04655nam 2200805Ia 450 991096540860332120251017110106.00-309-16583-01-280-17595-897866101759560-309-54451-3(CKB)1000000000017865(EBL)3377810(SSID)ssj0000283921(PQKBManifestationID)11236696(PQKBTitleCode)TC0000283921(PQKBWorkID)10250609(PQKB)11399278(MiAaPQ)EBC3377810(Au-PeEL)EBL3377810(CaPaEBR)ebr10072138(CaONFJC)MIL17595(OCoLC)923273265(DNLM)1231404(BIP)53860202(BIP)11152699(EXLCZ)99100000000001786520041006d2005 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierScaling up treatment for the global AIDS pandemic challenges and opportunities /Committee on Examining the Probable Consequences of Alternative Patterns of Widespread Antiretroviral Drug Use in Resource-Constrained Settings, Board on Global Health ; James Curran ... [et al.], editors1st ed.Washington, DC National Academies Pressc20051 online resource (344 p.)Description based upon print version of record.Print version: Institute of Medicine (U.S.). Committee on Examining the Probable Consequences of Alternative Patterns of Widespread Antiretroviral Drug Use in Resource-Constrained Settings. Scaling up treatment for the global AIDS pandemic. Washington, DC : National Academies Press, ©2005 (DLC) 2004023710 0-309-09264-7 Includes bibliographical references.Opportunities and challenges -- Lessons learned -- Principles of scale-up -- Managing scale-up of antiretroviral therapy -- The path forward.An estimated forty million people carry the human immunodeficiency virus (HIV), and five million more become newly infected annually. In recent years, many HIV-infected patients in wealthy nations have enjoyed significantly longer, good-quality lives as a result of antiretroviral therapy (ART). However, most infected individuals live in the poorest regions of the world, where ART is virtually nonexistent. The consequent death toll in these regions-especially sub-Saharan Africa-is begetting economic and social collapse. To inform the multiple efforts underway to deploy antiretroviral drugs in resource-poor settings, the Institute of Medicine committee was asked to conduct an independent review and assessment of rapid scale-up ART programs. It was also asked to identify the components of effective implementation programs. At the heart of the committee's report lie five imperatives: Immediately introduce and scale up ART programs in resource-poor settings. Devise strategies to ensure high levels of patient adherence to complicated treatment regimens. Rapidly address human-resource shortages to avoid the failure of program implementation. Continuously monitor and evaluate the programs to form the most effective guidelines and treatment regimens for each population. Prepare to sustain ART for decades. AIDS (Disease)AIDS (Disease)Developing countriesAntiretroviral agentsDeveloping countriesHighly active antiretroviral therapyHIV Infectionsdrug therapy(DNLM)D015658Q000188Antiretroviral Therapy, Highly Active(DNLM)D023241Disease Outbreaksprevention & control(DNLM)D004196Q000517Health Planningorganization & administration(DNLM)D006285Q000458Acquired Immunodeficiency Syndrome(DNLM)D000163AIDS (Disease)AIDS (Disease)Antiretroviral agentsHighly active antiretroviral therapy.HIV Infectionsdrug therapy.Antiretroviral Therapy, Highly Active.Disease Outbreaksprevention & control.Health Planningorganization & administration.Acquired Immunodeficiency Syndrome.362.196/9792/0091724Curran James W1831782MiAaPQMiAaPQMiAaPQBOOK9910965408603321Scaling up treatment for the global AIDS pandemic4404663UNINA