induced diseasesGenetic aspects.Disease susceptibilityGenetic aspects.Human geneticsVariation.616.042Costa Lucio G.1954-747662Eaton David L66581MiAaPQMiAaPQMiAaPQBOOK9911019383503321Gene-environment interactions4422618UNINA