02920nam 2200565Ia 450 991087759930332120200520144314.01-282-27906-897866122790650-470-49501-40-470-49500-6(CKB)1000000000789931(EBL)456205(OCoLC)609844905(SSID)ssj0000354691(PQKBManifestationID)11259192(PQKBTitleCode)TC0000354691(PQKBWorkID)10314046(PQKB)10021992(MiAaPQ)EBC456205(PPN)14480154X(EXLCZ)99100000000078993120090223d2009 uy 0engur|n|---|||||txtccrProtein targeting with small molecules chemical biology techniques and applications /edited by Hiroyuki OsadaHoboken, N.J. John Wiley & Sonsc20091 online resource (310 p.)Description based upon print version of record.0-470-12053-3 Includes bibliographical references and index.PROTEIN TARGETING WITH SMALL MOLECULES; CONTENTS; Contributors; Preface; 1 Chemical Biology Based on Small Molecule-Protein Interaction; 2 Target Profiling of Small Molecules; 3 Novel Applications of Affinity Beads; 4 Recent Developments and Advances in Chemical Arrays; 5 Use of the Phage Display Technique to Identify the Target Protein; 6 Development of Fluorescent Probes for Small Molecules; 7 Development of Small-Molecule Ligands and Inhibitors; 8 Interaction of a Biological Response Modifier with Proteins; 9 Chemical Biology of Cell Motility Inhibitors10 Chemical Biology of Cell Surface Oligosaccharides11 Chemical Genomics Based on Yeast Genetics; 12 Data on Small Molecules and Their Target Proteins; IndexDiscover the link between the latest chemical biology approaches and novel drug therapies! Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who aProtein bindingMolecular probesProtein binding.Molecular probes.572/.633Osada H(Hiroyuki),1954-1760121MiAaPQMiAaPQMiAaPQBOOK9910877599303321Protein targeting with small molecules4200629UNINA