03729nam 2200721 a 450 991101922810332120200520144314.09786612122361978128212236912821223639780470513842047051384597804705138590470513853(CKB)1000000000376480(EBL)470477(SSID)ssj0000364333(PQKBManifestationID)11262318(PQKBTitleCode)TC0000364333(PQKBWorkID)10394615(PQKB)11263345(MiAaPQ)EBC470477(Au-PeEL)EBL470477(CaPaEBR)ebr10297888(CaONFJC)MIL212236(OCoLC)181171735(NjHacI)991000000000376480(BIP)001228649(Perlego)2765894(EXLCZ)99100000000037648019890710d1989 uy 0engur|n|---|||||txtccrPhotosensitizing compounds their chemistry, biology and clinical useChichester ;New York Wiley19891 online resource (252 p.)Ciba Foundation symposium ;146"A Wiley-Interscience publication."9780471923084 0471923087 Includes bibliographical references and indexes.PHOTOSENSITIZING COMPOUNDS: THEIR CHEMISTRY, BIOLOGY AND CLINICAL USE; Contents; Introduction; What are the ideal photoproperties for a sensitizer?; The chemistry, photophysics and photosensitizing properties of phthalocyanines; General discussion : Comparison of haematoporphyrin derivative and new photosensitizers; Porphyrins as photosensitizers; Photodynamic therapy: light delivery and dosage for second-generation photosensitizers; In vivo transport and pharmacokinetic behaviour of tumour photosensitizers; Intracellular localization of photosensitizersTissue localization of photosensitizers and the mechanism of photodynamic tissue destructionImmunosuppression in phototherapy; Effects of porphyrins on skin; Photosensitizing compounds in the treatment of psoriasis; Extracorporeal photochemotherapy in the treatment of cutaneous T cell lymphoma and autoimmune disorders affecting the skin; Photodynamic therapy of early-stage lung cancer; Long-term experience with integral photodynamic therapy of TIS bladder carcinoma; Photoradiation therapy of brain tumours; Final general discussion : Drug and light doses for photodynamic therapyChairman's summing-upIndex of contributors; Subject indexCertain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders.Ciba Foundation symposium ;146.Photosensitizing compoundsTherapeutic useTestingCongressesPhotosensitizing compoundsCongressesCancerPhotochemotherapyCongressesPhotosensitizing compoundsTherapeutic useTestingPhotosensitizing compoundsCancerPhotochemotherapy615.8/31MiAaPQMiAaPQMiAaPQBOOK9911019228103321Photosensitizing compounds4419409UNINA