03441nam 2200685Ia 450 991095314710332120200520144314.01-04-022210-20-429-27124-71-4822-8341-71-280-07237-70-203-30427-6978661007237810.4324/9781482283419 (CKB)1000000000255939(EBL)172381(OCoLC)475879893(SSID)ssj0000285184(PQKBManifestationID)12113797(PQKBTitleCode)TC0000285184(PQKBWorkID)10262241(PQKB)10555437(Au-PeEL)EBL172381(CaPaEBR)ebr10061048(CaONFJC)MIL7237(OCoLC)1000438508(MiAaPQ)EBC172381(EXLCZ)99100000000025593919990607d1999 uy 0engur|n|---|||||txtccrUsing CNS autopsy tissue in psychiatric research a practical guide /edited by Brian Dean, Joel E. Kleinman and Thomas M. Hyde1st ed.Amsterdam, Netherlands Harwood Academic Publishers19991 online resource (188 p.)Description based upon print version of record.0-203-35364-1 90-5702-298-2 Includes bibliographical references and index.Book Cover; Title; Contents; Foreword; Contributors; The Collection of Tissue at Autopsy: Practical and Ethical Issues; Psychiatric Diagnosis After Death: The Problems of Accurate Diagnosis from Case History Review and Relative Interviews; Membrane Binding Assays: Membrane Preparation and Assay Development; The Localisation and Quantification of Molecular Changes in the Human Brain Using In Situ Radioligand Binding and Autoradiography; In Situ Hybridisation Histochemistry: Application to Human Brain Tissue; Immunohistochemistry Techniques Applicable for Use with Human Brain TissueThe Processing and Use of Postmortem Human Brain Tissue for Electron MicroscopyIsolating Components of Human Brain: The Purification of A and the Alzheimer's Amyloid Precursor Protein; Analysis of Receptor Systems in Schizophrenia Using Tissue Obtained at Autopsy and Neuroimaging; IndexEssential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtained at autopsy into studies in living brain by using neuroimaging techniques. In addition, the reader is directed to suppliers of equipment and reagents that have been shown to be useful when studying human brain tissue. PsychiatryResearchNeuropsychiatryPsychiatryResearch.Neuropsychiatry.611.0188Dean Brian1828806Kleinman Joel E1828807Hyde Thomas M1828808MiAaPQMiAaPQMiAaPQBOOK9910953147103321Using CNS autopsy tissue in psychiatric research4397792UNINA