04347nam 22005895 450 991097838250332120250209115235.09783031698002303169800210.1007/978-3-031-69800-2(MiAaPQ)EBC31900416(Au-PeEL)EBL31900416(CKB)37498920200041(DE-He213)978-3-031-69800-2(OCoLC)1499722522(EXLCZ)993749892020004120250209d2024 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierDrug Interactions in Gastroenterology A Clinical Guide /edited by Marko Banić, Damir Erceg1st ed. 2024.Cham :Springer Nature Switzerland :Imprint: Humana,2024.1 online resource (964 pages)Clinical Gastroenterology,2197-77049783031697999 3031697995 Legal Aspects of Drug Use -- Discovery and Preclinical Research -- Clinical Research and Regulatory Review -- Drug Development and Drug Interactions -- Antisecretory Drugs -- Motility Drugs -- Mucosal Protective Agents -- Antibiotics -- Antiinflammatory Drugs -- Adverse Drug Reactions and Drug Interactions -- Types of Drug Interactions -- Enzymes and Transporters Involved in Drug Interactions -- Pharmacogenomics -- Drug-Herbal Interactions -- Drug-Food Ineractions -- How to Avoid Drug Interactions -- Influence of Age on Drug Interactions -- Functional State of Digestive System and Oral Drug Absorption Infections -- Cardiorespiratory Disorders -- Renal Insufficiency -- Hepatal Insufficiency -- Irritable Bowel Syndrome -- Metabolic Disorders -- Immune Mediated Disorders -- CNS Disorders -- Acid Related Disorders -- Intestinal Inflammation -- Liver Disorders -- Pancreato-biliary Disorders -- Motility Disorders.The risk of clinically significant drug interaction rises when a patient increases his intake of medication. While drug interaction can be a prominent cause of illness, in many cases, it can be avoided with proper knowledge and care. This text provides a concise yet comprehensive review of common drug interactions in gastroenterology. The book begins with a preliminary overview of GI drugs, focusing on legal aspects of drug use, clinical research and regulatory review, and drug development. The next section goes over the basic pharmacology of GI drugs, specifically profiling antisecretory drugs, motility drugs, mucosal protective agents, antibiotics, and anti-inflammatory drugs. The third section of the text reviews important aspects of drug interaction; topics covered in this section include the different types of drug interactions, adverse drug reactions and interactions, enzymes and transporters involved in drug interactions, pharmacogenomics, drug-herbal interactions, drug-food interactions, and ways to avoid drug interactions altogether. The book moves on to examine comorbidity and digestive diseases that can result from drug interactions, with particular emphasis on infections, cardiorespiratory disorders, renal insufficiency, IBS, metabolic disorders, and CNS disorders. This section also discusses the influence of age on drug interactions. The final section spotlights comedication that can be used to mitigate disorders caused by drug interactions, specifically reviewing comedication used to treat acid-related disorders, intestinal inflammation, liver disorders, pancreato-biliary disorders, and motility disorders. The text also includes over 100 high-yield illustrations, photographs, and tables.Clinical Gastroenterology,2197-7704Internal medicinePsychiatryInternal MedicinePsychiatryInternal MedicineInternal medicine.Psychiatry.Internal Medicine.Psychiatry.Internal Medicine.615.7045Banić Marko1788565Erceg Damir1788566MiAaPQMiAaPQMiAaPQBOOK9910978382503321Drug Interactions in Gastroenterology4323592UNINA