03453nam 2200661Ia 450 991095722480332120251116233311.09780300189551030018955910.12987/9780300189551(CKB)2560000000102340(EBL)3421237(SSID)ssj0000892588(PQKBManifestationID)12401245(PQKBTitleCode)TC0000892588(PQKBWorkID)10897708(PQKB)10381331(StDuBDS)EDZ0000157963(MiAaPQ)EBC3421237(DE-B1597)485765(OCoLC)849928778(DE-B1597)9780300189551(Au-PeEL)EBL3421237(CaPaEBR)ebr10718693(CaONFJC)MIL496066(OCoLC)923603850(Perlego)1089144(OCoLC)849928778(EXLCZ)99256000000010234020121107d2013 uy 0engur|nu---|u||utxtccrRisk, chance, and causation investigating the origins and treatment of disease /Michael B. Bracken1st ed.New Haven Yale University Pressc20131 online resource (288 p.)Description based upon print version of record.9780300188844 0300188846 Includes bibliographical references and index.Front matter --Contents --Acknowledgments --Abbreviations --One. Risk, Chance, and Causation --Two. Chance and Randomness --Three. Risk --Four. Randomization and Clinical Trials --Five. More Trials and Some Tribulations --Six. Harm --Seven. Screening, Diagnosis, and Prognosis --Eight. A Statistical Sojourn --Nine. Disease Clusters --Ten. Genetics and the Genome --Eleven. The Study of Mankind Is Man --Twelve. Celebrity Trumps Science --Thirteen. Replication and Pooling --Fourteen. Bias in Publication and Reporting --Fifteen. Causes --Sixteen. Ultimate Causation --Notes --Bibliography and Further Reading --IndexThe press and other media constantly report news stories about dangerous chemicals in the environment, miracle cures, the safety of therapeutic treatments, and potential cancer-causing agents. But what exactly is actually meant by "increased risk"-should we worry if we are told that we are at twice the risk of developing an illness? And how do we interpret "reduced risk" to properly assess the benefits of noisily touted dietary supplements? Demonstrating the difficulty of separating the hype from the hypothesis, noted epidemiologist Michael Bracken clearly communicates how clinical epidemiology works. Using everyday terms, Bracken describes how professional scientists approach questions of disease causation and therapeutic efficacy to provide readers with the tools to help them understand whether warnings of environmental risk are truly warranted, or if claims of therapeutic benefit are justified.EpidemiologyTherapeuticsEpidemiology.Therapeutics.616.07/1Bracken Michael B.1942-1809649MiAaPQMiAaPQMiAaPQBOOK9910957224803321Risk, chance, and causation4360554UNINA