03198nam 2200709 a 450 991097430520332120251117095426.097866136463479781280669415128066941197898143386849814338680(CKB)2550000000101415(EBL)919103(OCoLC)794328398(SSID)ssj0000654709(PQKBManifestationID)12238070(PQKBTitleCode)TC0000654709(PQKBWorkID)10661333(PQKB)10161417(MiAaPQ)EBC919103(WSP)00002654(Au-PeEL)EBL919103(CaPaEBR)ebr10563560(CaONFJC)MIL364634(Perlego)848222(BIP)34142772(EXLCZ)99255000000010141520120607d2012 uy 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierBoron and gadolinium neutron capture therapy for cancer treatment /Narayan S. Hosmane ... [et al.]1st ed.Singapore World Scientific Pub. Co.20121 online resource (271 p.)Description based upon print version of record.9789814338677 9814338672 Includes bibliographical references and index.What is cancer? -- Principles of neutron capture therapy -- Major neutron capture therapy (NCT) drug prototypes -- Neutron sources for NCT -- NCT dosimetry and treatment planning -- Selected in vitro and in vivo studies -- Clinical trials -- Future perspectives for boron and gadolinium neutron capture therapies in cancer treatment -- Clinical state of BNCT by US Department of Energy (DOE) as at 1997.The book focuses on two concurrent experimental therapies in cancer treatment known as boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT) using a variety of boron- and gadolinium-based compounds. Some of the gadolinium compounds serve the dual purpose as being MRI contrast agents and GdNCT agents. The book describes why BNCT & GdNCT were not at the forefront of the clinical trials during the past seven to eight decades since the discovery of neutrons by John Chadwick in 1932 and how the latest development in the synthesis of target boron- and gadolinium-based drugs has turned the area into the hottest one worthy of further investigation with the new clinical trials in the USA and elsewhere.CancerTreatmentBoron-neutron capture therapyBoronGadoliniumCancerTreatment.Boron-neutron capture therapy.Boron.Gadolinium.616.9940642Hosmane Narayan S858251Hosmane Narayan S858251MiAaPQMiAaPQMiAaPQBOOK9910974305203321Boron and gadolinium neutron capture therapy for cancer treatment4469230UNINA