03684nam 2200601 a 450 991097446190332120251017110115.00-309-21107-71-283-21343-597866132134330-309-21105-0(CKB)2550000000042938(EBL)3378803(MiAaPQ)EBC3378803(Au-PeEL)EBL3378803(CaPaEBR)ebr10488624(CaONFJC)MIL321343(OCoLC)923283637(DNLM)1568301(EXLCZ)99255000000004293820110827d2011 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierGenerating evidence for genomic diagnostic test development workshop Summary /Theresa Wizemann and Adam C. Berger, rapporteurs ; Roundtable on translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies1st ed.Washington, D.C. National Academies Press20111 online resource (100 p.)Description based upon print version of record.0-309-21104-2 Includes bibliographical references.""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Tables, Figures, and Boxes""; ""Abbreviations and Acronyms""; ""1 Introduction""; ""2 Stakeholder Perspectives on Evidence""; ""3 Approaches to Evidence Generation""; ""4 Overcoming Barriers for Evidence Generation""; ""5 Considerations Moving Forward""; ""6 Final Remarks""; ""References""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biographical Sketches""; ""Appendix C: Registered Attendees"""Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health.The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence. Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups."--Publisher's description.GenomicsDiagnosisGene mappingGenomics.Diagnosis.Gene mapping.616.0420027Wizemann Theresa M890630Berger Adam C1120088Institute of Medicine (U.S.).Roundtable on Translating Genomic-Based Research for Health.Institute of Medicine (U.S.).Board on Health Sciences Policy.MiAaPQMiAaPQMiAaPQBOOK9910974461903321Generating evidence for genomic diagnostic test development4447104UNINA