00840nam0-2200313---450-99000911377040332120091106154711.01874572801000911377FED01000911377(Aleph)000911377FED0100091137720091106d1995----km-y0itay50------baengGBa-------001yyGay lettersJames Jolly, Estelle Kohlerforeword by Sir Ian McKellenLondonMarginalia Press1995XV, 173 p.ill.22 cmNarrativajolly,James506304Kohler,Estelle506305ITUNINARICAUNIMARCBK990009113770403321G 1/82DMNUPDMNUPGay letters780937UNINA02635nam 2200601 a 450 991095975520332120251117091625.01-61668-374-0(CKB)2550000000059365(EBL)3020247(SSID)ssj0000568957(PQKBManifestationID)12273075(PQKBTitleCode)TC0000568957(PQKBWorkID)10536657(PQKB)11368720(MiAaPQ)EBC3020247(Au-PeEL)EBL3020247(CaPaEBR)ebr10676408(OCoLC)923663273(BIP)28923359(EXLCZ)99255000000005936520100114d2010 uy 0engur|n|---|||||txtccrDiscrete optimization for TSP-like genome mapping problems /D. Mester ... [et al.]1st ed.New York Nova Science Publishers, Inc.c20101 online resource (74 p.)Genetics--research and issuesNovinka"Nova biomedical"--cover.1-61668-170-5 Includes bibliographical references (p. [53]-58) and index.Guided evolution strategy algorithm for classic TSP as a basis for solving the genetic/genomic TSP-like problems -- Multilocus genetic mapping -- Multilocus consensus genetic mapping : formulation, model and algorithms -- TSP-like problem in physical mapping (PMP).This book introduces a discrete optimization technique in four applications: classic Traveler Salesperson Problem (TSP), Multilocus Genetic Mapping, Multilocus Consensus Genetic Mapping, and Physical Mapping. Each of the four sections contains the problem formulation, description of the algorithm, and experimental results. The foregoing problems are solved on the basis of Guided Evolution Strategy (GES) algorithm. The algorithm was implemented in MultiPoint package (http: //multiqtl.com). The developed analytical tools were applied in many genome mapping projects.Genetics--research and issues series.Novinka (Series)Gene mappingMathematical modelsMathematical optimizationGene mappingMathematical models.Mathematical optimization.572.8/633Mester D(David)1866189MiAaPQMiAaPQMiAaPQBOOK9910959755203321Discrete optimization for TSP-like genome mapping problems4473541UNINA