03285nam 2200601Ia 450 991087756730332120200520144314.01-280-36766-097866103676650-470-34930-10-471-46523-20-471-22442-1(CKB)111056485567976(EBL)152017(SSID)ssj0000330178(PQKBManifestationID)11247018(PQKBTitleCode)TC0000330178(PQKBWorkID)10318593(PQKB)10617485(MiAaPQ)EBC152017(OCoLC)53796107(EXLCZ)9911105648556797620011119d2002 uy 0engur|n|---|||||txtccrComputational methods for protein folding /edited by Richard A. FriesnerNew York Wiley20021 online resource (546 p.)Advances in chemical physics ;v. 120Description based upon print version of record.0-471-20955-4 COMPUTATIONAL METHODS FOR PROTEIN FOLDING A SPECIAL VOLUME OF ADVANCES IN CHEMICAL PHYSICS VOLUME 120; CONTRIBUTORS TO VOLUME 120; INTRODUCTION; PREFACE; CONTENTS; STATISTICAL ANALYSIS OF PROTEIN FOLDING KINETICS; INSIGHTS INTO SPECIFIC PROBLEMS IN PROTEIN FOLDING USING SIMPLE CONCEPTS; PROTEIN RECOGNITION BY SEQUENCE-TO-STRUCTURE FITNESS: BRIDGING EFFICIENCY AND CAPACITY OF THREADING MODELS; A UNIFIED APPROACH TO THE PREDICTION OF PROTEIN STRUCTURE AND FUNCTION; KNOWLEDGE-BASED PREDICTION OF PROTEIN TERTIARY STRUCTUREAB INITIO PROTEIN STRUCTURE PREDICTION USING A SIZE-DEPENDENT TERTIARY FOLDING POTENTIALDETERMINISTIC GLOBAL OPTIMIZATION AND AB INITIO APPROACHES FOR THE STRUCTURE PREDICTION OF POLYPEPTIDES, DYNAMICS OF PROTEIN FOLDING, AND PROTEIN-PROTEIN INTERACTIONS; DETECTING NATIVE PROTEIN FOLDS AMONG LARGE DECOY SITES WITH THE OPLS ALL-ATOM POTENTIAL AND THE SURFACE GENERALIZED BORN SOLVENT MODEL; AUTHOR INDEX; SUBJECT INDEXSince the first attempts to model proteins on a computer began almost thirty years ago, our understanding of protein structure and dynamics has dramatically increased. Spectroscopic measurement techniques continue to improve in resolution and sensitivity, allowing a wealth of information to be obtained with regard to the kinetics of protein folding and unfolding, and complementing the detailed structural picture of the folded state. Concurrently, algorithms, software, and computational hardware have progressed to the point where both structural and kinetic problems may be studied with a fair dAdvances in chemical physics ;v. 120.Protein foldingMathematical modelsProteinsConformationMathematical modelsProtein foldingMathematical models.ProteinsConformationMathematical models.541.305541/.08547.75Friesner Richard A1753755MiAaPQMiAaPQMiAaPQBOOK9910877567303321Computational methods for protein folding4189756UNINA