05428nam 22006494a 450 991100657310332120230721030307.01-4356-1025-31-60119-362-9(CKB)1000000000385082(EBL)3382340(SSID)ssj0000071725(PQKBManifestationID)11969757(PQKBTitleCode)TC0000071725(PQKBWorkID)10090634(PQKB)11047674(MiAaPQ)EBC3382340(EXLCZ)99100000000038508220070810d2007 uy 0engur|n|---|||||txtccrDevelopment of a biokinetic model for radionuclide-contaminated wounds and procedures for their assessment, dosimetry, and treatment[electronic resource] recommendations of the National Council on Radiation Protection and Measurements, December 14, 2006Bethesda, MD National Council on Radiation Protection and Measurementsc20071 online resource (428 p.)NCRP report ;no. 156"This report was prepared by Scientific Committee 57-17 on Radionuclide Dosimetry Model for Wounds"--Pref.0-929600-93-2 Includes bibliographical references (p. 346-380) and index.""Cover""; ""Preface""; ""Contents""; ""Executive Summary""; ""1. Introduction""; ""1.1 Background""; ""1.2 Purpose and Scope""; ""2. Skin Biology""; ""2.1 Skin Anatomy""; ""2.1.1 The Epidermis""; ""2.1.2 The Dermis""; ""2.1.3 The Subcutis""; ""2.2 Binding and Transport of Injected Materials""; ""2.2.1 Loose Connective Tissue""; ""2.2.2 Tissue Fluids and Their Contents""; ""2.2.3 Connective Tissue Macrophages""; ""2.2.4 Particle Transport by Macrophages""; ""2.3 Wound Healing""; ""2.3.1 Inflammation""; ""2.3.2 Reepithelialization""; ""2.3.3 Formation of Granulation Tissue""; ""2.3.4 Burns""""2.3.5 Foreign-Body Reactions""""3. Etiology of Radionuclide-Contaminated Wounds""; ""3.1 Industrial Experience""; ""3.2 Military Experience with Depleted Uranium""; ""3.2.1 Introduction""; ""3.2.2 Persian Gulf War Experience""; ""3.2.3 Summary of the U.S. Department of Veterans Affairs Follow-Up Program""; ""3.2.4 Embedded Radioactive Particles and Fragments""; ""3.3 Medical Cases""; ""4. Generic Biokinetic Model for Radionuclides in Wounds""; ""4.1 Implementation of the Wound Biokinetic Model""; ""4.2 Modeling Results""; ""4.2.1 Modeling of Individual Radionuclides""""4.2.2 Modeling of Default Categories of Soluble Radionuclides""""4.3 Retention of Soluble Radionuclides in Other Types of Wounds: Quantitative Comparison with Intramuscular Data""; ""4.3.1 Subcutaneous Injection""; ""4.3.2 Lacerated Skin""; ""4.3.3 Abraded Skin""; ""4.3.4 Intact Skin""; ""4.3.5 Thermally-Burned Skin""; ""4.3.6 Acid-Burned Skin""; ""4.3.7 Radiation-Burned Skin""; ""4.4 Modeling of Radioactive Colloids and Particles""; ""4.4.1 Wound Retention of 239Pu4+ Hydroxide Colloids and Polymers Injected Intramuscularly in Rats and Rabbits and Subcutaneously in Dogs""""4.4.2 Wound Retention of 239PuO2 Particles Injected Subcutaneously in Dogs""""4.4.3 Analysis of the Retention of Other Insoluble Radioactive Particles in Wounds""; ""4.4.4 Summary for Insoluble Radionuclides""; ""4.4.5 Application of the Wound Model to Animal Data for Retention of Fine, Insoluble Radioactive Particles Deposited in Wounds""; ""4.5 Retention of Radioactive Solids in Wounds""; ""4.5.1 Depleted Uranium Metal Fragments Implanted Intramuscularly in Rats""; ""4.5.2 Plutonium Metal Wire Implanted Subcutaneously in Rabbits and Rats""""4.5.3 Minispheres of Nuclear Weapons Test Fallout Contaminated with Plutonium and Americium Implanted Subcutaneously in Rats""""4.5.4 Summary for Solid Radioactive Materials""; ""4.5.5 Application of the Wound Model to Animal Data for Retention of Radionuclides in Implanted Solids""; ""4.6 Default Biokinetic Parameters for Radionuclides in Wounds""; ""5. Exposure Assessment and Dosimetry of Radionuclide-Contaminated Wounds""; ""5.1 Wound Assessment""; ""5.1.1 Wound Monitors""; ""5.1.2 Survey Meters""; ""5.1.3 Sequential Measurements""; ""5.2 Local Dosimetry Models""""5.2.1 Skin (Shallow) Dosimetry Models""NCRP report ;no. 156.Radiation injuriesTreatmentMathematical modelsRadiation dosimetryMathematical modelsRadioisotopesToxicologyMathematical modelsWounds and injuriesComplicationsSkinEffect of radiation onRadiation injuriesTreatmentMathematical models.Radiation dosimetryMathematical models.RadioisotopesToxicologyMathematical models.Wounds and injuriesComplications.SkinEffect of radiation on.362.196/9897National Council on Radiation Protection and Measurements.Scientific Committee 57-17 on Radionuclide Dosimetry Model for Wounds.MiAaPQMiAaPQMiAaPQBOOK9911006573103321Development of a biokinetic model for radionuclide-contaminated wounds and procedures for their assessment, dosimetry, and treatment4390942UNINA