02849oam 2200601I 450 991096095420332120251117093735.01-4987-5298-51-315-37435-81-4665-6551-910.1201/9781315374352 (CKB)3710000001387623(MiAaPQ)EBC4862400(Au-PeEL)EBL4862400(CaPaEBR)ebr11386621(CaONFJC)MIL1011650(OCoLC)987790994(FINmELB)ELB147465(BIP)59529993(BIP)39568030(EXLCZ)99371000000138762320180706h20172017 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierAlgorithms for next-generation sequencing /Wing-Kin Sung1st ed.Boca Raton, FL :CRC Press, Taylor & Francis Group,[2017]©20171 online resource (347 pages) illustrationsChapman & Hall/CRC Mathematical and Computational Biology Series"A Chapman & Hall book."1-4665-6550-0 Includes bibliographical references and index.1. Introduction -- 2. NGS file formats -- 3. Related algorithms and data structures -- 4. NGS read mapping -- 5. Genome assembly -- 6. Single nucleotide variation (SNV) calling -- 7. Structural variation calling -- 8. RNA-seq -- 9. Peak calling methods -- 10. Data compression techniques used in NGS files.Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before - as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for Next-Generation Sequencing is an invaluable tool for students and researchers in bioinformatics and computational biology, biologists seeking to process and manage the data generated by next-generation sequencing, and as a textbook or a self-study resource. In addition to offering an in-depth description of the algorithms for processing sequencing data, it also presents useful case studies describing the applications of this technology.Chapman and Hall/CRC mathematical & computational biology series.BioinformaticsNucleotide sequenceGenetic algorithmsBioinformatics.Nucleotide sequence.Genetic algorithms.570.285Sung Wing-Kin1865911FlBoTFGFlBoTFGBOOK9910960954203321Algorithms for next-generation sequencing4481014UNINA