00984cam0 2200277 450 E60020004577020200727130450.020090224d1977 |||||ita|0103 baitaITCome lavora uno storicoCarlo G. Hempelcur. Dario AntiseriRomaArmando1977119 p.22 cmMetodologia delle scienze e filosofia del linguaggio3001LAEC000211172001 *Metodologia delle scienze e filosofia del linguaggio3Hempel, Carl G.A600200052979070540878Antiseri, DarioAF00003586070ITUNISOB20200727RICAUNISOBUNISOB10031614E600200045770M 102 Monografia moderna SBNM100001028Si31614acquistopregresso2UNISOBUNISOB20090224111238.020200727130424.0AlfanoCome lavora uno storico1682213UNISOB01026cam0 2200277 450 E60020002245320210503082147.020061107d2001 |||||ita|0103 baitaIT<<La >>distruzione creatriceStrategie di discontinuità e trasformazione per le imprese che vogliono conservare l'eccelenzaRichard N.FosterSarah Kaplan; Pref. Umberto BertelèMilanoEtasc2001XVIII, 396 p.22 cmManagement001LAEC000186742001 *ManagementFoster, Richard N.A600200038929070125635Kaplan, SarahA600200038653070ITUNISOB20210503RICAUNISOBUNISOB330131885E600200022453M 102 Monografia moderna SBNM330001552SI131885acquistocatenacciUNISOBUNISOB20061107085729.020210503082132.0AlfanoDistruzione creatrice1691403UNISOB05390nam 2200721Ia 450 991095720090332120200520144314.097866124915429781282491540128249154797808138205520813820553(CKB)2520000000007927(EBL)484818(OCoLC)593240077(SSID)ssj0000335889(PQKBManifestationID)11929245(PQKBTitleCode)TC0000335889(PQKBWorkID)10278066(PQKB)10942881(MiAaPQ)EBC484818(Au-PeEL)EBL484818(CaPaEBR)ebr10361325(CaONFJC)MIL249154(Perlego)2755024(EXLCZ)99252000000000792720091007d2010 uy 0engurcn|||||||||txtccrClinical research in oral health /[edited by] William V. Giannobile, Brian A. Burt, Robert J. Genco1st ed.Ames, IA Wiley-Blackwell20101 online resource (394 p.)Description based upon print version of record.9780813815299 0813815290 Includes bibliographical references and index.Clinical Research in Oral Health; Contents; Contributors; Preface; Acknowledgments; 1 Clinical and translational research: implications in the promotion of oral health; 1.1 Challenges to the translation of clinical research to clinical practice; 1.2 Health technology assessments-identifying research priorities for oral health research; 1.3 Comparative-effectiveness research (CER); 2 Ethics in oral health research; 2.1 Introduction; 2.2 Ethical foundations; 2.3 Is it human subjects research?; 2.4 Federal regulations2.5 The Institutional and Ethical Review Board (IRB) for studies related to oral health 2.6 Informed consent; 2.7 Vulnerable populations; 2.8 Privacy, confidentiality, and HIPAA; 2.9 Oral health clinical research; 2.10 Conclusion; 3 Responsibilities of institutions and individuals in clinical research in the oral health sciences; 3.1 Governmental and institutional regulations, policies, and guidelines; 3.2 Educational responsibilities of institutions; 3.3 Financial responsibilities of institutions; 3.4 Responsibilities of investigators for FDA-regulated clinical research3.5 Intellectual property and clinical research 3.6 Authorship; 3.7 Scientific misconduct; 3.8 Conflicts of interest (COI); 3.9 Concluding remarks; 4 Regulatory process for the evaluation of dental drugs, devices, and biologics; 4.1 Mission of FDA; 4.2 FDA nomenclature; 4.3 Different pathways to approval; 4.4 Approved and non-approved dental-related products; 4.5 Regulatory processes in Canada, Europe, and other countries; 4.6 Summary; 5 Clinical and translational research grantsmanship: funding opportunities and obtaining research support; 5.1 Introduction and chapter overview5.2 Funding sources and opportunities 5.3 Grant-writing basics and developing research proposals; 5.4 Oversight of funded clinical research; 5.5 Conclusion; 6 Data management in oral health research; 6.1 Introduction; 6.2 Developing a data management plan; 6.3 Defining variables; 6.4 Preparing the database for data entry; 6.5 Using the database for data collection; 6.6 Using the data for analyses; 7 Hypothesis testing and avoiding false-positive conclusions; 7.1 Introduction; 7.2 How can hypothesis testing lead to an overabundance of false-positive leads?7.3 Quantifying the false-positive rates the theory; 7.4 Minimizing false-positive conclusions; registries, surrogates, randomization; 7.5 Conclusion; 8 Outcomes in oral health research; 8.1 Introduction; 8.2 Classification of outcomes; 8.3 Measurements of outcomes; 8.4 Dental and oral health outcomes in clinical research; 8.5 Outcomes and causal pathways; 8.6 Final comments; 9 Examiner training: standardization and calibration in periodontal studies; 9.1 Rationale; 9.2 Instruments; 9.3 Components of assessment; 9.4 Bleeding on probing; 9.5 Probing pressure and probe angulation9.6 Patterns of examiner biasClinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.DentistryResearchTeethCare and hygieneResearchDentistryResearch.TeethCare and hygieneResearch.617.522617.60072Giannobile William V1805692Genco Robert J1805693Burt Brian A1805694MiAaPQMiAaPQMiAaPQBOOK9910957200903321Clinical research in oral health4354427UNINA