05270nam 22006374a 450 991083060640332120230617031205.01-280-25276-697866102527630-470-35602-20-471-32641-00-471-72272-3(CKB)1000000000019018(EBL)226552(OCoLC)58901824(SSID)ssj0000167275(PQKBManifestationID)11163655(PQKBTitleCode)TC0000167275(PQKBWorkID)10169422(PQKB)10156312(MiAaPQ)EBC226552(EXLCZ)99100000000001901820020715d2003 uy 0engur|n|---|||||txtccrHandbook of comparative genomics[electronic resource] principles and methodology /Cecilia Saccone, Graziano PesoleNew York Wiley-Lissc20031 online resource (444 p.)Description based upon print version of record.0-471-39128-X Includes bibliographical references (p. 377-422) and index.HANDBOOK OF COMPARATIVE GENOMICS Principles and Methodology; CONTENTS; PREFACE; I GENOME FEATURES; 1 PROKARYOTES; 1.1 Introduction; 1.2 Morphology and Classification; 1.3 Genome Shape and Size; 1.4 Gene Content and Organization; 1.5 Base Composition; 1.6 Codon Use; 1.7 Replication and Expression; 2 EUKARYOTES; 2.1 Introduction; 2.2 Classification and Time Scale; 2.3 Genome Shape and Size; 2.4 Base Composition; 2.5 Replication, Repair, and Recombination; 2.6 Gene Expression; 2.6.1 Transcription and Posttranscriptional Regulation; 2.6.2 Genetic Code and Codon Use2.6.3 Translation and Posttranslation Modifications2.7 Completely Sequenced Eukaryotic Genomes; 2.7.1 Saccharomyces cerevisiae Genome; 2.7.2 Schizosaccharomyces pombe Genome; 2.7.3 Caenorhabditis elegans Genome; 2.7.4 Drosophila melanogaster Genome; 2.7.5 Arabidopsis thaliana Genome; 2.7.6 Oryza sativa Genome; 2.7.7 Homo sapiens Genome; 3 ORGANELLES; 3.1 Mitochondria; 3.1.1 General Structure and Function; 3.1.2 DNA and Genetic System; 3.1.3 Genome Features; 3.2 Chloroplasts and Other Plastids; II METHODOLOGIES; 4 MOLECULAR BIOLOGY TECHNIQUES FOR GENOMICS; 4.1 Genome DNA Sequencing4.1.1 DNA-Sequencing Techniques4.1.2 The Human Genome Project; 4.2 Analysis of the Transcriptome; 4.2.1 Analysis of Gene Expression; 4.2.2 Expressed Sequence Tags; 4.2.3 Serial Analysis of Gene Expression; 4.2.4 Differential Display; 4.2.5 Representational Difference Analysis; 4.2.6 DNA Microarrays; 4.3 Analysis of the Proteome; 4.3.1 Two-Dimensional Gel Electrophoresis; 4.3.2 Protein Identification; 4.3.3 Study of Protein-DNA and Protein-Protein Interactions; 4.3.4 Proteome Analysis Using Biochips; 5 BIOLOGICAL DATABASES IN THE GENOME ERA; 5.1 Introduction5.2 Primary and Specialized Databases5.3 Database Structures; 5.4 Linked Databases and Database Interoperability; 5.5 Database Annotation; 5.6 Retrieval Systems; 5.6.1 SRS; 5.6.2 Entrez; 5.6.3 Other Retrieval Systems; 5.7 Nucleotide Databases; 5.8 Protein Databases; 5.9 Other Protein Databases; 5.10 Genomic Databases and Resources; 5.11 Gene Databases and Resources; 5.12 Transcriptome Databases; 5.13 Metabolism Databases; 5.14 Mutation Databases; 5.15 Mitochondrial Databases and Resources; 6 COMPUTATIONAL METHODS FOR THE ANALYSIS OF GENOME SEQUENCE DATA; 6.1 Introduction; 6.2 Dot-Plot Matrix6.3 Sequence Pairwise Alignment6.3.1 Needleman-Wunsch Global Alignment Algorithm; 6.3.2 Smith-Waterman Algorithm for the Identification of Common Molecular Subsequences; 6.3.3 Alignment of cDNA and Genomic DNA Sequences; 6.3.4 Genome Alignment; 6.3.5 Cleanup of Sequence Databases from Redundancy; 6.3.6 Measure of the Similarity Degree between Homologous Sequences; 6.4 Database Searching; 6.4.1 FASTA; 6.4.2 BLAST; 6.4.3 BLAST and FASTA Family of Programs; 6.4.4 Filtering Matches to Unwanted Sequences; 6.4.5 Filtering Matches to Repetitive Sequences6.4.6 Statistical Significance of Alignment ScoresThis comprehensive reference covers the comparative methodology involved in studying molecular evolution. Providing a practical introduction to the role of bioinformatics in comparative genomics, this publication further discusses the basic technology used in genome sequencing projects and provides an overview of genome storage databases currently in use. This timely and cutting-edge text also:Reviews the basic principles of genomics and gene expression analysis Discusses analytic methods in proteomics and transcriptomics Includes a comprehensive list of Web resourceGenomicsHandbooks, manuals, etcEvolutionary geneticsHandbooks, manuals, etcGenomicsEvolutionary genetics572.8572.86Saccone C623770Pesole Graziano286145MiAaPQMiAaPQMiAaPQBOOK9910830606403321Handbook of comparative genomics1462206UNINA04622nam 2200637 a 450 991096007620332120200520144314.097866101928929780309176347030917634497812801928901280192895978030958800303095880069780585143200058514320X(CKB)110986584751608(SSID)ssj0000251204(PQKBManifestationID)11238824(PQKBTitleCode)TC0000251204(PQKBWorkID)10249322(PQKB)11400525(MiAaPQ)EBC3376335(Au-PeEL)EBL3376335(CaPaEBR)ebr10055466(OCoLC)923262984(Perlego)4736801(EXLCZ)9911098658475160819960705d1996 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierStatistics on U.S. immigration an assessment of data needs for future research /Barry Edmonston, editor ; Committee on National Statistics and Committee on Population, Commission on Behavioral and Social Sciences and Education, National Research Council1st ed.Washington, D.C. National Academy Pressc19961 online resource (x, 91 pages) illustrations, chartsBibliographic Level Mode of Issuance: Monograph9780309052757 0309052750 Includes bibliographical references (p. 82-85).Statistics on U.S. Immigration -- Copyright -- Acknowledgments -- Contents -- Summary -- CONCLUSIONS -- Research Issues -- Research Improvements -- RECOMMENDATIONS -- Parental Nativity -- Public Use Microdata Sample -- Current Population Survey -- Joint Mexico-United States Surveys -- Immigration and Naturalization Service Records -- A Longitudinal Survey -- 1 Introduction -- INTEREST IN IMMIGRATION ISSUES -- SHIFTS IN IMMIGRATION PATTERNS -- Immigration Today -- Perceptions of the Past -- Effects of Immigration -- ESTABLISHING DATA PRIORITIES -- ADEQUACY OF IMMIGRATION DATA -- DEFINITION OF TERMS -- ORGANIZATION OF THE REPORT -- 2 Trends in U.S. Immigration -- A DEMOGRAPHIC PERSPECTIVE -- Trends Since 1900 -- Data Needs -- AN ECONOMIC PERSPECTIVE -- Economic Trends -- Data Needs -- 3 Effects of Immigration and Assimilation -- SOCIAL POLICY AND WELFARE -- Employment and Income Dynamics -- The Context of Immigration -- Comparing Political and Economic Immigration -- Effects of Amnesty -- Research Issues -- Perinatal Health -- MENTAL HEALTH -- EDUCATIONAL ATTAINMENT -- RESEARCH NEEDS -- DATA NEEDS -- 4 Labor Force Issues -- ECONOMIC ASPECTS OF IMMIGRATION -- WAGE TRENDS -- IMMIGRANTS AND EMERGING INDUSTRIES -- RESEARCH ISSUES -- 5 Social and Family Networks -- IMMIGRATION NETWORKS -- IMMIGRATION AND THE FAMILY -- RESEARCH ISSUES -- DATA NEEDS -- 6 Immigration Data Needs -- DECENNIAL CENSUS -- CURRENT POPULATION SURVEY -- IMMIGRATION AND NATURALIZATION SERVICE RECORDS -- CASE STUDIES -- DATA ON NATIONALITY, RACE, AND ETHNICITY -- 7 Longitudinal Studies of Immigrants -- ADVANTAGES AND DISADVANTAGES -- ALTERNATIVES TO A LONGITUDINAL SURVEY OF IMMIGRANTS -- SPECIAL-PURPOSE IMMIGRANT SURVEYS -- NEED FOR LONGITUDINAL DATA -- References -- Appendix Workshop on U.S. Immigration Statistics: An Assessment of Data Needs for Future Research -- AGENDA.PAPERS PRESENTED AT THE WORKSHOP -- WORKSHOP PARTICIPANTS -- National Research Council Staff.The growing importance of immigration in the United States today prompted this examination of the adequacy of U.S. immigration data. This volume summarizes data needs in four areas: immigration trends, assimilation and impacts, labor force issues, and family and social networks. It includes recommendations on additional sources for the data needed for program and research purposes, and new questions and refinements of questions within existing data sources to improve the understanding of immigration and immigrant trends.United StatesEmigration and immigrationStatistical methodsEdmonston Barry147843National Research Council (U.S.).Committee on National Statistics.National Research Council (U.S.).Committee on Population.MiAaPQMiAaPQMiAaPQBOOK9910960076203321Statistics on U.S. immigration4361319UNINA