06697nam 2200673Ia 450 991097362030332120251117065807.01-61122-383-0(CKB)2670000000092445(EBL)3018655(SSID)ssj0000524411(PQKBManifestationID)11355966(PQKBTitleCode)TC0000524411(PQKBWorkID)10547460(PQKB)10162259(MiAaPQ)EBC3018655(Au-PeEL)EBL3018655(CaPaEBR)ebr10661593(OCoLC)726743253(BIP)32205586(EXLCZ)99267000000009244520100823d2011 uy 0engur|n|---|||||txtccrNeuroplasticity in the auditory brainstem from physiology to the drug therapy /Angelo Salami. editor1st ed.New York Nova Science Publishersc20111 online resource (191 p.)Neurology : laboratory and clinical research developmentsPharmacology : research, safety testing and regulationDescription based upon print version of record.1-61761-949-3 Includes bibliographical references and index.Intro -- NEUROPLASTICITY IN THE AUDITORY BRAINSTEM: FROM PHYSIOLOGY TO THE DRUG THERAPY -- NEUROPLASTICITY IN THE AUDITORY BRAINSTEM: FROM PHYSIOLOGY TO THE DRUG THERAPY -- Contents -- Introduction -- Chapter I Anatomy of the Auditory Pathway -- Abstract -- 1. The Inner Ear -- 2. The Auditory Nerve -- 3. The Central Auditory Pathway -- 3.1. The Cochlear Nuclear Complex (CNC) -- 3.2. Superior Olivary Complex (SOC) -- 3.3. Inferior Colliculus (IC) -- 4. Central Pathways and Cortical Projections -- 5. The Primary Auditory Cortex (PAC, AI) -- 6. Efferent Projections -- 6.1. From the AC to both the MBG and IC -- 6.2. From the IC to both Cochlear Nuclei (CN) and the SOC -- 6.3. From the SOC to the Hair Cells -- References -- Chapter II Phsyiology of the Central Auditory System -- Introduction -- Central Auditory Processing Strategies -- Spontaneous Rat -- Intensity Coding -- Frequency Coding -- Temporal Coding -- Sound Localization -- Complex Stimuli -- Variation in the Physiology of the Normal Central Auditory Pathway -- Anesthesia -- Development -- Attention -- Conclusions -- Acknowledgments -- References -- Chapter III Neurobiology of Age Related Hearing Loss -- Abstract -- Introduction -- Neurobiology -- Neurotrophins -- Mitochondrial Modifications -- Other Mechanisms of Mitochondrial Damage are Related to Lipid Oxidation and Protein Oxidation -- Discussion -- Conclusion -- References -- Chapter IV Neuroplasticity in the Auditory System after Hearing Loss -- Abstract -- Introduction -- Molecular Mechanisms of Neuroplasticity -- Neuroplasticity and Auditory System -- Neurons, Growth Cones and Neuroplasticity -- Neuroplasticity and Experimental Deafness by Cochlear Induced Lesion -- 1. First Phase: Acute Cochlear Nuclei Degeneration [5,6] -- 2. Second Phase: Stabilization of Lesions and Neuroplasticity.3. Third Phase: Neuroplasticity and CN Reorganization -- Conclusion -- Acknowledgments -- References -- Chapter V Hearing Loss and Balance Dysfunction in Children -- Introduction -- Sensorineural Hearing Loss -- 1. Balance and Vestibular Dysfunction in SHNL -- 2. Cochlear Implantation and Vestibular Function -- Conductive Hearing Loss -- Rehabilitation of Balance and Motor Skills in the Hearing Impaired Child -- Conclusion -- References -- Chapter VI The Effect of Brain Plasticity on the Results of Cochlear Implantation -- Abstract -- 1. The Importance of Brain Research in Deaf Patients -- 2. Cross-Modal Plasticity -- 3. Method Used to Evaluate Human Brain Function -- 4. PET Studies in Deaf Patients -- 4.1. Cortical Metabolism in Prelingually Deaf Children -- 4.2. Cortical Metabolism in Postlingually Deaf Adults -- 4.3. The Association between Cortical Metabolism and Post-implant Speech Perception in the Prelingually Deaf -- 4.4. Changes in Cortical Metabolism after Cochlear Implantation -- 5. Changes in Cognitive Function in Deaf Patients -- 6. Studies Using Deaf Animal Models -- 6.1. Changes in Auditory Cortex Metabolism in the White Rat Model -- 6.2. Molecular Changes in the Auditory Cortex of a Deaf White Rat Model -- 6.3. Electrophysiologic and Metabolic Changes in the Auditory Cortex in a Deaf Cat Model -- 7. Summary and Future Research Directions -- Conclusion -- Acknowledgments -- References -- Chapter VII Pharmacology of New Drugs Used to Improve the Neuroplasticity of the Central Auditory Pathway -- Abstract -- Introduction -- Coenzyme Q10 -- Basic Pharmacology and Toxicity -- Coenzyme Q10 and Neuroprotection -- Experimental and Clinical Data -- Q-TER®: A Water-soluble Formulation of CoQ10 -- Citicoline -- Synthesis of Membrane Phospholipids -- Neurotransmitter Production -- Basic Pharmacology and Toxicity.Experimental and Clinical Data -- Conclusion -- References -- Chapter VIII New Drugs to Improve the Neuroplasticity of the Central Auditory Pathway -- Abstract -- Introduction -- Antioxidant Agents -- Methods -- Results -- Discussion -- Conclusion -- References -- Chapter IX Central Auditory System Neuroplasticity and Hippocampal Neurogenesis following Cochlear Insults -- Abstract -- Introduction -- Salicylate-Induced Cochlear Insult -- Acute Salicylate Exposure -- Chronic Salicylate Exposure -- Carboplatin-induced Ototoxicity -- Acoustic Overstimulation -- Conclusion -- Acknowledgments -- References -- Index -- Blank Page.According to the theory of neuroplasticity, thinking, learning, acting and hearing can change both the brain's physical structure and functional organisation according to the peripheral stimuli. This book reviews the knowledge on the neuroplasticity in the auditory brainstem: from physiology to the drug therapy.Neurology--laboratory and clinical research development series.Pharmacology-research, safety testing, and regulation series.Auditory pathwaysNeuroplasticityBrain stemCochlear implantsAuditory pathways.Neuroplasticity.Brain stem.Cochlear implants.612.8/5Salami Angelo1867066MiAaPQMiAaPQMiAaPQBOOK9910973620303321Neuroplasticity in the auditory brainstem4474493UNINA01621oas 22005773 450 991068253840332120260203213014.02576-537X(DE-599)ZDB2971542-8(OCoLC)1019427552(CONSER) 2018201131(CKB)4100000007372820(EXLCZ)99410000000737282020180112b20182025 ua aengur|||||||||||txtrdacontentcrdamediacrrdacarrierThe Air Force journal of Indo-Pacific affairsMaxwell AFB, AL:Air University Press,[2018]-2576-5361 Journal of Indo-Pacific affairsJIPAAir forcesPeriodicalsAir forcesfast(OCoLC)fst00802378Strategic aspects of individual placesfast(OCoLC)fst01355062Indo-Pacific RegionStrategic aspectsPeriodicalsIndo-Pacific RegionfastOnline resources.Periodicals.fastAir forcesAir forces.Strategic aspects of individual places.320.9Air University (U.S.).Press,DLCDLCDLCGPOMERUCOCLCFVT2DLCOCLCQOCLCLDLCJOURNAL9910682538403321The Air Force journal of Indo-Pacific affairs4409811UNINA