04283nam 2200721 a 450 991096101720332120251017110114.0978661018645797803091737970309173795978128018645512801864539780309580526030958052897805851557600585155763(CKB)110986584752358(OCoLC)44964205(CaPaEBR)ebrary10056980(SSID)ssj0000169499(PQKBManifestationID)11155450(PQKBTitleCode)TC0000169499(PQKBWorkID)10204121(PQKB)10270561(Au-PeEL)EBL3376703(CaPaEBR)ebr10056980(OCoLC)817959237(MiAaPQ)EBC3376703(Perlego)4736367(DNLM)894627(BIP)47693827(EXLCZ)9911098658475235819981029d1998 uy 0engurcn|||||||||txtccrHealth effects of exposure to low levels of ionizing radiations time for reassessment? /Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations, Board on Radiation Effects Research, Commission on Life Sciences, National Research Council1st ed.Washington, D.C. National Academy Press19981 online resource (86 p.) BEIR ;7The Compass seriesBibliographic Level Mode of Issuance: Monograph9780309061766 0309061768 Includes bibliographical references (p. 51-72) and index.Health Effects of Exposure to Low Levels of Ionizing Radiations -- Copyright -- Preface -- Contents -- EXECUTIVE SUMMARY -- 1 INTRODUCTION -- 2 EPIDEMIOLOGIC INVESTIGATIONS -- NEW EPIDEMIOLOGIC RESULTS -- ADVANCES IN METHODOLOGY -- CONSIDERATIONS FOR A BEIR VII PHASE-2 COMMITTEE -- RADIOEPIDEMIOLOGIC TABLES -- 3 CELLULAR AND MOLECULAR CONSIDERATIONS -- DNA DAMAGE AND ITS REPAIR -- CONCLUSIONS -- CONDITIONED AND INDUCIBLE RESPONSES TO RADIATION -- CONCLUSIONS -- CHROMOSOMAL ABERRATIONS AND MUTATIONS -- Chromosomal Aberrations -- Mutations -- CONCLUSIONS -- 4 ANIMAL STUDIES -- CONCLUSIONS -- 5 RADIOBIOLOGIC PRINCIPLES AND RISK MODELING -- LINEARITY VERSUS CURVILINEARITY -- THE DOSE DEPENDENCE OF RBE -- POTENTIAL IMPACT OF NEUTRONS -- CONCLUSIONS -- 6 MATHEMATICAL MODELS OF RADIATION CARCINOGENESIS -- THE TWO-MUTATION MODEL -- IMPLICATIONS OF THE MODEL FOR RISK ESTIMATION -- CONCLUSIONS -- LITERATURE CITED -- Information on Committee Members -- List of Acronyms -- ACKNOWLEDGMENTS.The US Environmotection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment.BEIR (Series) ;7.Compass series (Washington, D.C.)Low-level radiationHealth aspectsLow-level radiationHealth aspects.616.9/897National Research Council (U.S.).Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations.MiAaPQMiAaPQMiAaPQBOOK9910961017203321Health effects of exposure to low levels of ionizing radiations4359557UNINA